泡沫细胞

Toll样受体4在泡沫细胞形成中的作用及中医药干预研究

Effect of Toll Like Receptor 4 in Foam Cell Formation and Intervention Study with Chinese Medicine

LPS和IL-10对低密度脂蛋白诱导泡沫细胞形成的影响

The effect of LPS and IL-10 on formation of foam cell induced by LDL

肝X受体α在泡沫细胞胆固醇流出中的调控作用

The Action of Liver X Receptor α on Cholesterol Efflux in THP-1 Macrophage-Derived Foam Cells

溶血卵磷脂对载脂蛋白E基因缺陷小鼠腹腔巨噬细胞源泡沫细胞胆固醇外流的影响

Effects of Lysophosphatidylcholine on Cholesterol Efflux from Apolipoprotein E Gene Deficient Mouse Peritoneal Macrophage-Drived Foam Cells

PPARγ基因转录与单核巨噬细胞来源的泡沫细胞形成

PPAR γ gene expression and macrophage-derived foam cell formation

Ghrelin对巨噬细胞源性泡沫细胞形成的抑制作用及其机制研究

Effects and Mechanisms of Ghrelin Inhibit Macrophage-derived Foam Cell Formation

肥大细胞抑制HDL3介导THP-1巨噬细胞源性泡沫细胞胆固醇流出的研究

Studies of Mast Cells Inhibiting HDL_3-induced Cholesterol Efflux from THP-1 macrophage-derived Foam Cells

以载脂蛋白E基因缺陷小鼠腹腔巨噬细胞源泡沫细胞为研究对象，观察溶血卵磷脂对泡沫细胞胆固醇外流的影响以及初步探讨其机制。

Aim To explore the effects of lysophosphatidylcholine ( LPC ) on cholesterol efflux from apolipoprotein E ( apo E ) gene deficient mouse peritoneal macrophage foam cells .

血管紧张素Ⅱ对THP-1源性泡沫细胞ATP结合盒转运子A1表达的调控作用

Regulation of angiotensin ⅱ on expression of ATP-binding cassette transporter A1 in THP-1 derived foam cells

肿瘤坏死因子-α对泡沫细胞胆固醇流出及ATP结合盒转运子A1表达的影响

Effect of tumor necrosis factor-it on the expression of ATP binding cassette transporter A1 in THP-1 macrophage foam ceils

动脉粥样硬化敏感小鼠C（57）BL／6J腹膜巨噬细胞源性泡沫细胞模型的建立

Founding of a Model of Macrophage-derived Foam Cell from Peritoneum in C_57BL / 6J Mouse which Is Susceptible to Atherosclerosis

THP-1巨噬细胞源性泡沫细胞模型的建立及鉴定

Establishment and Identification for Macrophage-derived Foam Cell Model of THP-1 Cell Line

小檗碱对THP-1巨噬细胞源性泡沫细胞胆固醇流出的影响

Effects of berberine on cholesterol efflux in THP-1 macrophage derived foam cells

肺炎衣原体诱导THP-1源性泡沫细胞形成的机制

Mechanisms of THP-1-derived Foam Cell Formation Induced by Chlamydia Pneumoniae

动脉粥样硬化斑块内泡沫细胞c-sis和c-myc基因表达的研究

Expression of cellular oncogenes of foam cells in atherosclerotic plaques

单核细胞在内膜聚集后衍生为巨噬细胞，巨噬细胞吞噬氧化型LDL变成泡沫细胞。

After endometrium mononuclear cells in gathered to macrophage derived and macrophage cell oxidation type LDL into foam cells .

结论：OPN参与冠状动脉钙化的调节，其主要来源于巨噬细胞和巨噬细胞源性的泡沫细胞。

Conclusion : OPN plays a role in the calcification of atherosclerotic plaques of coronary artery ;

高压力及曲格列酮对THP-1源泡沫细胞ATP结合盒转运子A1表达的影响

Effect of high hydrostatic pressure and Troglitazone on ATP binding cassette transporter A1 expression in TPH-1 macrophages-derived foam cells

CpG对动脉粥样硬化早期巨噬泡沫细胞形成及相关基因表达的调控机制研究

Modulation of CpG-ODN on Formation of Macrophage Foam Cell and Related Gene Expression in the Early Stage of Atherosclerosis

结果：黄精多糖（1.6mL·kg-1·d-1）能显著降低高脂血症实验动物的血清TC，LDLc和Lp（a）浓度和减少主动脉内膜泡沫细胞的形成。

Results : Polyona-polysaccharose significantly reduced serum TC , LDL-C , LP ( a ) and aortic foam cells in the experimental rabbits .

对β-VLDL及修饰的LDL可引起泡沫细胞的形成作了讨论。

The fact that β - VLDL and modified LDL may lead to the formation of foam cells from macrophage was discussed .

经HFC负荷试验，血液中总胆固醇升高59～97倍，肾病变加重，出现肾小球泡沫细胞。

The HFC burden test showed 5.9-9.7 times higher concentration of total cholesterol , severe nephrosis and appearance of renal glomerulus foam cells .

初步了解儿茶酚胺类激素影响THP-1巨噬细胞源性泡沫细胞功能的细胞信号转导途径。

To investigate the cell signal transduction pathway of catecholamines induce dysfunction of THP-1 macrophage-derived foam cell .

主要观察指标：LPL和HL活性、LPLmRNA表达、HlmRNA表达、泡沫细胞形成率、动脉粥样硬化斑块形成率。

The LPL and HL activity , the LPL mRNA and HL mRNA expression , foam cell and the area of atherosclerosis plaque were detected .

体外实验证实VLDL可诱导系膜细胞变为泡沫细胞。

It was shown in vitro that VLDL also induces foam cell formation in human mesangial cells .

高浓度胰岛素（100mU/L以上）可促进ox-LDL环境中THP-1细胞向泡沫细胞转化，同时细胞LPLmRNA表达明显上调。

Insulin enhances transferring THP-1 cells to foam cell exposed to ox-LDL , it also up-regulates LPL mRNA expression in the THP-1 cell .

Ox-LDL诱导早期巨噬细胞源泡沫细胞形成和损伤中相关动力学机制研究

Study on Mechanism Associated with the Kinetics of Formation and Damage in Early Macrophage Foam Cell Induced by Oxidized Low-density Lipoprotein

MMF治疗组小鼠病变明显较轻，每个瓣叶所含泡沫细胞显著少于高脂组（P<0.001）。

Significantly less foam cells were in each valve cusp area ( 4.0 ± 2.5 ) than that of untreated group .

结果：3例疣状黄瘤中泡沫细胞CD68（KP1）和Vimentin呈强阳性表达；

RESULTS : The foam cells were strongly positive for CD68 ( KP1 ) and Vimentin .

结果：肾小球局灶节段性透明变性及间质泡沫细胞浸润在小儿原发性FSGS中是一个较为特征性的表现。

Results Focal segmental hyalinosis and intraglomerular foamy cells were characteristic of primary into FSGS for children .