次级溶酶体

结果提示，较高SiO2剂量所致的巨噬细胞损伤，并非完全是SiO2粉尘与次级溶酶体膜直接相互作用的结果。

The results showed that at higher dose of silica , macrophages injury can not be completely the result of the direct interaction between silica and secondary lysosome membrane of macrophages .

当煤粒吞噬体进入胞浆后，常被多个溶酶体接触包围，形成次级溶酶体。

In vital cells , within a few hours , numerous lysosomes clustered around the phagosomes which contained the dust particles , and then the secondary lysosome was formed .

次级溶酶体和小颗粒呈MPO强阳性。

The secondary lysosomes and the small granules are strongly positive to MPO .

Po1ystyrene胶乳颗粒吞噬百分数和吞噬指数亦增高。透射电镜观察，2.5%DMSO处理的、核质比值小于0.5的ARS细胞内，细胞器丰富，Golgi复合体发达，次级溶酶体增多。

Under EM , 2.5 % DMSO treated ARS cells with nucleocytoplasmic ratio less than 0.5 exhibited abundant cytoplasmic organelles , developed Golgi complex and secondary lysosomes .

0.4ml组的次级溶酶体数量和弓状核细胞体上含颗粒囊泡的轴体突触数目均增加，该两项分别与对照组比较，差异有显著性（P值均<0.01）。

The amount of lysosomes and axo-somatic synapses-containing granular vesicles in the cells increased in 0.4ml experimental group , and there was a statistically significant difference ( p < 0.01 ), compared with the control group .

溶酶体增多，体积增大，内含粗糙颗粒，可见不同阶段的初级和次级溶酶体。

Lysosome increased and was larger and full of rough granules .

肺泡巨噬细胞次级溶酶体明显增多。

In alveolar macrophage the increasing secondary lysosomes are seen .

电镜观察显示：受损伤细胞内含有大量吞噬铁质的次级溶酶体，细胞有不同程度的变性和坏死。

Observation of the electron microscope showed that there were a lot of secondary lysosomes contained ferri in damaged cells with degeneration and necrosis in varying degrees .

超微结构观察显示，高温组小肠上皮细胞内线粒体、次级溶酶体、转运小泡数量增多，说明细胞通过代谢增强，促进损伤的修复来对抗高温的影响。

Ultrastructural observation showed that in the high temperature group , the intestinal epithelial cell mitochondria , secondary lysosomes and transitional vesicles increased in the number , which showed the cells respond to high temperature by enhancing metabolism and promoting the repair of damage .

在产后第7～13天之间，巨噬细胞数量明显增多，胞质中线粒体、粗面内质网以及初、次级溶酶体等细胞器丰富；

Within the days 7 to 13 postpartum , macrophage obviously increased in number , the cellular organs , such as , mitochondria and rough endoplasmic reticulum ( R.ER ) and first and / or second lysosome were in a large number in the cytoplasm ;