灵芝多糖

灵芝多糖的药理和保健作用及应用前景

Pharmacological and Health Effect of Ganoderma lucidum Polysaccharide and its Application Prospect

富含淀粉固体菌质中灵芝多糖含量的测定造纸原料多戊糖含量的测定

Determination of Ganoderma Lucidum polysaccharide from solid fungal substance rich in starch

灵芝多糖液体发酵条件的优化和pH控制策略的研究

Optimization of submerged fermentation conditions for Ganoderma polysaccharide

结果表明：日本菌种7号培养的灵芝多糖含量最高，野生菌种E号培养的灵芝多糖含量最低。主题词：灵芝／化学；

The results showed that the content of Ganoderma polysaccharides in Japan GL strain No.

灵芝多糖对小鼠T细胞胞浆游离Ca~（2+）浓度和胞内pH的影响

Effect of Ganoderma polysacchride on intracellular free calcium and intracellular pH in murine T cells

灵芝多糖对老年小鼠脾细胞DNA多聚酶α活性及免疫功能的影响

Effects of Ganoderma Polysaccharides on the activity of DNA polymerase α of splenocytes and immune function in aged mice

灵芝多糖引起的小鼠脾细胞核DNA，RNA含量及核质比的变化

Changes of nuclear DNA , KNA contents and ratio of nucleus to cytoplasm of murine splenocytes induced by Ganoderma lucidum polysaccharides

灵芝多糖和灵芝三萜是灵芝（Ganoderma）的主要生物活性成分。

Polysaccharides and triterpenes are main bioactive compounds of Ganoderma sp. .

灵芝多糖体外对小鼠脾细胞IL-2，IL-3mRNA表达的影响

Effects of Ganoderma polysaccharide on IL-2 and IL-3 mRNA expressions in murine splenocytes in vitro

灵芝多糖拮抗前列腺素E2对小鼠脾细胞IFN-γ和TNF-αmRNA表达的抑制作用

Ganoderma polysaccharides antagonize prostaglandin E2-induced suppression of murine splenocyte IFN - γ and TNF - α mRNA expression

灵芝多糖增强人脐血LAK细胞活性电镜观察研究

An electron microscopic study on potentiation of GLP for cb ─ lak cells activity

灵芝多糖对人脐血LAK细胞活性的影响

Effect of Polysaccharide of G. Lucidum on Lak Cell Activity of Human Cord Blood

结论灵芝多糖可明显抑制佐剂性关节炎大鼠血清IL-12的分泌。

Conclusion Ganoderan can inhibit the excretion of IL-12 in adjuvant arthritis rats ' serum .

结果灵芝多糖可减少H2O2诱导角质形成细胞丙二醛的沉积，增加抗氧化酶的活性。

Results Ganoderma polysaccharides reduced the accumulation of MDA induced by H_2O_2 and enhanced the activity of antioxidases .

灵芝多糖对IEC-6细胞促增殖、迁移与分化作用

Ganoderma Lucidum Polysaccharides Accelerated IEC-6 Cells Proliferation , Migration and Differentiation

结果与对照组相比，灵芝多糖组对佐剂性关节炎大鼠血清IL-12的分泌具有明显的抑制作用（P<0.01）。

Results Compared with control group , ganoderan can inhibit the excretion of IL-12 in adjuvant arthritis rats ' serum ( P < 0.01 ) .

四种中草药多糖中灵芝多糖对黄颡鱼肌肉中氨基酸总量及必需氨基酸含量的提升作用最佳，但效果不显著（P0.05）。

GLP in the four polysaccharides , which had the best promotional effects on the contents of amino acids and essential amino acids , however there was not significant effects ( P0.05 ) . 2 .

目的：探讨灵芝多糖GLB的抗肿瘤作用及其机制。

To study the antitumor activity and mechanism of Ganoderma polysaccharides ( GL B ) .

结果灵芝多糖锗对小鼠溶血素形成和溶血空斑形成有显著的升高作用，对ConA、LPS诱导体外小鼠T、B淋巴细胞增殖有明显的兴奋作用。

Results Saccharum germanium of glossy ganoderma had effects on the increase of mices hemolysin and hemolysis aero - macule formation , and has stimulating effects on mices T. B lymphocytes multiplication induced by ConA , LPS .

