在本文中,根据活性拼合原理和生物电子等排取代原理,设计合成了甲氧丙烯酸酯的生物电子等排体二甲氨基丙烯酸甲酯的1,2,4-恶&(?)
In this thesis , fourteen novel compounds which contain 1,2,4-oxadiazoles are designed and synthesized on the base of hybridization principle and bioisosterism .