抗癫痫药物

经抗癫痫药物治疗控制发作癫痫患者血清SIL-2R含量减低，与对照组无差异（P＞0.05）。

When epilepsy was controlled with AEDs treatment , the patients had lowered levels of serum SIL-2R without difference with control group ( P > 0 . 05 ) .

细胞色素P4503A基因表达调控及与抗癫痫药物的关系

Expression and Regulatory of Cytochrome 450 enzymes and relation with AEDS

HPLC法同时测定多种抗癫痫药物的血清浓度

Content determination of serum concentrations in a variety of antiepileptic drugs by HPLC

HPLC法测定患者脑组织中4种抗癫痫药物浓度

Determination of Four Kinds of Antiepileptic Drugs Concentration in Human Brain Tissue by HPLC

实际上，和GABAAR一样，GABA转运体已经是一些抗癫痫药物的靶点。

Indeed , besides GABA_AR , GABA transporter has been another target for antiepileptic drugs .

细胞色素P450酶系与抗癫痫药物的代谢

Cytochrome P450 Enzyme System and Antiepileptic Drug Metabolism

杏仁核点燃癫痫大鼠IGF-1和nNOS的表达及抗癫痫药物的影响

IGF-1 and nNOS Expression in the Amygdala Kindled Rats and the Effects of Antiepilepsy Drugs

本组SE患儿的可能诱因为：停用抗癫痫药物8例，急性非中枢神经系统感染6例，低钙血症1例。

Potential causes of SE were with drawing AED in 8 cases , acute non-central system infection in 6 cases and hypocalcemia in as case .

BAEP改变受发作频率、抗癫痫药物（AEDs）的影响。

BAEP were effected by the frequency of seizure and anti-epileptic drugs ( AED_S );

为寻找新的抗癫痫药物，合成了6个（E）-3,4,5-三甲氧基肉桂酰胺（1a～f）和4个α-溴代衍生物（12a，b）。

In the search for a new anticonvulsant agent , six ( E ) - 3,4,5-trimethoxy-cinnamides ( 1a-f ) and four of their α - bromo-derivatives ( 12a , b ) were synthesized .

本文对服用抗癫痫药物达1～1.5年的78例患儿进行了治疗药物监测（TDM）、血生化及放射学骨矿含量（BMC）等定量指标的观察研究。

Treatment determine medicine , biochemistry of blood and content of bone mineral by radiology were studied in 78 sick children who took antiepilepsy drugs for 1-1.5 years .

癫痫的治疗主要是用药物控制发作，合理科学地应用抗癫痫药物（Antiepileptics，AEDs），70%～80%癫痫患者可以得到控制。

Now 70-80 percent seizure can be controlled by the rational and scientific use of antiepileptics ( AEDs ) .

进一步对其功能的研究发现，多药转运体是一类ATP结合蛋白质超家族，能够识别多种作用机制不同的抗癫痫药物，能够主动将药物泵出到血脑屏障以外。

To investigate its function find that multi-drug transporters are ATP-binding cassette superfamily , they can accept a wide range of antiepileptic drugs with different mechanisms as their potential substrates , and actively efflux drugs out of the brain .

结论Jeavons综合征由于复杂的症状学和抗癫痫药物的影响所致的脑电图变化的遮蔽，常导致漏诊，Video-EEG对明确诊断有重要价值。

Conclusion Jeavons syndrome is liable to underdiagnosis due to the subtle clinical semiology and the masking of EEG changes by antiepileptic drugs . Video-EEG analysis is often needed for confirmative diagnosis of jeavons syndrome .

方法：对服用卡马西平及联合用其他抗癫痫药物的51例癫痫患儿，用荧光偏振免疫法（FPIA）监测其血药浓度，并结合疗效进行统计分析。

Methods : The drug serum concentration of 51 epileptic children including administrating carbamazepine alone or associated with other epileptic drugs were determined by fluorescence polarization immunoassay ( FPIA ) . The results were processed with statistics , linking with curative effect .

与传统抗癫痫药物作用于离子通道或兴奋-抑制性神经递质系统不同，其抗癫痫机制可能是通过与脑内突触囊泡蛋白SV2A结合而发挥作用。

It is approved in 2007 in China . Unlike other traditional AEDs which act on the ion channels or activate the Inhibitory Neurotransmitter system , it produces its effect by binding to synaptic vesicle protein 2A ( SV2A ), an integral membrane protein located on synaptic vesicles .

广州市精神病院门诊抗癫痫药物利用分析

Use of Antiepileptic Drugs in the Outpatient of Guangzhou Mental Hospital

采用单药治疗的癫痫患者中52.82%的患者使用的是传统抗癫痫药物，44.46%的患者使用的是新型抗癫痫药物。

52.82 % patients of single-drug treatment are using conventional AEDs .

210例抗癫痫药物不良反应病例文献分析

Literature Review of 210 Cases of ADRs by Anti epileptic Drugs

抗癫痫药物致儿童骨损害的常用检测指标

Indexes of Detecting Changes of Bone in Children with AEDs Therapy

抗癫痫药物过敏反应综合征11例分析

Antiepileptic drug hypersensitive syndrome : clinical analysis of 11 cases

抗癫痫药物对儿童骨代谢的影响

The Effect of Antiepileptic Drugs on Bone Metabolism in Children

迷走神经刺激术后血浆抗癫痫药物浓度未见明显改变。

No change in plasma concentration of AEDs was observed .

三种常用抗癫痫药物对儿童注意力的影响

Effect of three kinds of common antiepileptic drugs on attention

抗癫痫药物对大鼠记忆和学习功能影响的研究

The Study of antiepileptic drags affect function of study and memery on rats

抗癫痫药物不良反应的针灸治疗

Acupuncture and Moxibustion Therapy in counteracting the side effects of Anti Epileptic Medicine

回顾性分析357例次小儿抗癫痫药物血药浓度

Antiepileptic drug serum concentration analysis : Retrospective study of 357 children 's cases

根据患者用药的不同将其分成不同的抗癫痫药物组。

Patients were divided into different antiepileptic drug groups .

固相萃取用于血浆中抗癫痫药物的提取

Extraction of the antiepilepsy drugs in plasma by SPE

抗癫痫药物引起重型药疹33例临床分析

Clinical analysis on 33 patients with severe drug eruption caused by antiepileptic drugs