磷酰胺

叠氮亚磷酸酯及叠氮磷酰胺的合成

Synthesis of Phosphite Ester and Phosphoramide Containing Azido Groups

肿瘤的化学治疗Ⅸ.磷酰胺及磷酸酯类氮芥的合成

Tumour chemotherapy ⅸ . nitrogen mustards of phosphoramide , phosphoramide ester and thioester

HPLC法测定复方环磷酰胺胶囊中环磷酰胺的含量

Assaying of cyclophosphamide in compound cyclophosphamide capsules by HPLC

联萘酚磷酰胺2DNMR及构象分析

2D NMR and conformational analysis of 2 , 2 ' - dihydroxy-1,1 ' - binaphthyl phosphoramidate

（S，R）联萘酚磷酰胺包合物的合成及晶体结构

The Synthesis and Crystal Structure of Clathrate Compounds of ( S , - R ) - 2 , 2 ' - Dihydroxy-1,1 ' - Binaphthyl Phosphoramidate

用固相亚磷酰胺法（solid-phasephosphoramiditemethod）合成了人α-心钠素（简称α-hANP）的全基因。

A total gene for a-human atrial natriuretic peptide ( a-hANP ) has been chemically synthesized by solid-phase phosphoramidite method .

然后，按照固相亚磷酰胺化学法的要求，将修饰后的脱氧鸟苷进行N2位的碱基保护，以及脱氧核糖上的羟基保护，合成得到DNA单体。

Then we modified the deoxyguanosine derivative according to solid-phase phosphoramidite method , which should protect N2 position on the base , as well as protect the hydroxyl groups on the deoxyribose with certain bases , and got the DNA monomer .

方法以固相亚磷酰胺法合成吖啶、6碳氨基连接臂修饰的TFO，并以温和法切割和脱保护；

Method TFO modified by acridine and amino modifier C6 were synthesized by solid phase phosphoramidite chemistry , then deprotected mildly .

采用适合批量生产的亚磷酰胺方法合成反义寡核苷酸（5′cgatggcacggcgcactt3′）。

ODN ( 5 ' cga tgg cac ggc gca ctt 3 ' ) targeted to survivin mRNA was synthesized , we introduced a simple phosphoramidite method to produce ODN .

将包裹于脂质体内硫代磷酰胺ODNs（S-ODNs）静脉注射，90分钟内，超过30%的S-ODNs被Kupffer细胞滤过，这低于体重的0.2%。

When phosphorothioate ODNs ( S - ODNs ), encapsulated in liposomes are injected intravenously , within 90 min , > 30 % of the injected S-ODNs are sequestered by Kupffer cells , which account for less than 0 . 2 % of the body weight .

膨胀型阻燃剂新戊二醇乙撑磷酰胺的合成微胶囊红磷膨胀型阻燃剂的制备及应用

Preparation and Application of Intumescent Flame Retardant of Microencapsulated Red Phosphorus

目的初步阐明葡磷酰胺在大鼠体内的代谢情况。

Aim To elucidate the metabolic pathway of glufosfamide in rats .

O-乙基-N-烷基（取代硫脲基）硫代磷酰胺酯的合成及其生物活性

Synthesis and Biological Activity of O-Ethyl-N-Alkylphosphoro ( thioureido ) thioates

取代基对硫代磷酰胺酯摩擦磨损的影响

Influence of substituents on friction and wear of thiophosphoric amidates

含磷聚酰亚胺的合成与抗原子氧性能生物素酰亚磷酰胺，生物素化亚磷酰胺

Synthesis and atomic oxygen resistance of phosphorus-containing polyimide biotinylated phosphoramidite

一种新型含溴磷酰胺酯阻燃剂的合成

Synthesis of a Novel Bromine Phosphamide Ester Flame Retardant

用昆虫谷氨酸电位检测磷酰胺酯化合物的活性

Glutamate potential of insect examine activity of bpons compounds

目的建立复方环磷酰胺胶囊中环磷酰胺的含量测定方法。

Objective To establish a method for assaying of cyclophosphamide in compound cyclophosphamide capsules .

亚磷酰胺&过渡金属催化的交叉偶联反应的研究

Phosphoramidite-Transition Metal Catalyzed Cross - Coupling Reactions

骨髓间充质干细胞对磷酰胺氮芥诱导卵巢颗粒细胞凋亡的保护作用

Protective effect of bone marrow mesenchymal stem cells on chemotherapy-induced apoptosis of ovarian granulosa cells

环1磷酰胺通过明显抑制骨形成而导致骨量减少，骨显微结构退化等典型骨质疏松特征的出现。

Cyclophosphamide causes osteopenia and microstructure degradation in rats , which are the typical feature of osteoporosis , by significantly inhibiting bone formation .

其中四组中环磷酰胺、全反式维甲酸对新西兰兔较甲氨蝶呤及丙戊酸钠具有更好的脊髓损伤作用。

Among four groups cyclophosphamide , all-trans retinoic acid on rabbits and valproate compared with methotrexate has better spinal cord injury . 3 .

提高O，O-二甲基硫代磷酰胺的质量，可明显提高单位潜在废物的产率。

When the quality of O , O-dialkyl phosphoroamidothioate is rised , the ratio of product mass to undesirable material mass can be increased obviously .

本文包括两章：第一章新型手性（？）唑啉-亚磷酰胺配体的合成及其在取代、氢化反应中的应用；第二章旋光纯富马酸伊布利特合成研究。

The dissertation consists of two parts : Part 1 . Synthesis and application of chiral oxazoline-phosphoramidite ligands in the substitution and hydrogenation . Part 2 .

双复磷和酰胺磷定对梭曼中毒神经肌肉接头终板区持续性去极化的对抗作用

Antagonism of obidoxime and HI-6 against sustained depolarization in endplate area of neuromuscular junction intoxicated with soman