抗原肽
- 名antigen peptide
![抗原肽](../cache/1167801.jpg)
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目的研究MAGE3抗原肽对肝细胞癌(HCC)患者进行免疫治疗的可行性。
Objective To explore the possibility of immune therapy for hepatocellular carcinoma ( HCC ) with MAGE-3 antigen peptide ( FLWGPRALV ) .
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目的探讨通过树突状细胞(DC)提呈途径降低肿瘤抗原肽用量的可行性,了解热休克蛋白70(Hsp70)和抗原肽修饰DC作用的特点。
Objective To investigate the feasibility of reduction in tumor antigen peptide dose by dendritic cell ( DC ) presenting so as to elucidate the characteristics of modifying DC by heat shock protein ( Hsp70 ) and antigen peptide .
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结论DC提呈抗原肽激活淋巴细胞的途径能够有效杀伤肿瘤。
Conclusions DC-presenting pathway to activate lymphocytes could kill the tumor effectively .
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抗原肽、DC及CD4~+T细胞对CD8~+T细胞免疫应答的影响
Influence of Peptides , DCs and CD4 ~ + T Cells on CD8 ~ + T Cell Activation
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目前在抗肿瘤免疫治疗中,最常用的负载DC的方式有应用抗原肽和全抗原两种。
DC vaccines are always made by been pulsed with tumor peptide or complex antigen in anti-tumor immunotherapy .
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点突变p53抗原肽的预测及其与MHCⅠ类分子的结合
Prediction and binding of a mutant p53 peptide to MHC class I molecule
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HBV抗原肽冲击的DC对慢性乙型肝炎及HBV携带者的免疫治疗作用
Efficacy of immunotherapy using autologous dendritic cells pulsed with hepatitis B surface antigen in patients with chronic hepatitis B
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目的:可溶性HLAA2抗原肽复合物的体外折叠复性与生物素化。
AIM : To refold and biotinylate HLA A2 peptide complex in vitro .
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胆管癌抗原肽对转染全长野生型p53的树突状细胞免疫功能的影响
Effects of bile duct cancer peptide on immune response of dendritic cells transfected with full-length wild type P53
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SLAⅡ类基因的多态性和抗原肽结合位点密切相关,这些位点能结合处理过的抗原,然后递呈给T细胞。
SLA class ⅱ polymorphism was related to the antigenic peptide binding sites .
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同种CTL识别表位的抗原肽非依赖性现象
Antigenic Peptide-independent Phenomena of the Epitope Recognized by Allogeneic CTL
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MAGE-12的新B细胞表位抗原肽的设计、合成及免疫原性研究
Symthesis and identification of a new B-cell epitope of tumor antigen MAGE-12
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MHCⅠ类分子及其结合抗原肽的研究进展
The Research Advances in MHC Class ⅰ Molecules and Their Binding Antigenic Peptides
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抗原肽与MHC分子相互作用的QSAR模型研究
QSAR Model Study of Interaction between Peptides and MHC Molecules
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结论同种反应性CTL对同种MHC分子的识别不依赖抗原肽。
Conclusion Allogeneic recognition of alloreactive CTLs to MHC molecules was antigenic peptide-independent .
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GAD抗原肽抗体介导免疫耐受对NOD小鼠糖尿病治疗研究
GAD-grafted IgG Molecule Induces Immune Tolerance to Treat Diabetes in NOD Mice
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目的检测安徽省1型糖尿病患者的抗原肽相关运载蛋白体(Transporterassociatedwithantigenprocessing,TAP)基因位点多态性。
Objective To understand the polymorphisms of transporter associated with antigen processing ( TAP ) genes in patients with Type 1 Diabetes mellitus in Anhui .
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Mage-A3抗原肽负载DC过继免疫治疗乳腺癌的实验研究
Immunotherapy of dendritic cells loaded with the peptide derived from mage-a_3 on mice breast cancer
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值得注意的是,疱疹病毒颗粒在宿主细胞内体中装配,而内体恰为MHcII分子与抗原肽结合的部位。
It is noteworthy that the Herpes virus assembles viral particles in endosomes , where antigenic peptides bind to MHC II molecules .
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目的:体外折叠形成可溶性HLAG1抗原肽复合物,并研究其生物学功能。
AIM : To form soluble HLA-G 1-peptide complex by refolding in vitro , and study its immune function .
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MHCI类分子与抗原肽的结合具有MHC等位基因特异性。
The combination between MHC class I molecule and antigenic peptide express the MHC allele - specificity .
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Graves甲亢肝损害与抗原肽运载体1基因多态性关联性的研究
The Association between Graves ' Disease of Hepatic Injury and Polymorphism in Transporter Associated with Antigen Processing 1 Gene
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HLA-A2相关肝癌抗原肽的初步研究
Study on HLA-A2 associated antigen peptide from human hepatocellular carcinoma
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人食管癌Eca-109细胞Mr小于3000膜蛋白肿瘤抗原肽的筛选
Screening of tumor antigenic peptides in membrane antigen with M_r less than 3000 of human esophageal carcinoma Eca-109 cell line
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目的探讨GAD抗原肽抗体诱导特异性免疫耐受对IDDM糖尿病的基因治疗。
Objective Gene therapy with GAD-IgG tolerogens that induces specific tolerance to IDDM .
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微囊化CEA抗原肽表位/IL-18基因重组细胞疫苗的构建及其免疫学活性的研究
The Study on the Construction and the Immunological Activity of the Tumor Vaccine Combined with CEA-epitopes and IL-18 in Microencapsulated Cells
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利用HLAI类分子与单链抗体的融合可将特定的抗原肽/HLA复合物加载到目的细胞表面,目前研究主要应用于加载HLA分子到肿瘤表面。
The fusion of HLA class I molecule and single-chain antibody can attach the peptide / HLA complex to target cells like tumor cells .
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CTL和DC-抗原肽嵌合疫苗已应用于临床并取得了显著效果。
Now the application of CTL and " DC - peptide " vaccine in the clinic show much effect .
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弱酸洗脱提取的肿瘤抗原肽致敏的树突状细胞对CTL的体内外激活效应
In vivo and in vitro activation of CTL by murine dendritic cells pulsed with acid eluted tumor antigen peptides
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能与MHC分了绑定结合的抗原肽,被称为MHC分子亲和肽。MHC分子亲和肽的精确预测对于免疫学家和医学工作者意义重大。
Accurate prediction of such peptides that can bind to MHC molecules is of great significance for immunologists and biomedical staff .