抗中性粒细胞抗体

方法收集92例有肾活检资料的LN病人血清，分别以正常人中性粒细胞、原幼粒细胞提取物为抗原，用westernblot法检测LN病人血清中的抗中性粒细胞抗体。

Methods Sera were collected from 92 renal biopsy proven LN patients . Normal neutrophils and white cells from patients with chronic granulocytic leukemia ( CGL ) were used as antigens in Western blot analysis to detect autoantibodies in the LN sera .

狼疮肾炎患者血清抗中性粒细胞抗体和靶抗原的研究

Antineutrophil autoantibodies and their target antigens in lupus nephritis

目的探讨抗中性粒细胞浆抗体（ANCA）在妊高征患者内皮细胞损伤中的作用及可能机理。

Objective To evaluate the possible role of ANCA in the endothelial cell damage of PIH .

小血管炎，原发性；肺损害；HRCT；抗中性粒细胞胞浆抗体；

Small vessel vasculitis , primary ; Pulmonary lesions ; HRCT ; Antineutrophil cytoplasmic antibody ;

方法对23例MPA的临床、病理改变进行分析归纳，并将抗中性粒细胞胞质抗体（ANCA）（+）和ANCA（-）的MPA患者进行比较。

Method The clinical pathological changes of 23 MPA patients were analyzed and the patients with positive ANCA were compared with those with negative ANCA .

目的为了解老年人抗中性粒细胞胞浆抗体（ANCA）相关性小血管炎所引起的多器官损害的临床表现。

Objective To analyze the multiple organ damage in elderly patients with antineutrophil cytoplasmic antibody ( ANCA ) related vasculitis .

阻断IgG-FcγR结合短肽在抗中性粒细胞胞浆抗体促进中性粒细胞凋亡中的作用

Inhibitory effect of an small peptide able to interfere with Fc γ - receptor recognition on ANCA-accelerated apoptosis of neutrophils

目的：了解儿童抗中性粒细胞胞浆抗体（ANCA）相关原发性小血管炎&韦格纳肉芽肿的临床、病理特点及发病机制。

Objective : To study the clinical and pathological characteristics of ANCA related idiopathic small vessel vasculitis in children-Wegener 's granulomatosis .

目的研究溃疡性结肠炎（UC）患者的人类白细胞抗原DR（HLADR）基因分型，并分析其与抗中性粒细胞胞浆抗体（ANCA）及疾病分型的关系。

Objective To study HLA DR genotyping and to analyze the relationship among HLA DR genotyping , antineutrophil cytoplasmic antibodies ( ANCA ), clinical classification of ulcerative colitis ( UC ) .

目的探讨抗中性粒细胞胞质抗体（ANCA）在系统性红斑狼疮（SLE）伴肺间质病变（ILD）中的临床意义。

Objective To study the diagnostic value of antineutrophil cytoplasmic antibodies ( ANCA ) on interstitial lung disease ( ILD ) in systemic lupus erythematosus .

目的探讨以肾脏受累为主要表现的抗中性粒细胞胞浆抗体（ANCA）相关性小血管炎的早期诊断及适时合理治疗。

Objective To investigate the early diagnosis and proper treatment of antineutrophil cytoplasmic antibody ( ANCA ) - associated small-vessel vasculitis with renal involvement .

用间接免疫荧光法检测抗中性粒细胞胞浆抗体（ANCA），病理组织切片技术观察病变。

Anti-neutrophil cytoplasmic antibody ( ANCA ) was detected with indirect immunofluorescence , and the pathological changes were investigated with pathological tissue section technique .

目的：研究抗中性粒细胞胞浆抗体（ANCA）的检测对血管炎诊断的意义及中药对其影响。

Objective To study the clinical significance of antineutrophil cytoplasmic antibodies ( ANCA ) and the impact of traditional herbs in patients with vasculitis .

方法对我科近10年来经肾活检确诊的100例新月体性肾炎进行回顾性分析，对患者血清进行抗中性粒细胞胞浆抗体（ANCA）和抗肾小球基底膜（GBM）抗体的检测。

Methods 100 patients with renal biopsy proven crescentic glomerulonephritis were retrospectively studied , whose serum ANCA and anti-GBM antibody were measured by ELISA .

目的分析抗中性粒细胞胞浆抗体（ANCA）阳性的狼疮性肾炎（LN）患者的临床特点，探讨ANCA检测的临床意义。

Objective To analyze the clinical features of patients with lupus nephritis positive for antineutrophil cytoplasmic antibodies ( ANCA ) and explore the clinical implications of ANCA detection .

