去甲万古霉素

盐酸去甲万古霉素纯度控制方法的改进

Improvement of RP-HPLC in the Purity Control of Norvancomycin Hydrochloride

眼内注射去甲万古霉素治疗细菌性眼内炎临床观察

Intraocular injection of norvancomycin hydrochloride for treating bacterial endophthalmitis

建立快捷、实用的去甲万古霉素治疗药物监测（TDM）方法。

And to establish a rapid method for therapeutic drug monitoring ( TDM ) of norvancomycin .

去甲万古霉素和（或）阿米卡星可作为治疗CRS的首选用药。

Vancomycin and ( or ) amikacin may be first chosen to treat CRS .

万古霉素和去甲万古霉素对MRSA无1例耐药。

MRSA was very sensitive to both vancomycin and norvancomycin with no report of antibiotic resistance to them .

结果：抗菌药对肠球菌的MIC值以去甲万古霉素最低、红霉素最高；

Results : In the MIC of the antimicrobic agents against Enterecoccus vancomycin was the lowest and erythromycin was the highest ;

结论：眼内注射国产盐酸去甲万古霉素08～1mg是治疗细菌性眼内炎有效而安全可靠的方法。

Conclusion : Intraocular injection of norvancomycin HCl is safe and effective treatment for bacterial endophthalmitis .

结论：去甲万古霉素15mg·kg－1静脉滴注后，能够维持有效药物浓度，用药间隔应为8～12h。该药物用于新生儿耐药葡萄球菌感染安全、有效。

CONCLUSION : Demethylvancomycin could maintain the effective concentration in neonates at the dosage of 15mg · kg - 1 and the dosage interval should be 8 ~ 12h .

复合移植组患者中应用去甲万古霉素400mg和庆大霉素16万单位渗入同种异体骨和自体骨中。

The allochthonous bone and autoplastic bone were immersed into 160 thousands of gentamicin and 400 mg of norvancomycin used for patients in the compound transplantation group .

实验组分为（1）局部用药组：HAC中加入去甲万古霉素，植入家兔胫骨上端；

Experimental samples were divided to three groups : ( 1 ) Part drug group : the hydroxyapatite bone cement / norvancomyicn ( HAC / NVCM ) compound was implanted to tibiae of rabbit .

建立了高效液相色谱（HPLC）法和胶束电动毛细管色谱（MECC）法测定盐酸去甲万古霉素中去甲万古霉素的含量。

An high performance liquid chromatography ( HPLC ) method and a micellar electrokinetic capillary chromatography ( MECC ) method for determination of the content of norvancomycin ( NV ), the primary component in NV hydrochloride , were established .

目的探讨去甲万古霉素载药涤纶血管材料（NV-DP）的制备，并对其形态特征、载药量、体外释药性能和有机溶剂残留量进行观察。

Objective To explore the preparation of norvancomycin-bonded Dacron prosthesis ( NV-DP ) and evaluate its morphology , drug loading , in vitro release and organic solvent residue .

方法：采用前瞻性开放性的方法，用国产去甲万古霉素治疗耐甲氧西林葡萄球菌肺部感染病人共34例，每日总量1.2g，治疗平均10.2d，观察其症状体征变化及细菌清除情况。

Method : 34 patients with the infection of Staphylococcus strains of methicillin resistant were treated with norvancomycin ( 0.4g tid , average 10.2d ), and clinical efficacy of the drug and elimination rate of bacteria was evaluated .

结论去甲万古霉素是具有成本效果的。

CONCLUSION Demethylvancomycin appeared to be cos effective in this study .

去甲万古霉素致白血病患者急性肾损害

Acute renal injury caused by norvancomycin in a patient with leukemia

去甲万古霉素-肝素冲洗预防中心静脉导管相关感染

Prophylactic use of norvancomycin-heparin flushing for central venous catheter related infection

盐酸去甲万古霉素及其注射剂效价的浊度法研究

Content determination of Norvancomycin Hydrochloride and it for injection by turbidimetric method

去甲万古霉素治疗革兰阳性球菌感染的安全性评价

Clinical safety evaluation of norvacomycin in patients with gram - positive bacterial infections

去甲万古霉素键合毛细管电色谱硅胶整体柱的制备及应用

Preparation of Norvancomycin-Bonded Chiral Silica Monolithic Column for Capillary Electrochromatography and Its Applications

最有效的抗生素是去甲万古霉素。

The most sensitive antibiotic for hypospadias is demethovancomycin .

盐酸去甲万古霉素的高效液相色谱和胶束电动毛细管色谱分析

Analysis of norvancomycin by high performance liquid chromatography and micellar electrokinetic capillary chromatography

去甲万古霉素改善化疗相关性腹泻患者生活质量的作用

Relationship of norvancomycin treating patients with chemotherapy-induced diarrhea to improving quality of life

注射用盐酸柔红霉素去甲万古霉素治疗耐甲氧西林葡萄球菌感染的临床调查分析

Clinical analysis of norvancomycin hydrochloride for injection on methicillin resistant staphylococcus aureus infection

去甲万古霉素临床药代动力学及血药浓度监测

Clinical pharmacokinetics and therapeutic drug monitoring of norvancomycin

羟磷灰石骨水泥/去甲万古霉素体外缓释试验

Drug releasing test in vitro of hydroxyapatite cement / norvancomycin as drug delivery system

结论去甲万古霉素对耐甲氧西林葡萄球菌泌尿系统感染有着较好的疗效。

Conclusion Norvancomycin is very efficient on the treatment of severe MRSA urinary system infection .

目的：观察盐酸去甲万古霉素的不良反应，以便临床应用。

Objective : To observe the side effect of d eme thyl-vancomycin for clinical application .

去甲万古霉素键合手性固定相拆分β-受体阻滞剂类药物及其结构类似物的研究

Chiral Separation of β - Receptor Blockers and Analogs on Novel Norvancomycin-Bonded Chiral Stationary Phase

进口万古霉素与国产去甲万古霉素治疗耐甲氧西林金葡球菌下呼吸道感染的对比研究

Comparative effect of vancomycin and norvancomycin on lower respiratory tract infections caused by methicillin-resistant Staphylococcus aureus

去甲万古霉素的低药物获得成本是其总成本明显低于万古霉素的主要因素。

Lower drug acquisition cost of demethylvancomycin was the major reason for its better cost effectiveness .