痛痛病

大部分科学家援引20世纪60年代日本出现的痛痛病（itai-itaidisease），相信这是可确认的最早病例。

Most scientists cite the identification of itai-itai ( ouch-ouch ) disease in Japan during the 1960s as the first recognition of this problem .

ACAP主要考虑制定污染防治政策，监测、评估和补偿环境污染（如水俣病、痛痛病、呼吸道疾病等）造成的损害。

Unlike ACAP concerned mainly with anti-pollution policy formulation , monitoring and evaluation as well as compensation to the environmentally disadvantaged resulting from specific environmental pollution such as Minamata methyl-mercury pollution , Itai-Itai limb and joint paralysis , Yokkaichi respiratory disease , and Niigata Minamata .

痛痛病、四日市哮喘病、水俣病和新泻水俣病，即所谓的四大公害病，可以说就是工业化进程中带来的负面影响。

The so-called four diseases caused by environmental pollution , are the negative influence brought by the industrialization .