水通道
- 网络aquaporin;Aquaporins;Water channel;aqp
![水通道](../cache/1192150.jpg)
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水通道蛋白(Aquaporin,AQP)是一组具有同源性的内在膜蛋白家族成员,是水跨膜转运的主要分子基础。
Aquaporin ( AQP ) are a family of hydrophobic intrinsic membrane proteins that efficiently and selectively transport water . Aquaporin is the main molecular basis of water transmembrane transport .
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目的:探讨星形胶质细胞形态学观察在高通量药物筛选水通道蛋白4(AQP4)抑制剂中的应用,为脑水肿和其他水转运障碍疾病的治疗提供理论依据。
Aim : To explore the method for high throughput drug screening searching for Aquaporin 4 ( AQP4 ) inhibitor and develop a new therapeutic approach to treat brain edema .
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简并PCR检测细菌水通道蛋白基因的研究
A study of bacterial aquaporins with degenerate PCR
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充血性心力衰竭时肾脏水通道蛋白mRNA表达的改变及意义
Expression of channel protein mRNA in kidney of congestive heart failure and its significance
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脂多糖&烟雾诱导慢性支气管炎大鼠模型水通道蛋白5表达与肿瘤坏死因子α、白介素13、白三烯B4的变化
Expression of Aquaporin 5 and Changes of Tumor Necrosis Factor α, Interleukin 13 , Leukotriene B_4 in Lipopolysaccharide-Cigarette Smoking Inducible Chronic Bronchitis Rat Model
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水通道蛋白4与视神经脊髓炎的关系基于OPENGL的蛋白质相互作用可视化研究
Relationship of Aquaporin-4 and Neuromyelitis Optica ; Visualizing Protein-Protein Interaction Based on OpenGL
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LPS对鼠肺微血管内皮细胞水通道蛋白-1表达及其功能的影响
Effects of lipopolysaccharide on aquaporin-1 expression and function in rat lung microvessel endothelial cells
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肝功能衰竭大鼠脑水通道蛋白-4表达与MRDWI的相关性研究
A Correlative Study between the Expression of Aquaporin-4 and Molecular Mechanism of MR DWI after the Hepatic Failure in Rats
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ELISA法检测心力衰竭模型大鼠尿液水通道蛋白-2的变化及意义
Changes and significance of aquaporin-2 water channel protein in urinary concentration detected by ELISA in a rat model of congestive heart failure
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去铁胺干预对大鼠ICH后水通道蛋白4表达变化的影响
Effect of Deferoxamine on Aquaporin-4 Expression in a Rat Model of Intracerebral Haemorrhage
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抑制水通道蛋白1对Hep-2细胞增殖和凋亡的影响
Effect of inhibiting aquaporin-1 on proliferation and apoptosis of the Hep-2 cell
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siRNA沉默水通道蛋白4治疗创伤性脑水肿的实验研究
An experimental study of siRNA targeting aquaporin 4 treatment on cerebral edema following traumatic brain injury
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目前从哺乳动物组织中已鉴定出至少五种水通道蛋白,统称为水蛋白(aquaporin,AQP),均属于主体内在蛋白(MIP)家族的成员。
AQPs the members of major intrinsic protein ( MIP ) family .
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胃泌素对结肠癌细胞株HT-29水通道蛋白4表达的影响
Effect of gastrin on aquaporin 4 expression in human colon cancer HT-29 cell line
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大鼠脊髓损伤后脊髓水肿与水通道蛋白4(AQP-4)表达变化的研究
The Expression Changes of AQP-4 after Spinal Cord Injury of Rat
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异丙酚预处理对HK-2细胞缺氧/复氧损伤后水通道蛋白1表达的影响
Effects of Propofol Pretreatment on the AQP-1 Expression after HK-2 Cells Injured by Anoxia-reoxygenation
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目的了解急性脑出血后灶周脑组织水通道蛋白-4(AQP-4)的表达。
Objective To investigate the expression of AQP-4 after brain hemorrhage in human .
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而且,我们发现,在利妥昔单抗治疗期间,水通道蛋白4抗体滴度与CD19细胞数相关。
Moreover , AQP4-Ab titres were found to correlate with CD19 cell counts during therapy with rituximab .
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高原反应的脑病理与水通道蛋白-4(AQP4)的相关性实验研究
Study of aquaporin protein 4 with cerebral pathology and pathogenesis of high altitude response
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水通道蛋白1(AQP1)在人类胎盘胎膜中的分布及表达
Expression and Distribution of Aquaporin 1 in Human Placentas and Fetal Membranes
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水通道蛋白-2(aquaporin-2)在大鼠内耳的定位及其意义探讨
The Orientation and Its Significance of Aquaporin-2 in the Rat Inner Ear
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大鼠创伤性脑水肿早期水通道蛋白AQP-4的表达及意义
Expression and Its Significance of the AQP-4 during Early Period Following Traumatic Brain Edema in Rats
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脑损伤后12h、24h、48h给药,水通道蛋白4的表达和脑组织含水量差异无显著性(P>0.05)。
After 12 , 24 and 48 hours brain damage , the expression of aquaporin 4 and BWC had insignificant difference ( P > 0.05 ) .
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水通道蛋白(aquaporin,AQP)是一族细胞膜上选择性高效转运水分子的特异孔道。
Aquaporins ( AQP ) are a family of hydrophobic intrinsic membrane proteins that efficiently and selectively transport water .
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目的:观察水通道蛋白-4(AQP-4)对脑血吸虫病脑血管通透性的作用。
Objective : To investigate function of aquaporin-4 ( AQP-4 ) on vascular permeability in encephalopathy of schistosomiasis .
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目的建立较为稳定的定量检测尿液水通道蛋白-2(AQP2)的酶联免疫吸附测定(ELISA)法。
Objective To develop an efficient and stable enzyme-linked immunosorbent assay ( ELISA ) for detecting urinary aquaporin-2 ( AQP2 ) water channel protein .
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目的:检测水通道蛋白(AQP)-1,3在豚鼠耳蜗及内淋巴囊中的表达情况。
Objective : To detect the expression of Aquaporin-1,3 in the cochlea and endolymphatic sac of guinea pig .
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各种导致脑水肿的因素可能最终通过影响水通道蛋白4(AQP4)而发挥作用。去铁胺,一种强有力的铁螯合剂,可减轻脑出血后的脑水肿形成。
Deferoxamine ( DFO ) - a potent iron chelator can relieve brain edema resulted from ICH and hemoglobin .
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水通道蛋白(AQPs)是细胞膜上特异性转运水的孔道。
Aquaporins ( AQPs ) are membrane water channels , which selectively transport water across cell plasma membranes .
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目的观察大鼠肺泡Ⅱ型上皮细胞水通道蛋白1(AQP1)的表达。
Objective To explore the expression of aquaporin-1 ( AQP1 ) in rat alveolar type ⅱ cells .