皮肤乳头状瘤

芳维A酸乙酯对小鼠皮肤乳头状瘤形成过程中ODC、PCNA的影响

Influence of arotinoid ethylester on ODC and PCNA in the course of producing mouse skin papilloma formation

长期多次涂抹PMA，可以诱发小鼠皮肤乳头状瘤的发生进而实现化学致癌的发生发展。

Long-term repeated PMA smearing , could induce the occurrence of skin papilloma in mice so as to realize the occurrence and development of chemical carcinogenesis .

20（R）-人参皂苷Rh2对DMBA/巴豆油诱发小鼠皮肤乳头状瘤的抑制作用研究

Inhibition Effect of 20 ( R ) - ginsenoside Rh_2 Skin Tumor_bearing Mice Induced by DMBA / Croton Oil

目的：研究5-氨基酮戊酸光动力学疗法（ALA-PDT）对小鼠皮肤乳头状瘤的治疗作用。

Objective : To study the inhibition effect on induced skin papillomas in mice with photodynamic therapy ( PDT ) using 5-aminolevulinic acid ( 5-ALA ) .

目的通过测定小鼠二阶段皮肤乳头状瘤模型中鸟氨酸脱羧酶（ODC）、增殖细胞核抗原（PCNA）的变化，探讨芳维A酸乙酯的癌化学预防作用机制。

Objective To study the mechanism of arotinoid ethylester on cancer chemoprevention by assaying ornithine decarboxylase ( ODC ) activity and proliferative cell nuclear antigen ( PCNA ) index of mouse skin in the process of mouse papilloma formation .

5-氨基酮戊酸光动力治疗小鼠皮肤乳头状瘤的实验研究

Photodynamic Therapy for Induced Skin Papillomas in Mice Using 5-aminolevulinic Acid

结果表明，芳维A酸乙酯对DMBA/巴豆油诱发的小鼠皮肤乳头状瘤有明显的消退作用，其作用与诱导异常增殖表皮细胞凋亡有关。

The result showed that arotinoid ethylester had marked regressive effect on DMBA / corton oil induced papillomas of skin of mice . The effect was related with the induction of apopotosis of abnormally proliferative epidermal cells .