DG组和DSG组每日灌胃灵芝多糖测200mg/kg，对照组灌服同体积的蒸馏水，共持续7周。

DG group and group having daily lavage ganoderma lucidum polysaccharides measurement 200mg / kg , served with the volume control irrigation distilled water , lasting seven weeks .

目的观察灵芝多糖拮抗前列腺素E2（PGE2）对小鼠脾细胞干扰素γ（IFN-γ）和肿瘤坏死因子α（TNF-α）mRNA表达的抑制作用。

Objective To determine if Ganoderma polysaccharides can antagonize prostaglandin E2 ( PGE2 ) - induced suppression of murine splenocyte interferon γ ( IFN - γ) and tumor necrosis factor α ( TNF - α) mRNA expression .

本研究以成年昆明小鼠为实验对象，观察了灵芝多糖对顺铂所致高岭土摄取行为（一种公认的恶心、呕吐动物模型）及脑内Fos蛋白表达的影响。

This research is to explore the influence of ganoderma lucidum polysaccharides on both kaolin intake of KM mice ( a recognitive nausea / vomiting model ) and Fos expression in their brain induced by cisplatin . Results : 1 .

研究灵芝多糖（GLB7）对小鼠细胞免疫功能调节作用的影响。

To study the effects of Ganoderma lucidum polysaccharide ( GLB7 ) on cellular immune function in mice .

顺铂+灵芝多糖组血清Scr、BUN降低，肾皮质组织MDA含量降低，SOD活性、GSH-Px活性升高，与顺铂组比较有显著差异（P<005）；

The content of Scr and BUN in GLP + CDDP group was significantly lower than that of CDDP group ( P < 0.05 ) . The concent of MDA declined and the activity of SOD and GSH_Px increased in renocortical tissue ( P < 0.05 ) .

目的探讨灵芝多糖对佐剂性关节炎大鼠血清IL-12的影响.方法用弗氏完全佐剂诱导大鼠佐剂性关节炎模型，以IL-12EIA检测试剂盒检测大鼠血清IL-12水平。

Objective To study the effects of ganoderan on adjuvant arthritis rats ' serum IL-12.Methods Induce the model of arthritis in rats by freund 's complete adjuvant ( FCA ) and then detect the level of IL-12 in rats'serum by IL-12 EIA kit .

结果：灵芝多糖可明显提高小鼠骨骼肌SOD及心肌GSH-Px活性，明显降低力竭小鼠骨骼肌MDA水平及血清GPT及CK水平，减轻肝脏及骨骼肌损伤。

Results : Glossy ganoderma Polysaccharide could obviously raise SOD activity of muscle and GSH-Px activity of myocardium in mice at rest , as well as decrease MDA of muscle 、 GPT and CK of serum in exhausted mice obviously and reduce the injury of liver and muscle .

目的：研究灵芝多糖（Gl-PS）在抗原提呈阶段对体外培养树突状细胞（DC）诱导特异性细胞毒性T-淋巴细胞（CTL）功能的调节及其机制。

AIM : To study the regulatory effects of Ganoderma lucidum polysaccharides ( Gl-PS ) on cytotoxicity and mechanism of specific cytotoxic T-lymphocytes ( CTL ) induced by dendritic cells ( DC ) in vitro during the stage of antigen presentation .

目的：研究黑灵芝多糖（PSG-1）对小鼠脾淋巴细胞增殖及诱生细胞因子的影响。

Objective : To investigate the effect of polysaccharides from Ganoderma atrum ( PSG-1 ) on murine spleen lymphocyte proliferation and induction of cytokine .

目的研究灵芝多糖（GLB7）对小鼠T细胞三磷酸肌醇（IP3）和二酰基甘油（DAG）的作用，确定其对T细胞信号转导途径。

OBJECTIVE To investigate the effects of GLB 7 on inositol trisphosphate ( IP 3 ) and diacylglycerol ( DAG ) in murine T cell and to provide a scientific evidence for its immunomodulatory mechanism .

与联合注射格拉司琼和顺铂组相比，联合注射灵芝多糖和顺铂组的高岭土摄取量在连续4d之内均较小，在第1d其差异有显著性，在第2-4d差异无统计学意义。

Compared to granisetron and cisplatin group , the intake of kaolin in ganoderma lucidum polysaccharides and cisplatin group was less in the 4 days , difference had significance ( P0.05 ) on 1st day , no significant difference on 2nd - 4th day . 6 .