肉毒毒素

试验结果表明，3个浓度的D型肉毒毒素对高原鼠兔的灭杀效果与0.1%的C型肉毒毒素相当。

The control effects of D type botulin at these 3 concentrations were equal to that of 0.1 % C type botulin .

应用肉毒毒素治疗贲门失弛缓症的临床观察

Clinical studies on botulin toxin curing achalasia of cardia

大同市C型肉毒毒素草地灭鼠效果观察

Efficiency of Type-C Botulin in Killing Wild Rodent on the Grassland in Datong

A型肉毒毒素重链C片段基因的克隆及序列分析

Cloning and sequence analysis of heavy chain C fragment of Botulinum Neurotoxin Serotype A

电脉冲和布吡卡因增强A型肉毒毒素DNA核酸疫苗的免疫效果

Enhanced Effects of BoNT / A DNA Vaccines by Electric Pulses and Bupivacaine

结果C型肉毒毒素有很高的安全性，不伤害鼠类天敌；

Results The results showed that Type-C botulin had high safety without killing natural enemies of rodent .

重组肉毒毒素B重链结合区片段的表达、纯化及其抗原性分析

Expression , purification and antigenicity analysis of recombinant C-terminal fragment of botulinum neurotoxin type B heavy chain

A型肉毒毒素V形对称注射法面部除皱

Treatment of face wrinkles with V-shaped symmetrical injection of botulinum toxin

应用CT和肌电图评价A型肉毒毒素治疗良性咬肌肥大的疗效

Botulinum toxin type A for treatment of masseteric hypertrophy : An evaluation with computed tomography and electromyographic measurement

目的用浓度分别为0.10%、0.15%、0.20%的C型肉毒毒素对大同市草地害鼠进行杀灭试验，以确定草地灭鼠应用的最佳浓度。

Objective To acquire the optimum concentration of Type-C botulin used in killing wild rodent on the grassland in Datong city .

PCR合成的A型肉毒毒素重链C端结合区基因的高效表达与免疫原性分析

Immunogenicity and overexpression of PCR-synthesizing gene of heavy chain from C-terminal binding domain of botulinum neurotoxin type A

A型肉毒毒素腹腔注射对大鼠小肠通过速度及胆碱酯酶和P物质表达的影响

Effects of intraperitoneal injection of botulinum toxin A on passage velocity in small intestine and expression of acetylcholinesterase and substance P in rats

单克隆抗体在ELISA法检测B型肉毒毒素中的应用

Application of monoclonal antibody to ELISA for detecting type B toxin of Clostridium botulinum

肉毒毒素治疗贲门失弛缓症前后胃食管pH值监测分析

Gastroesophageal pH monitoring of achalasia before and after endoscopic injection of botulinum toxin : an analysis of 16 patients

肉毒毒素是肉毒梭状杆菌产生的外毒素，有7种血清型（A～G），是目前已知的毒性最强的细菌蛋白质。

Clostridium botulinum may produce any of seven known serotypes of neurotoxin ( A-G ), which are the most toxic bacterial proteins known .

抗人VEGF单链抗体基因的克隆及突变校正A型、C型肉毒毒素对鼠伤寒沙门氏菌的诱变性研究

Cloning and reverse mutation of a single chain Fv antibody against human VEGF Effect of Botulin-A or C on Salmonella typhimurium Reverse Mutation

结论：获得了B型肉毒毒素重链C端基因的表达，为肉毒毒素相关研究奠定了基础。

Conclusion : The successful cloning and expression of BoNTB / Hc are obtained , which is supposed to lay a foundation for the research of botulinum neurotoxins .

目的观察A型肉毒毒素局部注射后远隔部位F波改变，揭示对脊髓运动神经元兴奋性的影响，探讨机制。

Objective To evaluate the remote F-wave and excitability of the spinal motoneurons changes after local intramuscular administration of botulinum toxin type A.

利用0.10%、0.15%、0.20%三个浓度的C型肉毒毒素均能有效地杀灭害鼠，各浓度间灭鼠效果差异无显著性（P0.05）。

The several concentrations of Type-C botulin could kill rodent efficiently . There was no obvious difference among them in killing rodent ( P 0.05 ) .

结果：肉毒毒素ICA试纸条可以特异性检测A、B和E型肉毒毒素。

Results : Botulinum toxin types A , B , E could be detected by ICA test paper , while the enterotoxin could not .

目的：在酵母系统中实现A型肉毒毒素（BoNTa）Hc基因的可溶性分泌表达。

Objective : To express the protective fragment Hc of botulinum toxin A in Pichia pastoris .

A型肉毒毒素Hc基因的原核表达、纯化及单抗的制备

Expression , Purification and Specific Monoclonal Antibody Preparation of Protective Hc Gene of Botulinum Neurotoxin Serotype A

目的观察A型肉毒毒素（BotulinumtoxinA，BTA）对大鼠胃排空及胃肠激素分泌的影响，探讨其可能的作用机制。

Objective To study the effect of Botulinum Toxin-A on the gastric emptying and gastrointestinal hormone .

目的A型肉毒毒素重链C-端结合区（BoNT/AHc-C）的PCR拼接合成、重组表达与免疫原性分析。

Objective To express , purify and analyze the antigenicity of the heavy chain from C-terminal binding domain of botulinum neurotoxin type A ( BoNT / AHc-C ) .

A型肉毒毒素抑制大鼠变应性鼻炎鼻溢及VIP在鼻腔粘膜的免疫表达

Inhibition of rhinorrhea with botulinum toxin type A and the expression of VIP on nasal mucosa in allergic rhinitis rat

IEF纯化重组A型肉毒毒素保护性抗原

Purification of Recombinant Protective Fragment of Botulinum Neurotoxin Serotype A by IEF

目的评价A型肉毒毒素局部注射治疗颞下颌关节紊乱病（TMD）的临床疗效。

Objective To evaluate the clinical efficacy of botulinum toxin A in the treatment of temporomandibular joint disorder ( TMD ) .

目的观察不同剂量A型肉毒毒素（BTX-A）治疗痉挛型脑性瘫痪（CP）的剂量-反应关系。

Objective To study the dose-reaction of local botulinum toxin A ( BTX-A ) in the treatment of cerebral palsy .

目的：制备抗肉毒毒素A（BoNT/A）的单克隆抗体（mAb）。

AIM : To generate the monoclonal antibodies ( mAbs ) against botulinum neurotoxin type A ( BoNT / A ) .

A型肉毒毒素治疗Meige综合征及面部皮肤除皱临床研究

Botulinum Toxin Type A Therapy in Meige 's Syndrome and Facial Wrinkles