目的分析儿童丙基硫氧嘧啶（PTU）致抗中性粒细胞胞浆抗体（ANCA）阳性新月体肾炎的临床、病理特点及发病机制。

Objective To study the clinical and pathological characteristics of crescentic glomerulonephritis with positive anti-neutrophil cytoplasmic antibody ( ANCA ) induced by propylthiouracil .

目的：提高临床对丙硫氧嘧啶（PTU）引起抗中性粒细胞胞浆抗体（ANCA）相关小血管炎的认识。

Objective : To improve the knowledge on propythiouracil ( PTU ) - induced antineutrophil cytoplasmic antibody ( ANCA ) - associated vasculitis .

回顾性分析10例丙基硫氧嘧啶（PTU）相关的抗中性粒细胞胞浆抗体（ANCA）阳性患者的临床资料。

A retrospective analysis was carried out in 10 antineutrophil cytoplasmic antibody ( ANCA ) positive patients treated with propylthiouracil ( PTU ) .

前言：目的：探讨应用抗中性粒细胞胞浆抗体（ANCA）检测血管炎患者方法及意义。

Objective : To evaluate the significance of determination of serum anti Neutrophil Cytoplasmic antibody in diagnosis of Vasculitis .

目的研究丙基硫氧嘧啶（PTU）引起的抗中性粒细胞胞质抗体（ANCA）阳性小血管炎的临床病理表现及其靶抗原。

Objective To study the clinicopathological manifestations and target antigens of propylthiouracil ( PTU ) induced antineutrophil cytoplasmic antibody ( ANCA ) positive vasculitis .

临床表现复杂且缺乏特异性，往往没有肾小球肾炎、肺损害及抗中性粒细胞胞浆抗体（ANCA）。

The clinical situations are complex and lack of specificity . It is charactered by lack of glomerulonephritis , lung lesions and antineutrophil cytoplasmic antibodies ( ANCA ) .

目的了解抗中性粒细胞胞质抗体（ANCA）阳性检出率、流行病学特点及其靶抗原。

Objective To study the detectable rate of antineutrophil cytoplasmic antibodies ( ANCA ) in Chinese patients with clinical suspected small vessel vasculitis , and the target antigens .

目的探讨儿童抗中性粒细胞胞浆抗体（ANCA）相关性小血管炎的临床表现、血清ANCA和肾脏病理检查特征以及其治疗转归情况。

Objective Antineutrophil cytoplasmic antibody ( ANCA ) associated small vasculitides ( ASV ) are rare in children and often complicated in clinical manifestations and have very poor prognosis .

其中1例患者抗中性粒细胞胞浆抗体（P-ANCA）阳性且该患者合并有肾脏损害。

Anti-neutrophil cytoplasmic antibodies ( P-ANCA ) of the other one is positive . ANCA-positive easily combined with damage of kidney .

结果患儿均以肉眼血尿、蛋白尿起病，伴肾功能不全，1例抗中性粒细胞胞浆抗体（ANCA）阳性，肾活检提示肾血管炎改变、肾血管坏死及新月体形成；

Results Two cases presented with gross hematuria , proteinuria and renal dysfunction . One case with antineutrophil cytoplasmic antibody ( ANCA ) - positive and vasculitis lesion with cresent in the renal biopsy ;

目的观察丙基硫氧嘧啶（PTU）引起的抗中性粒细胞胞浆抗体（ANCA）相关小血管炎患者活动期和缓解期血清中抗MPO抗体IgG亚型的分布并探讨其意义。

Objective To investigate the distribution of IgG subclass of anti myeloperoxidase ( MPO ) antibodies , a kind of antineutrophil cytoplasmic autoantibody ( ANCA ), in sera from patients with propylthiouracil ( PIU ) induced vasculitis .

活动期系统性红斑狼疮患者血清抗中性粒细胞胞浆抗体的临床意义

Significance of Serum Antineutrophil Cytoplasmic Antibodies in Active Systemic Lupus Erythematosus

系统性红斑狼疮患者中抗中性粒细胞胞质抗体和细胞因子的关系

Correlation between antineutrophil cytoplasmic antibodies and cytokines in systemic lupus erythematosus

丙基硫氧嘧啶引起抗中性粒细胞胞质抗体相关小血管炎并非药物性狼疮

Vasculitis associated with propylthiouracil-induced antineutrophil cytoplasmic antibody is not drug induced lupus

抗中性粒细胞胞浆抗体及其靶抗原检测与肾脏疾病的临床研究

Study on correlation between Antineutrophilic cytoplasmic antibodies and renal diseases