梗阻性肾病

目的：探讨甘草酸18α体对梗阻性肾病大鼠肾间质中NFκB表达的影响。

AIM : To investigate the effects of glycyrrhizin-18 α on the expression of nuclear factor - κ B in the renal interstitium of rats with obstructive nephropathy .

目的从蛋白质水平研究转化生长因子（TGFβ1）在梗阻性肾病中所起的作用及血管紧张素转化酶抑制剂-西那普利（Cilazapril）对其表达的影响。

Objective To evaluate the role of transforming growth factor β 1 ( TGF β 1 ) in obstructive nephropathy and the effect of an angiotension converting enzyme ( ACE ) inhibitor , cilazapril .

甘草酸18α体调节梗阻性肾病大鼠肾间质中CTGF和TGF-β1表达的实验研究

Effects of glycyrrhizin-18 α on expressions of CTGF and TGF - β 1 in renal interstitium in rats with obstructive nephropathy

结论：PGE1可以抑制TGF-β1、CTGF的表达，减轻肾间质纤维化，从而防治梗阻性肾病。

Conclusion : PGE1 could alleviate tubulointerstitial fibrosis through inhibiting the expressions of CTGF and TGF - β 1 in tubulointerstitium .

结论甘草酸可能通过下调梗阻性肾病大鼠肾间质CTGF和TGFβ1的表达，抑制肾间质纤维化的发生。

Conclusion Glycyrrhizin-18 α may inhibit renal interstitial fibrosis in rats with obstructive nephropathy by down-regulating the expressions of CTGF and TGF - β 1 in the rat renal interstitium .

结论：OPN、MCP1蛋白在梗阻性肾病大鼠肾组织表达明显增加介导炎症过程，参与肾间质纤维化。

Conclusion : The protein of OPN and MCP-1 is increased significantly in the obstructed kidney , which may cause renal fibrosis .

梗阻性肾病细胞凋亡的药物调控研究进展

Progress in research on drug modulation of apoptosis in obstructive nephropathy

梗阻性肾病肾纤维化与血清中Ⅲ型胶原变化的相关性研究

Relationship between collagen type ⅲ in serum and renal fibrosis in obstructive nephropathy

红花注射液对梗阻性肾病解除梗阻后肾功能恢复的机制研究

Renal recovery effects of safflower injection on patients with obstructive nephropathy and its mechanism

梗阻性肾病的磁共振肾功能成像

Obstructive nephropathy : MRI functional imaging of kidney

慢性梗阻性肾病进展的相关因素分析

Risk Factor of Progression of Obstructive Nephropathy

塞来昔布对梗阻性肾病大鼠肾脏作用的实验观察

Experimental observation of celecoxib on obstructive nephropathy

目的进一步探讨慢性梗阻性肾病病程进展的危险因素。

Objective : To study the risk factors of the progression of chronic obstructive nephropathy .

前列腺癌的死因主要是癌肿早期转移、梗阻性肾病。

The main causes of death of the cancer were bone metastasis and obstructive nephropathy .

转化生长因子β1与梗阻性肾病肾小管间质纤维化关系的研究

Clinical Study on the Relationship between Transforming Growth Factor Beta-1 and Tubulointerstitial Fibrosis in Obstructive Nephropathy

转化生长因子-β1在梗阻性肾病大鼠肾小管间质纤维化中的作用

Roles of transforming growth factor β 1 in renal tubule interstitial fibrosis in obstructive nephropathy rats

梗阻性肾病

Views about Obstructive Nephropathy

目的：探讨在新西兰大白兔梗阻性肾病的动物模型上解除梗阻后，红花注射液对促进肾功能恢复的机制。

Objective : To study the renal recovery effects of Safflower injection on patients with obstructive nephropathy and its mechanism .

10例梗阻性肾病，双肾增大，肾盂、肾盏、输尿管明显积水。

There were enlargement of double kidneys and dropsy of renal pelvis , renal calyces and ureter in 10 cases of patients with obstructive nephrosis .

原发病：糖尿病肾病26例，肾炎33例，高血压肾病18例，梗阻性肾病14例，多囊肾3例。

Primary disease : diabetic nephropathy in 26 cases , 33 cases of nephritis , hypertensive nephropathy in 18 cases , 14 cases of obstructive nephropathy , polycystic kidney disease in 3 cases .

终末期肾脏疾病透析患者主要病因为慢性肾小球肾炎（52.0%），其次为糖尿病肾病（16.0%），高血压肾病（13.2%），梗阻性肾病（9.0%）；

Main etiological factor of ESRD patients were chronic glomerulonephritis ( CGN )( 52.0 % ), followed by diabetic nephropathy ( 16.0 % ), hypertensive nephropathy ( 13.2 % ), and obstructive nephropathy ( 9.0 % ) .

而年龄、病程、积水程度、尿路感染、复杂性尿路梗阻度等，可能对慢性梗阻性肾病进行性肾损害有影响。

Age , course of disease , degree of hydrocele and urinary tract infection may increase the risk of progression of chronic obstructive nephropathy .