左旋西替利嗪

以苯甲酰氯为原料，经酰化，还原，环合等反应合成左旋西替利嗪盐酸盐，反应总收率为8.05%。

Levocetirizine Dihydrochloride was prepared from benzoyl chloride by acidylation , hydrogenation , cyclization with an overall yield of 8.05 % .

结论：左旋西替利嗪在正常人体内的分布呈二室开放模型，主要药动学参数与国外文献报道一致，所建立的方法简便、快速、准确，适用于药动学研究。

The main pharmacokinetic parameters were similar to those reported abroad . The method is accurate , simple and sensitive and suitable for the study of pharmacokinetics .

方法：按随机数字表法将60例患者分为两组，针刺拔罐结合刺络放血30例为治疗组，口服迪皿（左旋西替利嗪）30例为对照组。

Method : All of the 60 patients were divided into two groups randomly . The 30 cases were the treatment group , and other 30 cases were the control group of oral using of Dimin ( Levocetirizine Hydrochloride Tablet ) .