细胞的分化
- 网络cell differentiation
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研究表明:微RNA对于后生生物(多细胞动物)的细胞的分化和形体发育形成等许多方面起着重要的作用。
In metazoans , miRNA plays an important role in cell differentiation and body patterning .
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在胚分化早期RNA的迅速合成与细胞的分化及器官形成有关。
Active synthesis of RNA at the early stage of embryonic differentiation was related to cell differentiation and organogenesis .
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我们曾经报道了表达于人活化B细胞的分化抗原5C5。
In1991 , we reported a differentiation antigen5C5 expressed on human activated B lymphocyte surface .
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Toll样受体及与树突状细胞的分化和信号转导的研究进展
Study on Toll Like Receptors Differentiation of Dendritic Cell and Signal Transduction
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睾酮定向诱导MSC分化的实验研究胸腺细胞的分化
Experimental Study on the Oriented Differentiation of Mesenchymal Stem Cells with Testosterone
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PTEN的活动度在发育的早期低,从而允许细胞的分化增殖。
PTEN activity is low early during development , allowing cell proliferation .
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结论:视黄酸通过视黄酸受体介导促进体外培养的淋巴结B细胞的分化发育。
Conclusion : Retinoic acid promoted the differentiation and development of B cells , from lymph node when cultured in vitro . The effect was mediated by retinoic acid receptors .
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结果提示:胃癌细胞的分化程度愈低,其SOMmRNA表达愈强。
The results showed negative correlation between the expression of SOM mRNA and the degree of gastric carcinoma differentiation .
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正常骨髓细胞的分化与SCE值
The Differentiation of Bone Marrow Cells and Their SCE Values
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白介素6(Interleukin-6,IL-6)是参与破骨细胞的分化及功能的一种多效细胞因子。
Interleukin-6 ( IL-6 ) is a pleiotropic cytokine that is involved in osteoclast differentiation and function .
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CNTF和LIF等在神经干细胞的分化中也有重要作用。
CNTF and LIF are critical for differentiation of neural stem cells .
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NBT还原实验法分析细胞的分化指标。
NBT reduction analysis of the experimental cell differentiation indicators .
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胎肺发育晚期Survivin和Caspase-3及p53协同作用,调控着Ⅰ型和Ⅱ型肺泡细胞的分化和成熟。
Survivin cooperated with Caspase-3 , p53 in regulating differentiation and maturation of type II cells during the late development of fetal lung .
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这种作用体现在局部的旁分泌和自分泌,通过影响卵泡细胞的分化、芳香化酶的活性和cAMP水平等实现对卵泡机能的调节。
This is realized by part of paracrine and autocrine controlling follicular function through the differentiation of follicular cells , activity of aromatizing enzyme and level of cAMP .
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结论:葛根提取物能有效诱导Bel-7402人肝癌细胞的分化。
Conclusion : Root kudzuvine extract can efficiently induce differentiation of Bel-7402 human malignant hepatoma cells .
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BAY11-7082可抑制PGE2对成骨细胞的分化作用,共同作用于成骨细胞可引起细胞凋亡。
BAY 11-7082 can inhibit the osteoblast differentiation induced by PGE2 and induce the cell apoptosis with the role of PGE2 .
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毛子草化学成分及其促PC-12细胞的分化作用研究Ⅰ
Study on chemical constituents from Incarvillea arguta and their accelerating PC-12 cell differentiation
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背景与目的:转录激活蛋白AP-1与细胞的分化、增生、调亡以及肿瘤转化密切相关。
Purpose : AP-1 ( activator protein-1 ) is closely associated with cell differentiation , proliferation , apoptosis and tumorigenesis .
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本文以辣根过氧化物酶(HRP)与福氏完全佐剂混合成的乳液对雄性豚鼠作一次免疫,追踪腘淋巴结中抗体形成细胞的分化途径和变化。
The development of antibody & producing immunocytes was examined in the popliteal lymph nodes of the guinea pig during their primary response to horseradish peroxidase ( HRP ) .
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当锌浓度超过10-4mol/L,达到10-3mol/L时,可抑制成骨细胞的分化,使ALP活性下降,蛋白质合成减少。
Zinc above 10 - 4 could inhibit osteoblast differentiation and reduce ALP activity and protein synthesis .
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目的:研究神经节苷脂GM1是否介导NGF诱导的PC-12细胞的分化,及介导分化的可能机制。
Objective : To determine if ganglioside GM1 conducts the differentiation of PC-12 cells induced by NGF and if so , the way it does .
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在研究Wnt-1对人表皮干细胞的分化与增殖的影响时,我们借助了重组腺病毒基因导入技术将Wnt-1导入到人表皮干细胞内。
And then , using recombinant adenovirus gene introduction technology , we expressed Wnt-1 in epidermal stem cells .
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Thl、Th2细胞的分化方向及分泌功能已逐步被人了解,但其刺激分化的分子机制尚未完全清楚。
Th1 、 Th2cells ' differentiation and secretory function has gradually been understood but stimulating the differentiation of the molecular mechanisms are not yet fully clear .
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以往的研究表明GPI-80的表达可能与髓系细胞的分化相关。
Our previous studies suggested that GPI-80 expression might be associated with myeloid differentiation .
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胃癌组织中骨桥蛋白mRNA的相对表达量与胃癌细胞的分化程度无明显关系,但与肿瘤浸润深度、周围血管浸润、邻近淋巴结转移和远处转移显著相关(P<0.05)。
There were significant correlations between the relative expression amount of osteopontin mRNA in cancerous tissues and the degree of infiltration , vascular invasion , adjacent lymph node metastasis and distant metastasis of gastric cancer ( P < 0.05 ), but not the differentiation of cancer cells .
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凝集素受体表达差异可做为Brenner瘤细胞的分化标志,体现该瘤上皮成分分化、失分化、部分分化和多向分化的复杂状况。
The alterations of lectin receptors might serve as markers to show the complexity of differentiations , de - , part-and multi-differentiations in Brenner tumor cells .
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之前报道肌肉生长抑制素(MSTN)可以影响脂肪细胞的分化,所以我们针对MSTN对肌内DFAT细胞的影响做了进一步研究。
Previous study found that Myostatin ( MSTN ) can influence adipocyte differentiation , so we do more research about MSTN on intramuscular DFAT cells .
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虽然NOD背景的免疫缺陷小鼠已经被广泛的应用于研究人造血干细胞的分化,利用这些模型成功的研究人红细胞生成和红细胞功能还没有报道。
Although immunodeficient mice on the NOD background have been widely used to study human hematopoietic stem cell function in vivo , the successful use of these mice in the study of human erythropoiesis and RBC function has not been reported .
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水平的下调,对M-CSFR的表达是至关重要的,而M-CSFR对破骨细胞的分化和功能又是极其重要的。
Down-regulation of NFI-A levels is important for expression of the M-CSFR , which is critical for osteoclast differentiation and function .
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结果提示Gg(GM3)的生物合成和ST1的活性变化与HL-60细胞的分化增殖有关。
The findings suggest that the changes in biosynthesis of ganglioside ( GM 3 ) and activity of ST 1 may be associated , at least , with HL-60 leukemia cell differentiation and proliferation .