慢性炎症

动脉粥样硬化是一个慢性炎症过程，NF-κB在其中发挥重要作用。

Atherosclerosis is a chronic inflammation course , NF κ B , a kind of nuclear transcription factor , plays an important role .

研究背景与目的肝脏肿瘤，特别是肝细胞肝癌（Hepatocellularcarcinoma，HCC），与肝脏的慢性炎症密切相关。

Background and Aims : Liver tumor , especially hepatocellular carcinoma ( HCC ), is closely associated with chronic inflammation .

结果：在慢性炎症胰岛中，B细胞缺陷显著延缓糖尿病发展。

Results : B cell deficiency significantly delayed diabetes development in chronically inflamed islets .

银屑病（psoriasis）是临床常见的慢性炎症性皮肤病，其发病机理尚未明确。

Psoriasis is a chronic inflammatory skin disease whose pathogenesis remains unclear .

COPD以遍及气道、肺实质和肺血管的慢性炎症为特征。

COPD is charactered on chronic inflammatory throughout airway lung parenchyma and pneumoangiogram .

VEGF的表达位于上皮细胞、血管内皮细胞及部分慢性炎症细胞；

The expression of VEGF was located in epithelial cells , vascular endothelial cells and some chronic inflammatory cells .

慢性炎症中持续的氧化应激导致DNA损伤并抑制损伤后修复。致使抑癌基因失活；

Sustained oxidative stress in the process of chronic inflammation leads to DNA damage and inhibition on its repair , resulting in inactivation of tumor suppressor genes .

MHD患者动脉粥样硬化与慢性炎症及营养不良的关系

The relationship of AS with chronic inflammation and malnutrition in MHD patients

目的：探讨胃的慢性炎症、肠上皮化生、异型增生、癌与DNA指数（DI）及倍体分布的关系。

Purpose To study the correlation between gastritis , intestinal metaplasia , dysplasia , carcinoma and DNA index ( DI ), ploidy classes .

研究背景：银屑病（Psoriasis）是一种常见的慢性炎症性皮肤病，病情顽固，且发病率在逐年增高。

Background Psoriasis is a kind of common chronic inflammatory skin disease with increasing incidence year by year .

银屑病（Psoriasis）是一种以表皮过度增生和真皮慢性炎症反应为特征的常见皮肤病。

Psoriasis is a common skin disease characterized by over hyperplasia of epidermis and chronic inflammatory reaction of corium .

病理学检查：B组术后2周局部组织以急性化脓性炎症为主，4周时以肉芽组织增生和纤维组织形成的慢性炎症反应为主；

Pathological changes : In the Group B , the main pathological changes were acute suppurative inflammation after two weeks , and chronic inflammation with hyperblastosis of granulation and fibroplasias after four weeks .

电针治疗CIA大鼠慢性炎症及对COX-2的选择性抑制作用

Therapeutic Effect of Electroacupuncture on Chronic Inflammation in Collagen-induced Arthritic Rats and Its Selective Inhibitory Action on COX-2

结果显示：宫颈癌组织中P－糖蛋白表达阳性率为40.0%。而宫颈慢性炎症和大致正常宫颈组织则无一例表达阳性。

The results showed that the positive rate of the expression of p-glycoprotein in cervical cancer was 40.0 % , while there was no expression of it in the chronic cervicitis and approximately normal control .

这些情况可能归因于刺激产生抗CCP抗体的慢性炎症。

This association may be attributed to chronic inflammation that stimulates the production of anti-CCP antibodies .

A、B、C3组子宫内膜均无慢性炎症改变，D组8例存在慢性子宫内膜炎改变，与A、B、C组差异有显著性（P＜0.05）。

There was no case with chronic endometritis in A , B , C groups , but there were eight cases with chronic endometritis in D group ( P < 0.05 ) .

支气管哮喘从本质上讲是一种气道慢性炎症性疾病，eos在哮喘患者气道内的浸润是哮喘的重要特征，也作为哮喘的标志物。

Background Asthma is one kind of chronic airway inflammation characterized by eosinophil recruitment and mast cell response .

