胰岛细胞瘤

胰岛细胞瘤超声诊断价值探讨

The Diagnostic Value of Ultrasonography on Islet Cell Tumor

非功能性胰岛细胞瘤的诊断及治疗（附8例分析）

The Diagnosis and Treatment of Nonfunctional Islet Cell Tumor ( a report of 8 cases )

多层螺旋CT对无功能性胰岛细胞瘤与胰腺癌的鉴别

Non-functional Islet Cell Tumor : Differentiation from Pancreatic Cancer at MSCT

胰岛细胞瘤的CT诊断（附12例分析）

CT Diagnosis of Islet Cell Tumor of the Pancreas ( Analysis of 12 Cases )

27例非功能性胰岛细胞瘤的CT诊断

CT diagnosis of non-functioning islet cell tumor

MRI结合小切口微创诊治罕见异位胰岛细胞瘤

MRI Combined with Minimal Invasive Technique to Diagnose and Treat the Rare Allotopia Insulinoma

目的研究正常胰腺及胰岛细胞瘤的多层螺旋CT灌注参数特征。

Objective To investigate the perfusion characteristics of normal pancreas and insulinoma on multi-slice spiral CT ( MSCT ) .

目的探讨功能性胰岛细胞瘤的螺旋CT诊断价值及CT扫描方案。

Objective To evaluate spiral CT features in the diagnosis of functioning islet cell tumor , to discuss CT scanning technique .

人胰岛细胞瘤cDNA文库的构建

Construction of a cDNA library of human insulinoma

胰岛细胞瘤的MRI诊断&着重探讨3DGd-DTPA动态增强MRI的应用

MRI Diagnosis of Pancreatic Islet Cell Tumors & Stressing the Applications of 3D Gd - DTPA Dynamic Enhanced MR Imaging

结论螺旋CT三期动态增强扫描在胰岛细胞瘤的诊断中有较大价值，可以为外科医生提供重要信息。

Conclusion Threephase enhanced spiral CT scanning is of great value in the diagnosis of islet cell tumor , this technique provides surgeons with important information .

9例无功能性胰岛细胞瘤TSH、FSH和LH的异位表达

Expression of tsh , fsh and LH in nonsecreting islet cell tumors

采用一种简单高效的互补脱氧核糖核酸（cDNA）克隆技术制备人胰岛细胞瘤的cDNA文库。

A cDNA library of human insulinoma was constructed by using a highly efficient and simplified cDNA cloning method .

结论：ECDUS对胰岛细胞瘤定位准确优于US、CT。

Conclusion : ECDUS is superior to spiral CT and US for the preoperative localization of insulinomas .

胰岛细胞瘤相关蛋白2胞内区与IgGFc段融合基因疫苗的构建及鉴定

Construction and identification of chimera genetic vaccine by islet cell tumor associated protein 2 and IgG Fc

目的：分析胰岛细胞瘤的MRI表现，着重探讨3DGd-DTPA动态增强MRI的应用。

Purpose : To study the MR imaging appearances of pancreatic islet cell tumors , stressing the applications of 3D Gd - DTPA dynamic enhanced MR imaging .

结论薄层动态增强的MRI序列在功能性胰岛细胞瘤的显示和定性诊断中具有重要作用。

Conclusion Thin-slice and fast dynamic MRI sequence , as exemplified by3D-VIBE sequence , is very useful in the detection and characterization of pancreatic functional islet cell tumors .

结论无功能胰岛细胞瘤症状缺乏特异性，Bus及CT应为首选的检查方法。

Conclusions Non-functional islet cell tumor lack specificity , Bus and CT are primary examination methods , immuno-histological analysis indicates various different hormones , but lacks the presence of related clinical symptoms .

目的：比较彩色多普勒超声内镜（ECDUS）与螺旋CT和腹部超声（US）术前定位诊断胰岛细胞瘤的价值。

Purpose : To compare the value of endoscopic color doppler ultrasonography ( ECDUS ), CT and US in the preoperative localization of insulinomas .

结果：胰岛素瘤3例，非功能性胰岛细胞瘤19例，超声与CT对其定位诊断正确率分别为77.8%（14/18）、75%（9/12）。

Results : The accuracy rates to locate the islet cell tumor by ultrasonography and CT were 77.8 % ( 14 / 18 ) and 75 % ( 9 / 12 ) , respectively .

结论：术前B超、CT、DSA及术中B超有助于胰岛细胞瘤准确定位，手术切除胰岛细胞瘤可获得满意效果

Conduston : B-ultrasound , CT and DSA diagnosis before operation , B-ultrasound during operation are helpful to locate functional insulinoma accurately , the surgery effect of insulinoma is satisfied

结论EUS对胰岛细胞瘤定位诊断的敏感性明显优于B超、CT、DSA等。

Conclusion EUS is superior in assessing the location of pancreatic insulinoma than other ima - ging methods such as B-US , CT , DSA .

目的：研究神经内分泌标记嗜铬粒蛋白（CG）、突触素（Syn）和神经特异性烯醇化酶（NSE）在无功能胰岛细胞瘤中的表达及意义。

Objective : To study the expression of chromogranin , synaptophysin and neuron-specific enolase in nonfunctioning islet cell tumors .

本文报告经脾动脉血管造影CT对两例功能性微小胰岛细胞瘤（直径≤1.0cm）的定位诊断。

This paper presented 2 cases of micro-functional insulinoma ( diameter ≤ 1.0cm ) localized by computed tomography splenic angiography ( CTSA ) .

结论：黄芩苷能抑制胰岛细胞瘤细胞株增殖；黄芩苷诱导所致细胞周期蛋白cyClinD1表达下调在其中起着重要作用。

Conclusion Baicalin can inhibit the proliferation of insulinoma cells , and the down-regulation of the expression of cyclin D1 might also be involved in these events .

结论：NSE、CG和SYN是功能胰岛细胞瘤的较特异的肿瘤标记物，联合检测有助于提高检测的敏感性。

Conclusion : CG , SYN and NSE may be specific tumor markers of islet cell tumors and combined detection can help to enhance the sensitivity .

方法分析经手术与病理证实的胰岛细胞瘤6例（其中多发性3例）、胰岛细胞增生症1例的MRI影像特点，并与B超对比。

Methods Analysis was made on the MRI characteristics of 6 cases with islet cell tumor ( among them 3 cases were multiple ) and 1 case with islet cell hyperplasia . All of them were confirmed surgically and pathologically .

结论人恶性胰岛细胞瘤SCID鼠原位移植模型的建立为研究人恶性胰岛细胞瘤转移机制和抗转移治疗提供了理想的动物模型。

Conclusion The two models of human malignant tumor of pancreas islet cells in SCID mice are ideal for the research of the metastatic mechanism and therapy .

实验结论：1.COMT在胰腺癌、胰岛细胞瘤及正常胰腺组织中均有表达；与正常胰腺组织相比，COMT在胰腺癌中呈高表达。

COMT expresses in the pancreatic cancer , insuloma and normal pancreatic tissue , and is over-expressed in the pancreatic cancer compared with the normal pancreatic tissue . 2 .

胰岛细胞瘤中呈铬粒素阳性NE细胞5例（71.4%），含有激素产物3例，其中1例含有单一胰多肽，另2例分别含血清素、胰岛素、胃泌素和胰高血糖素、胰多肽。

Positive NE cells were found in 5 cases ( 71.4 % ) of islet cell tumors , among which 3 cases were hormone positive ( 1 for pancreatic polypeptide , 2 for serotonin , insulin , gastrin , glucagon and pancreatic polypeptide ) .