柠烯

目的探讨右旋柠烯（Dlimonene）诱导人胃癌细胞株凋亡作用的机制。

Objective To investigate the apoptosis effect induced by D limonene on BGC 823 gastric cancer cells .

在碳氢化合物中以柠烯、γ萜品烯为主要成分；而在含氧化合物中主要是沉香醇、α萜品醇、百里酚以及一些脂肪族醛。

Among 71 identified compounds , there were 21 hydrocarbons which were mainly limonene and γ - terpinene , and 50 oxygenated compounds in representative of linalool , α - terpineol , thymol and aliphatic aldehydes .

右旋柠烯诱导人白血病HL-60细胞凋亡及其机制的研究

Study on the mechanism of D-limonene in inducing Human Leukemia HL-60 cell apoptosis in vitro

方法24只裸鼠乳腺原位种植人乳腺癌细胞株MDA-MB-435，建立乳腺癌模型，分成模型对照组、右旋柠烯组和5-氟尿嘧啶（5-FU）组。

Methods Human breast cancer cell lines MDA-MB-435 were implanted into the mammary fat pad of 24 female nude mice to establish breast cancer model .

右旋柠烯（d-limonene）是中药橘皮中提纯的单体成份，属于天然单萜烯类化合物。

D-limonene is a monomer extracted from traditional Chinese medicine citrus peel , and is a kind of natural monoterpene component .

结论：右旋柠烯可以抑制HL60细胞增殖并可以诱导其凋亡，其作用机理与下调细胞内的Bcl2蛋白的表达有关。

Conclusion : D-limonene could induce the apoptosis of HL-60 , the mechanism was related to the change of bcl-2 expression .

结果：右旋柠烯组乳癌生长和淋巴结转移受到抑制，LMVD降低，VEGF-C表达下调。

Results : In d-limonene group , the tumor growth and metastasis to lymph node were significantly inhibited ; LMVD and VEGF-C expression were decreased notably compared with that of in model group .

右旋柠烯对实验性乳腺增生症的影响

Effects of d-limonene on experimental mammary glands hyperplasia in rat

右旋柠烯抗胃癌转移机制实验研究

The Molecular Mechanism Study of D-limonene on Gastric Cancer Metastasis

右旋柠烯对裸鼠人乳腺癌模型淋巴转移的抑制作用

Effects of d-limonene on the lymphatic metastasis in nude mice breast cancer model

右旋柠烯乳剂对人胃癌移植瘤生长和转移的抑制作用

Inhibition of growth and metastasis of human gastric cancer implanted in nude mice by d-limonene

右旋柠烯诱导人胃癌细胞凋亡

D-limonene induces apoptosis of gastric cancer cells

金柚外黄皮中挥发性成分以柠烯碳氢化合物为主体成分，其中柠檬烯含量占粗精油的84.07%，金柚内白皮则以十八碳二烯酸、棕榈酸和七聚氧化乙烯为主体成分。

There were volatile compounds , mainly limonene , accounted for 84.07 % in the outer yellow peel , while there were mainly octadecadienoic acid , hexadecanoic acid , and ethylene oxide heptamer in the inner white peel .