白介素8（Interleukin8，IL-8）是慢性炎症反应中常见的趋化因子，在调节局部炎症反应中起重要作用。

Interleukin-8 is a common chemokines in chronic inflammatory response , play an important role in regulating the local inflammatory response .

肝细胞癌（Hepatocellularcarcinoma，HCC）是最常见的一种肝癌。乙肝、丙肝病毒感染或肝硬化引发的慢性炎症最终往往导致肝癌的发生。

Hepatocellular carcinoma ( HCC ) is one of the most common liver tumor , which mostly caused by chronic inflammation after HBV , HCV infection or cirrhosis .

研究背景近年来越来越多的证据显示，糖尿病视网膜病变（Diabeticretinopathy，DRP）早期是一种低度慢性炎症。

Background More and more evidence show that diabetic retinopathy ( DRP ) is an inflammatory disease at chronic low grade .

方法应用免疫组化ABC法结合显微图像分析，对博莱霉素（BLM）致大鼠肺纤维化的慢性炎症过程中肺组织内ICAM-1的表达进行了动态定量分布研究。

Methods The distribution and the quantity of ICAM-1 expression in rat lungs were determined by immunohistochemical and image analysis .

结论支气管扩张症肺组织高水平CT表达可能与其慢性炎症改变有关，其局部CT表达增高可能系机体对支气管扩张病变的一种局部性代偿或调节机制。

Conclusion The high levels of CT expression in bronchiectasis are closely related to the change of chronic inflammation in bronchiectasis , which may be a kind of local compensatory or regulative mechanism for bronchiectasis .

已经证明，COX-2与急慢性炎症、关节炎、发热、疼痛、肿瘤以及Alzheimer症等疾病的发生、发展密切相关。

It is proved that COX-2 is closely related to inflammation , arthritis , febrile response , hyperalgesia , tumor and alzheimer 's diseases .

主要用于COPD急性发作期及其它气道急慢性炎症患者痰液粘稠时；

It is mainly used in COPD acute infection period and other patients with respiratory tract acute & chronic inflammation when sputum is stiff . The No.

研究显示，AS是一种慢性炎症过程，细胞间黏附分子-1（Intercellularadhesionmolecule-1，ICAM-1）与此过程关系密切。

Research display that AS is an especially kind chronic inflammation process , and intercellular adhesion molecule-1 ( ICAM-1 ) associates with this process closely .

结论推测慢性炎症下MCP-1激活单核巨噬细胞系统，诱导VEGF表达，与膀胱癌的发生密切相关。

Conclusion That MCP-1 activate mononuclear phagocytic system under chronic inflammation , which induce VEGF expression have a close correlation with the carcinogenesis of bladder .

在啮齿动物的研究中，提示iNOS活动在实验性自身免疫性或慢性炎症过程及其他一些疾病中可能起了有害作用。

In rodents experiments suggesting that iNOS activity play a harmful role in experimental autoimmune or chronic inflammatory processes , and several other diseases .

眼球穿通伤后慢性炎症发病机制的免疫学探讨&Ⅱ血清免疫球蛋白和C3测定及意义

The Immunological Study on the Mechanism of Chronic Intraocular Inflammation Following Penetrating Eye Injury-The Measurement of Seral IgS , C3 and its Significance

用RT-PCR和免疫组织化学方法观察电针对慢性炎症痛大鼠脊髓COX-2mRNA和蛋白表达的影响。

And for determining the expression of spinal COX-2 mRNA and COX-2 protein in the dorsal horns of the lumbar spinal cord , immunohistochemical and RT-PCR techniques were carried out .

结果A组BALF细胞总数、以嗜酸性粒细胞为主的炎性细胞数量及蛋白浓度均低于C组（P<001），其肺组织气道慢性炎症表现亦较C组减轻。

Results The numbers of total cells , eosinophil , lymphocyte and neutrophils , the concentration of protein in BALF from group A were significantly lower than those from group C ( P < 0.01 ) .