多重耐药

突变型p53与胃癌多重耐药基因表达的相关性研究

Study on relationship between mutant p53 and multidrug resistance gene 1 in gastric cancer

K562细胞多重耐药机制的实验研究

Study on the mechanism of multidrug resistance in K562 cell

多重耐药伤寒沙门氏菌流行菌株接合性R质粒的特征

Characterization of conjugative R Plasmids from multiple drugresistant strains of Salmonella typhi in an epidemic

复合PCR鉴别葡萄球菌及其多重耐药基因

Identification of Staphylococcus aureus and detection of its multiple-resistant genes by multiplex PCR

目的：探讨多黏菌素B对多重耐药铜绿假单胞菌（PAE）的体外作用。

Objective : To explore the effect of polymyxin B against multi-resistant pseudomonas aeruginosa ( PAE ) .

年龄、APACHEⅡ评分和多重耐药是死亡的主要危险因素。

And the age , APACHE ⅱ score and multidrug resistance were main risk factors of death .

Ⅰ类整合子与产ESBLs肺炎克雷伯菌多重耐药关系的研究

Identification of class ⅰ integrons and multidrug resistance in ESBLs-producing Klebsiella pneumonia

M1型多重耐药现象依然严重。

The status of M1 type with multi-drug resistance was still severe .

多重耐药鲍曼不动杆菌AdeABC外排机制研究内外部EGR控制二甲醚发动机的燃烧与排放

Combustion and Emission Control in DME Engine Using Internal-External Exhaust Gas Recirculation

对于多重耐药菌株，采用多重PCR技术对其携带的3类整合子进行检测，同时对整合子阳性菌株进行基因盒分析。

Multiplex PCR was used to detect 3 different classes of integron in multi-resistant strains , and PCR-sequencing method was used to analysis gene cassettes .

阴沟肠杆菌AmpC酶阳性菌株中整合子参与的多重耐药

Integron involved drug-resistant mechanism in AmpC enzyme positive Enterobacter cloacae clinical strains

MRSA患者多数伴有复合感染，且对抗生素表现为高度耐药和多重耐药。

The MRSA patients tended to complex infection .

多重耐药阴沟肠杆菌临床分离株ESBLs基因型别和分子流行病学分析

Multidrug-resistant Clinical Enterobacter cloacae Isolates : Analysis of Their ESBLs Gene Types and Molecular Epidemiology

目的：结合临床化疗效果探讨白血病多重耐药（mdr）的诊断方法。

Objective : To study diagnosing method of multidrug resistance with leukemia combining clinical chemotherapy effect .

结论MRSA是多重耐药细菌。

CONCLUSIONS MRSA is a multi-resistant pathogen .

ICU医院感染多重耐药菌类型、耐药性及感染相关因素研究Necroptosis克服肿瘤多药耐药性

Analysis of bacterial type , drug resistance and infection related factor of multi-drug resistant strains of nosocomial infection in ICU patients

Logistic回归分析表明只有院内感染、抗生素应用时间与发生多重耐药菌感染有关。

By multivariable logistic regression analysis , We found only nosocomial infection and duration of antibiotic treatment before infection were the risk factors for antibiotic multi-resistance bacterial infection .

6株qnr基因阳性菌株均为产超广谱β内酰胺酶（ESBLs）且多重耐药菌株。

Strains with qnr gene were ESBLs producing and multidrug-resistance strains .

ESBLs通常为质粒介导，同一质粒可同时携带多个耐药基因，引起多重耐药。

ESBLs are a kind of plasmid-mediated enzymes , these plasmids often carry two or more resistant genes .

结论医院获得性MRSA是多重耐药菌，ICU的MRSA菌株主要基因型为A、B型。

Conclusions Hospital acquired MRSA is multi-resistant to antibiotics . Genotypes A and B are prevalent MRSA in ICU .

金葡菌多重耐药基因norA的原核表达及其抗体制备

Prokaryotic expression of the multi-drug resistant norA gene of Staphylococcus aureus and its antibody preparation

MRSA临床分离株大多是多重耐药，仅对糖肽类抗生素如万古霉素敏感。

MRSA clinical isolates are typically multidrug resistant and could only be treated with glycopeptides such as vancomycin .

结论产ESBLs鲍曼不动杆菌常为多重耐药菌，耐药率与产ESBLs密切相关；

Conclusion ESBLs producing strains usually were muti-drug resistance and the drug resistant rate was closely associated with ESBLs .

然而随着抗生素的广泛使用，临床频繁出现耐药志贺菌属菌株，而且呈现为多重耐药（multi-drugresistance，MDR）。

However , with the wide use of antibiotics , resistant isolates of Shigella spp. , especially multiresistant isolates with multi-drug resistance ( MDR ), occurred .

多重耐药鲍曼不动杆菌临床株与RND型和MATE型外排泵的研究

RND-Type and MATE-Type Efflux Pumps Involved in Multidrug Resistance in Clinical Isolates of Acinetobacter Baumannii

大肠杆菌多重耐药基因AcrA、AcrB内标准DNA的构建

Construction of Internal Standard DNA of Multi-Drug Resistance Gene AcrA and AcrB of E. coli

MRSA呈现出的异质性及多重耐药的特点[1]为治疗提出了挑战。

The heterogeneity and multiple drug resistance of MRSA [ 1 ] are a kind of challenge to treatment .

结论ICU为耐亚胺培南铜绿假单胞菌感染高发病区，也是多重耐药菌株感染较多的病区，应重点监控。

Conclusion ICU is a high risk area of infection with imipenem-resistant Pseudomonas aeruginosa and other multiply-resistant bacteria , which should be given strengthened surveillance .

许多研究表明多重耐药（MDR）是肿瘤细胞耐药的主要形式，同时也是导致化疗失败的主要原因。

Multidrug resistance ( MDR ) is a main phenomenon observed within tumor cells which is a major obstacle to failure of chemotherapy .

枯草杆菌多重耐药基因bmr的克隆及原核表达

Cloning and Prokaryotic Expression of Multidrug Resistance bmr Gene in Bacillus subtilis