肺小细胞癌

肺小细胞癌p53基因分析与mdm-2基因蛋白表达的关系

Relationship of the analyse of p53 gene and the expression of mdm 2 gene protein in small cell lung cancer

鉴别诊断：肺小细胞癌在诊断时，应与下述肺小细胞性肿瘤鉴别。

Differential Diagnosis : small cell lung cancer , the diagnosis should be with the following identification of small cell lung tumors .

除3例肺小细胞癌细胞角蛋白（CK）阴性外，17例肺癌均表达CK；

Tumor cells in the 17 pulmonary carcinoma cases expressed cytokeratin ( CK ) , except 3 cases of small cell carcinoma of lung .

肺小细胞癌淋巴结转移灶癌细胞核TTF-1的PU值与其原发灶癌细胞核TTF-1的PU值基本相同（P>0.05）。

In small cell lung carcinoma , TTF-1 PU of the cancerous cell nuclei of lymph node metastases was similar to that of primary carcinomas ( P > 0.05 ) .

目的：探讨c-Kit基因蛋白在肺小细胞癌（SCLC）中的表达情况及其与临床病理、预后的关系，展望酪氨酸激酶抑制剂应用于SCLC治疗之中的前景。

Objective : To investigate the effect of the expression of c-Kit protein and its relationship with clinical pathology and prognosis of SCLC . To discuss the rationale for and development of tyrosine kinase inhibitors for the treatment of human SCLC .

TTF-1在肺小细胞癌和肺腺癌中阳性表达率分别为93.3%（14/15）和93.5%（43/46），而在鳞癌中未见表达。

The positive rates of TTF-1 expression were 93.3 ( 14 / 15 ) and 93.5 ( 43 / 46 ) respectively in small cell carcinomas and adenocarcinomas of lung . In contrast , lung squamous cell carcinoma was negative .

本文对54例肺小细胞癌的组织学亚型与预后的关系进行了探讨。

The relationship of histologic subtypes and prognosis of small cell lung carcinonsa ( SCI . G ) is evaluated in 54 patients .

肺小细胞癌与类癌、不典型性类癌皆属于肺神经内分泌肿瘤，也是肺组织常见的肿瘤。

Small cell lung carcinoma and carcinoid , atypical carcinoid tumors are the property of pulmonary neuroendocrine tumors , is also a common tumor lung tissue .

结论子宫颈小细胞癌与肺小细胞癌的组织病理学和生物学行为特征相似，早期易发生盆腔淋巴结和远处转移，对化学治疗比较敏感。

Conclusion The histo - pathologic features and biologic characteristic behavior were similar between SCCC and small cell carcinoma of lung . Early metastasis and sensitivity to chemotherapy were found for both of them .

目的：通过观察肺小细胞癌细胞超微结构的变化特点，探讨肺癌细胞内的神经内分泌颗粒的分布及其意义；以肺小细胞癌为样本，鳞状细胞癌作对比。

Objective : To observe the ultrastructural characteristics in order to investigate the distribution and significance of neuroendocrine ( NE ) in the lung squamous cell cancer ( SCC ) and lung small cell cancer ( SLCC );

结果38例肺小细胞癌患者中，有9例已发生多发性骨转移，总转移率为231%。其中，男7例，占男性患者的241%，女2例，占女性患者的222%。

Results Of 38 patients , bone metastases were detected in 9 patients ( 23.1 % ) 7 of the patients were male bone metastasis , accounting for 24.1 % in male patients , 2 were female , which made up 22 2 % in female patients .

探讨了增强CT区分中央型肺非小细胞癌肿块与肺不张的可行性。

Discusses the feasibility of differentiating the central non-small-cell lung cancer from the post-obstructive lobar collapse with contrast-enhanced CT .

肺非小细胞癌患者中p53、bax的差异表达肺腺癌中K-ras基因突变及血管内皮因子的表达的临床意义及其相关性分析

Study on transcription status of p53 、 bax in lung cancers . The Meaning of K-ras Genes Mutations and the Expression of Vascular Endothelial Growth Factor ( VEGF ) in Non-small Cell Lung Cancers and Their Relations

传统的观点认为只有类癌存在神经内分泌细胞，研究发现在前列腺癌、肺非小细胞癌中存在与肺小细胞癌相似的NED。

Traditional view believed that only the carcinoid had the neuroendocrine cells , the study found that in prostate cancer , non-small-cell lung carcinoma ( N-SCLC ) had existing NED , too .

胃泌素释放肽前体在前列腺癌、肺非小细胞癌中的表达及生存关系的分析

Expression of Progastrin-releasing Peptide in Tumor of Patients with Prostate Carcinoma , Non-small Cell Lung Cancer and Prognostic Significance of Neuroendocrine Differentiation in Survival

背景与目的：肺外小细胞癌是一种少见的恶性肿瘤，有关其治疗及预后的文献报道不多。

Background and Objective : The treatment and prognosis of extrapulmonary small cell carcinoma ( EPSCC ), a uncommon malignant tumor , have seldom been reported .

肺小细胞未分化癌的多层螺旋CT表现

The Appearance of Multi-slice CT of Small Cell Undifferentiated Carcinoma

1260例肺小细胞未分化癌综合治疗结果分析

Results of combined therapy for 1 260 patients with small cell lung cancer

低分化癌占多数，肺腺癌和小细胞癌发病增高为特征，这可能与遗传因素和严重的环境污染危害有关。

The majority were poor differentiation carcinomas , and the proportion of lung adenocarcinoma and oat cell carcinoma showed a tendency to increase in all lung carcinomas . These changes may be related to genetic factors and severe environmental pollution .

II期临床研究结果显示ASA404药物对肺鳞状细胞癌或肺鳞状非小细胞癌（NSCLC）的治疗有效。

Phase II study results of the agent ASA404 showed promise in patients with either squamous or non-squamous non-small cell lung cancer ( NSCLC ) .