组织相容性抗原

zǔ zhī xiānɡ rónɡ xìnɡ kànɡ yuán
  • histocompatibility antigen;antigen histocompatibility
组织相容性抗原组织相容性抗原
  1. 组织相容性抗原HLA-B27检测对强直性脊柱炎患者疾病活动期的评估价值

    Significance of histocompatibility antigen HLA-B27 in evaluating the patients with ankylosing spondylitis at the active phase

  2. 结论次要组织相容性抗原HA-1可作为造血干细胞移植后抗白血病治疗的靶点。

    It is concluded that the minor histocompatibility antigen HA-1 can be considered as a target of immunotherapy against leukemia after HSCT .

  3. 人类组织相容性抗原-gmRNA表达与不明原因习惯性流产关系的初步研究

    Preliminary Study on the Relationship between Human Histocompatibility Leukocyte Antigen G mRNA and Recurrent Spontaneous Abortion

  4. HLA(人类白细胞抗原)是人类主要组织相容性抗原系统。

    The HLA ( Human Leukocyte Antigen ) is the major antigenic system of histocompatibility in human .

  5. 腹腔注射脂多糖(LPS)制备小鼠脓毒症模型,用流式细胞仪检测DC表面分子CD11c、CD86和主要组织相容性抗原复合物(MHC)的表达;

    The sepsis model of mice was reproduced by the injection of lipopolysaccharides ( LPS ) .

  6. 采用免疫组化技术,分析了40例乳腺癌石蜡标本主要组织相容性抗原HLA-DR与各项临床病理参数和生存预后的关系。

    We studied 40 cases of breast cancer to examine the correlation of HLA DR antigen expression on tumor tissues with clinicopathological features .

  7. 带有蓖麻毒蛋白的供体脾细胞,一方面可提供特异移植抗原(主要组织相容性抗原)使特异的T,B淋巴细胞识别;

    Because Toxic Cell 's have intact transplantation antigen ( Major Histocompatible Antigen Complex , MHC ) on their surface , they can be specifically recognized and lysed by receptor 's T , B lymphocytes .

  8. 目的探讨宫颈癌与人类组织相容性抗原(HLA)表达缺失和人乳头瘤病毒(HPV)16、18感染的关系。

    Objective : To investigate the relationship between the expression down-regulation of HLA-I antigen , the infection of HPV16,18 and the cervical cancer .

  9. 目的:探讨孕酮对人早孕滋养层人类白细胞主要组织相容性抗原(HLA)-G基因转录的调控作用。

    Objective : To investigate the regulating effect of progesterone on transcription of human leukocyte antigen-G ( HLA-G ) in human trophoblast during early pregnancy .

  10. 很有趣的是,被作用的靶分子就是HLA-G所属的主要组织相容性抗原家族的一员。

    Interestingly , the targets are members of the major histocompatibility complex family to which HLA-G belongs .

  11. 随着其抗原结合分子及T细胞信使生物学功能本质的揭示,MHC为什么是主要组织相容性抗原的谜底就昭然于世。

    When their essential biological function as antigen-binding molecules and informers for T cells was unveiled , an explanation of why MHC also acts as major histocompatibility antigens was provided .

  12. 近年的临床研究表明,GVHD与次要组织相容性抗原(mHAgs)有重要关系。

    GVHD is greatly related with minor histocompatibility antigens ( mHAgs ) in recent clinical studies .

  13. 组织相容性抗原CD45RO肿瘤坏死因子在桥本氏甲状腺炎和亚急性甲状腺炎的表达与免疫损伤的关系及临床意义

    The Relationship Between The Expression of HLA-DR , CD45RO , TNF - α and Immune Injury in HT and SAT and Its Clinical Significance

  14. 结论抗TCRαβ单克隆抗体联合大剂量供体骨髓细胞输注可以在组织相容性抗原完全不相同的成年小鼠间成功地诱导出皮肤移植物的长期耐受。

    Conclusion Treatment of anti-TCR αβ monoclonal antibody combined with high dose of donor bone marrow cells infusion can successfully induce a long-term tolerance in BALB / c mice to B6 skin graft .

  15. B组枯否氏细胞膜表面主要组织相容性抗原复合物(MHC)、CD80、CD86分子明显低于A组(P<0.05),C组高表达上述膜表面分子。

    The amount of MHC , CD80 , CD86 on KCs membrane in group B was significantly lower than that in group A ( P < 0 . 05 ), but these membranous proteins were highly expressed in group C.

