神经干细胞

体外分离与培养SD乳鼠神经干细胞实验过程中部分方法的改进

Improvement of some methods in isolating and culturing neural stem cell from SD neonatal rats in vitro

Numb基因在培养神经干细胞中的表达

Expression of numb gene in cultured neural stem cell

B组注入神经干细胞的细胞液，C组注入在体外定向诱导为胆碱能神经元的细胞液；

Group C was injected cell sap of cholinergic neurons .

RA和cAMP诱导神经干细胞离子通道的表达

Expressed on neural stem cells induced by RA and cAMP

IL-6促进骨髓源性神经干细胞增殖的实验研究

Interleukin-6 promotes proliferation of bone marrow-derived neural stem cells : an experimental study

神经干细胞移植对AD鼠基底前脑NOS阳性神经元的影响

Effects of NOS-positive Neurons of Basal Forebrain of AD Rat after Neural Stem Cells Transplantation

神经干细胞增殖分化过程中Notch通路信号分子的表达

Expression of Notch signal molecules during proliferation and differentiation of neural stem cells

结论NGF有诱导神经干细胞定向迁移的作用。

Conclusion NGF could induce directional migration of neural stem cells .

超顺磁氧化铁标记神经干细胞移植治疗帕金森病大鼠脑MRI改变的研究

Study the changes of brain MRI following transplantation of SPIO labeled neural stem cells in treatment of Parkinson 's disease in rat

Notch信号与神经干细胞分化

Notch signal and neural stem cell differentiation

同时，我们发现在神经干细胞中Notch对其自我增殖具有充分但不必要的作用。

We also identify that Notch is sufficient but not necessary for the neuroblast self-renew .

bFGF诱导移植神经干细胞在损伤脊髓内分化的研究

BFGF Regulates the Differentiation of Neural Stem Cells Transplanted Into Injured Spinal Cord in Rats

大鼠胚脑皮质和中脑神经干细胞移植治疗PD模型鼠的比较研究

The comparison of cell transplantation in PD model rats between cortical and mesencephalic neural stem cells prepared from fetal rats

神经干细胞原代培养及GABA能神经元的诱导分化

Primary culture of neural stem cells and induction and differentiation of GABA neurons

外源性绿色荧光蛋白和蛋白酪氨酸激酶受体B基因在大鼠骨髓源性神经干细胞内稳定表达的检测特征

Detection characteristics of the stable expression of recombinant plasmid enhanced green fluorescent protein-C 2-protein tyrosine kinase B gene in the neural stem cells derived from the bone marrow stromal cells of rats

目的探讨TH基因修饰的神经干细胞脑内移植对帕金森病（PD）的治疗作用。

Objective To study therapeutic effect of intracerebral transplantation of TH - gene modified neural stem cells ( NSCs ) on PD rats .

结果：①原代培养获得了Nestin染色阳性的神经干细胞。

RESULTS ① Nestin positive neural stem cells were obtained through primary culture .

神经干细胞有丝分裂过程中nestin表达变化

Variation of nestin expression during neural stem cells mitosis

CNTF和LIF等在神经干细胞的分化中也有重要作用。

CNTF and LIF are critical for differentiation of neural stem cells .

目的寻找对神经干细胞（NeuralStemCells，NSCs）的增殖、分化和存活有促进作用的单味中药成分，进而确定对NSCs的增殖和分化有影响的中药有效成分。

Objective To find a simple traditional Chinese medicine that certainly activates the proliferation , differentiation and survival of neural stem cells ( NSCs ) .

大鼠脊髓损伤BDNF基因修饰神经干细胞移植后HRP逆行示踪

Retrograde HRP tracing after transplantation of BDNF genetically modified NSCs at spinal cord injury in rat

[方法]从胎龄14～16天的Wistar大鼠脑组织分离、培养获得神经干细胞；

Methods Neural stem cells was dissociated and cultured from 14 ~ 16 days old embryonic Wistar rat brain tissue .

结果：在原代及传代细胞中有Nestin阳性细胞即神经干细胞。

Results : Nestin positive cells were found in the culture and daughter clones .

GDNF与IL-1β体外诱导小鼠中脑神经干细胞分化作用的实验研究

Experimental study on differentiation of mouse mesencephalic neural stem cells induced by GDNF and il-1 β in vitro

当前在人脑胶质瘤干细胞的体外培养中均采用加入LIF等的无血清神经干细胞培养液。

The CSCs of human glioblastoma in vitro were cultured in serum-free neural stem cell medium with LIF .

NT-3基因修饰施万细胞促进神经干细胞体外分化为神经元样细胞

NT-3 genetically modified Schwann cells promote neural stem cells to differentiate into neuron-like cells

GM1和NGF对神经干细胞体外增殖的影响

Effects of ganglioside 1 and nerve growth factor on the proliferation of neural stem cells in vitro

离体培养神经干细胞中NMDA受体亚单位NR2B的表达

The expression of NMDA receptor subunit 2B in neural stem cells in vitro

结论：SD乳鼠体外培养神经干细胞取材最佳位置应该是脑室管膜或室管膜下。

CONCLUSION : Neural stem cells from ependyma or under ependyma in lateral ventricle of SD neonatal rats are much better than those from other areas of brain .

目的将骨髓来源和脑来源神经干细胞（NSCs）移植入大鼠脑损伤模型，比较两种细胞移植治疗脑外伤的效果和临床应用价值。

Objective To compare the clinical effectiveness of treatment injured brain by transplanting NSCs induced from rat bone marrow and brain .