沙美特罗

不对称亨利反应在（R）-沙美特罗合成中的应用

Application of asymmetric Henry reaction in the synthesis of ( R ) - salmeterol

均给予吸入沙美特罗/丙酸氟替卡松干粉剂（商品名：舒利迭，剂量：50μg/500μg）每日2次，疗程6个月。

All the patients inhaled salmeterol / fluticasone propionate dry powder ( seretide , 50 μ g500 μ g ) twice daily for six months .

结论：1.经过沙美特罗/氟替卡松的治疗后，COPD患者呼吸困难得到显著改善。

After Salmeterol / Fluticasone inhalation treatment , the COPD patients has improved on dyspnoea . 2 .

吸入沙美特罗氟替卡松对COPD稳定期患者肺功能及气道炎症的影响

Effects of Salmeterol and Fluticasone Propionate Inhalation on Pulmonary Function and Airway Inflammation in COPD Patient during Stable Period

结论对COPD患者给予沙美特罗吸入治疗能明显改善患者肺功能，缓解临床症状和提高生活质量。

Conclusion The inhalation of salmeterol for COPD can significantly improve lung function , alleviate clinic symptoms and improve life quality of the patients .

经过沙美特罗/氟替卡松的治疗后，COPD患者BODE指数显著降低。

After Salmeterol / Fluticasone inhalation treatment , the BODE index of COPD patients has been decreased obviously . 3 .

沙美特罗为选择性β2-肾上腺受体激动剂，一次吸入至少产生12h的支气管扩张作用。

Salmeterol is a selective β 2-adrenergic receptor agonist , it can produce effects at least 12 hours one time .

目的：研究舒利迭（沙美特罗/替卡松粉吸入剂，50μg/250μg）对中重度慢性阻塞性肺病（COPD）患者肺功能的影响。

Objective : To evaluate the effect of inhaled Seretide ( salmeterol 50 μ g and fluticasone propionate 250 μ g ) on lung function in patients with moderate-severe chronic obstructive pulmonary disease ( COPD ) .

支气管哮喘患者101例，随机双盲分为2组，沙美特罗组52例（男性34例，女性18例；年龄38±s10a），吸入沙美特罗50μg，bid；

One hundred and one patients with bronchial asthma were randomly divided into two groups in double-blind method . Group A ( 52 patients , M 34 , F18 ; age 38 ± s 10 a ) were treated with salmeterol aerosol 50 μ g , bid for 4 wk .

方法体外分离29例哮喘患者血小板，用流式细胞仪测定哮喘患者持续吸入沙美特罗/丙酸氟替卡松治疗前后血小板膜蛋白分子CD62P、CD40L的表达，并分析其与肺功能的关系。

Methods Platelets were isolated from 29 patients with asthma , before and after inhaled salmeterol and fluticasone 3 months , the expression rates of platelet membrane protein molecules CD62P , CD40 ligand ( CD40L ) were measured by flow cytometry .

目的探讨沙美特罗替卡松粉吸入剂（商品名舒利迭Seretide，葛兰素史克公司生产）治疗儿童哮喘的疗效及副作用。

Aim To study the curative effect and side effect of salmeterol and fluticasone propinate combined in a new powder inhalation device ( company 's product name is Seretide , GlaxoSmithKline campany produces ) on children asthma .

沙美特罗替卡松吸入剂预防急性高原反应的效果观察

Salmeterol for the Prevention of Benign form of Acute Mountain Sickness

沙美特罗的新合成路线。

Aim To develop a new synthetic route to salmeterol .

沙美特罗与丙酸氟替卡松合剂对哮喘儿童肺功能的影响

Effects of salmeterol xinafoate and fluticasone propionate on pulmonary function of asthma children

沙美特罗和沙丁胺醇气雾剂治疗哮喘患者101例的对比

Salmeterol vs salbutamol aerosol treatments in 101 asthma patients

小鼠尿中沙美特罗及其代谢物的LC/MS研究

Determination of Salmeterol and Its Metabolites in Rat Urine by LC / MS

吸入沙美特罗-替卡松治疗慢性阻塞性肺疾病的临床观察

Clinical observation of inhaling salmeterol-fluticasone in patients with COPD

吸入沙美特罗替卡松干粉剂与联合吸入二丙酸倍氯米松、沙丁胺醇气雾剂治疗成人哮喘疗效比较

Comparison of Seretide versus combination of Salbutamol and beclomethasone dipropionate in adult asthma

沙美特罗替卡松粉剂治疗支气管哮喘的疗效观察

Salmeterol and fluticasone propionate powder treatment of bronchial asthma

沙美特罗联合替卡松粉治疗咳嗽变异型哮喘临床探讨

Salmetorol and Fluticasone Power for Cough Variant Asthma

沙美特罗/氟替卡松联合应用治疗重度哮喘的临床观察

Clinical efficacy of combined salmeterol / fluticasone propionate in treatment of severe persistent asthma

结论沙美特罗替卡松干粉吸入能够改善慢性阻塞性肺疾病的肺功能。

Conclusion Salmeterol and fluticasone propionate inhalant can improve pulmonary function in COPD patients .

沙美特罗/氟替卡松治疗哮喘的临床研究

Clinical study of salmeterol / fluticasone on asthma

沙美特罗吸入剂对初进高原青年肺功能的影响

Effects of salmeterol on pulmonary function of youth exposed to high altitude in early stage

长期应用丙酸氟替卡松/沙美特罗治疗轻中度哮喘的临床疗效评价

Clinical evaluation of efficacy of fluticasone propionate / salmeterol in treatment of mild to moderate asthma

联合应用沙美特罗/氟替卡松与噻托溴铵对慢性阻塞性肺疾病肺功能的疗效

Therapeutic effect of salmeterol / fluticasone propionate combined with tiotropium bromide therapy for patients with COPD

沙美特罗/丙酸氟替卡松对哮喘儿童肺功能的改善及临床意义

The clinical significance and improvement of salmeterol / fluticasone propionate to pulmonary function of children with asthma

沙美特罗和布地奈德的脂质体/水分配系数测定及影响因素考察

Determination of liposome / water partition coefficients of salmeterol and budesonide and study on their influencing factors

吸入沙美特罗/氟替卡松治疗儿童支气管哮喘临床疗效与骨密度观察

Study the clinical curative effect and safety of inhaled salmeterol / fluticasone in curing childhood bronchial asthma

沙美特罗替卡松联合治疗儿童中重度哮喘的临床研究

Clinical study of salmeterol / fluticasone propionate combination in therapy of moderate to severe asthma in children