  16. 方法采用细胞培养技术和流式细胞仪技术研究液氮低温保存对大鼠主动脉平滑肌细胞和成纤维细胞主要组织相容性抗原类(MHC类抗原)表达的影响。

    METHODS By means of cell culture and flow cytometry we studied the effect of fluid nitrogen cryopreservation on the expression of MHC ⅰ antigen of smooth muscle cells and fibroblasts of aortic homografts of rats .

  17. 然而由于其表达组织相容性抗原-II(MHC-II),这些分子可刺激同种异体抗宿主反应,所以限制了MSC在修复医学中的应用。

    The expression of MHC class II on MSC , however , could deter their use in repair medicine , since these molecules could stimulate an allogeneic host response .

  18. 方法应用流式细胞计数仪辅以荧光标记组织相容性抗原Ⅱ类分子四聚体染色,从自发性糖尿病的NOD小鼠和非糖尿病的BALB/c小鼠中分离出谷氨酸脱羧酶(GAD)多肽特异性T细胞。

    Methods Glutamic acid decarboxylase ( GAD ) - peptide specific T cells with fluorescein-labelled Class ⅱ MHC tetramers were isolated by flow cytometer from NOD mice with spontaneous diabetes and diabetes resistant BALB / c mice .

  19. 本研究以次要组织相容性抗原HA-1为靶点,构建HA-1树突状细胞核酸疫苗用于造血干细胞移植后抗白血病治疗。

    The purpose of this study was to construct a HA-1-DC nucleic acid vaccine and to induce anti-leukemia effect after hematopoietic stem cell transplantation ( HSCT ) .

  20. 方法供者(NIH小鼠)主要组织相容性抗原(H-2Ag)与天花粉毒素(TCS)经异型双功能试剂SPDP、2-IT交联,制备免疫毒素(Ag-TCS);

    Methods Donor ( NIH mouse ) H-2 antigen and trichosanthin ( TCS ) was conjugated to immunotoxin ( Ag-TCS ) by heterobifunctional reagent SPDP ? 2-IT .

  21. 猪白细胞抗原(SwineLeucocyteAntigen,SLA)复合体是由存在于7号染色体上一群紧密连锁并具有高度多态的基因所组成的一个染色体区域,编码主要组织相容性抗原。

    The Swine Leucocyte Antigen ( SLA ) complex is a chromosomal region consisting of series of closely linked loci and locating on chromosome 7 , which have highly polymorphism and encode the major histocompatibility antigen , and play a central role in the immune system .

  22. 【目的】研究病毒性心肌炎(VMC)心肌组织相容性抗原Ⅱ类(MHCⅡ类抗原)的表达特点,探索轻度、不典型VMC的法医病理学诊断方法。

    To investigate the expression of histocompatibility antigens class ⅱ ( MHC ⅱ antigen ) on myocardium in acute viral myocarditis ( VMC ) and study the diagnostic method for mild atypical VMC in the field of forensic pathology .

  23. 了解宿主对龋病的易感情况是口腔龋病预防的一个重要方向,而与龋病易感性相关的宿主因素很多,但用主要组织相容性抗原MHC作为相关因素还是一较新的研究方向。

    One of the chief aspects of preventive dentistry is to get some idea about personal susceptibility to caries . There are many host factors related to this susceptibility , however , taking MHC ( major histocompatibility complex ) as one host factors is a comparative new field .

  24. 环孢霉素A对培养的人角朊细胞主要组织相容性抗原表达的影响

    Effect of cyclosporin A on MHC expression of cultured human keratinocyte

  25. 小鼠组织相容性抗原的提取与纯化

    Extraction and Purification of Major Histocompatibility Complex Antigen in Mouse

  26. 组织相容性抗原HLA&DP在6~11周的胚肝中也表现为阳性。

    The histocompatibility antigen HLA DP is also positive during 6 11 wks.

  27. 胃癌细胞组织相容性抗原组织的丧失及其意义

    Histocompatibility Antigen Loss in Gastric Carcinoma Cells and its Significance

  28. 原发性干燥综合征与人类组织相容性抗原-DRβ基因

    Study on the relationship between primary Sjogren syndrome and HLA DR β gene

  29. 各组大鼠肝脏中人主要组织相容性抗原-Ⅰ类阳性率。

    Positive rate of main histocompatibility antigen in liver ;

  30. 大鼠抗小鼠组织相容性抗原抗体的制备与纯化

    Preparation of rat antibodies against mouse major histocompatibility antigen