外消旋体

它们都是手性分子，属于外消旋体。

They are all chiral molecules and belong in the racemate .

外消旋体是不旋光的。

The racemate is optically inactive .

测定它们对20株临床分离和标准革兰阴性菌和标准革兰阳性菌的最低抑菌浓度。结果表明，5a和5b的体外抗菌活性与外消旋体5c基本相当。

The in vitro antibacterial activities of 5a and 5b against 20 Gram-negative and Gram-positive bacteria were comparable to that of racemic compound 5c .

综述了前列腺素的关键手性中间体&Coreylactone的制备方法，重点阐述了Coreylactone的外消旋体拆分法，不对称合成法及手性源原料法的最新研究进展。

The paper surveys the preparation of chiral Corey lactone , a key intermediate in prostaglandins synthesis , including optical resolution , asymmetric synthesis and chiral pool .

综述了催化氧化偶联2-萘酚合成外消旋体1,1′-联二萘酚（BINOL）的方法。

Synthesis of racemic 1,1 ′ - bi-2,2 ′ - naphthol ( BINOL ) by catalytic oxidative coupling of 2-naphthol was reviewed .

以乙醇水为流动相，用纤维素三（苯甲酰酯）（CTB）作为手性固定相对外消旋体托品酸进行了高效液相色谱手性分离。

Reverse phase chromatography was employed for chiral separation of tropine acid enantiomers on the cellulose tribenzoate ( CTB ) chiral stationary phases coated on a small particle spherical silica support in an eluant system consisting of a mixture of alcohol and water .

含氨基酸的手性化合物外消旋体的制取方法

Method of Preparation in Chiral Compound 's Racemate of Amino Acids

外消旋体拆分是获得单一手性化合物的重要途径。

Raceme separation is the main rout for preparation of pure enantiomers .

结果：合成外消旋体蒜氨酸。

Results : The racemic body alliin is obtained .

一种新型气相色谱手性固定相的制备及其对苄腈外消旋体的拆分

Preparation of a New Chiral GC Stationary Phase and Resolution of Benzyl Cyanide Enantiomers

2-（9-蒽基）-2-羟基乙酸及其衍生物的外消旋体拆分

Resolution of racemic 2 - ( 9-anthranyl ) - 2-hydroxyacetic acid and its derivations

手性流动相添加法拆分酮康唑外消旋体

Separation of ketoconazole enantiomers using high performance liquid chromatography with chiral mobile phase additives

酶催化外消旋体的动态动力学拆分反应研究进展

Dynamic Kinetic Resolution of Racemes Catalyzed by Enzyme

在正相色谱条件下，对15种外消旋体化合物进行拆分，其中11种手性化合物得到了好的分离。

Among the 15 racemates , 11 chiral compounds could be separated on the column .

利用外消旋体进行化学-酶催化动态动力学拆分是制备单一手性化合物的有效手段之一。

The methods of kinetic resolution , dynamic kinetic resolution and enantioconvergence resolution were compared with each other .

以有机碱为催化剂，通过三唑三甲基丙酮与2，4-二氯苯甲醛的反应，合成了具有生物活性的外消旋体化合物烯唑醇。

By using alkalamides as the catalyst , diniconazole has been synthesized by the reaction of triazolyl-trimethylacetone and2,4-dichlorobenzaldehyde .

萃取拆分技术适用性强、于连续拆分有望成为外消旋体拆分分离操作的先进技术。

It is hopeful that the extraction separation method will become the advanced technique for the racemates separation .

介绍一个绿色化的外消旋体化合物拆分与光活性表征的微型综合化学实验。

A new comprehensive chemistry experiment study on the optical resolution and the characterization was introduced as microscale laboratory .

还可以少走弯路，加快研发进度。此外，开展手性研究对正确评价外消旋体药物，指导临床合理用药也具有重要的意义。

Furthermore , the research on the chiral drugs has significance of evaluating the racemate drug in clinical application .

脂肪酶催化的外消旋体动力学拆分是不对称催化领域中极具吸引力且发展非常迅速的重要技术。

Lipase-catalyzed kinetic resolution of racemates is considered to be one of the most fascinating topics in asymmetric catalysis .

间歇式液相本体法聚丙烯闪蒸操作分析厚体液膜拆分克伦特罗外消旋体及其动力学研究

Operation Optimization of Bulk Liquid Phase PP Plant Resolution of Racemic Clenbuterol by Bulk Liquid Membrane and Study on Its Kinetics

苯甘氨酸外消旋体的红外光谱及其对映异构体色谱拆分三点作用原理关系间的探讨

Discussion of the application of three-point interaction principle to the phenylglycine racemic compound in IR spectrometry and its enantiomers separation in HPLC

通过微生物酶催化不对称合成反应或拆分外消旋体合成医药手性中间体具有独特的优势。

Recent progress in transformation with microbial enzyme including asymmetric catalysis synthesis and racemic reduction techniques to produce chiral drug were reviewed .

本文讨论了路易斯酸及路易斯碱催化体系在外消旋体（动态）动力学拆分反应中应用的最新进展。

Recent progress in the applications of non-enzymatic system about Lewis acid and base to ( dynamic ) kinetic resolution reactions of racemes is reviewed .

然而，催化剂met-Ⅱ在聚合过程中遵循双活性中心模型，可推测在催化剂met-Ⅱ体系中，有较为稳定的类外消旋体构象的存在。

However , met-II obeys the concurrent two-sites model during polymerization , which can be attributed to the existence of " racemic-like " conformer in its system .

本文综述了外消旋体的拆分方法，包括机械拆分法、化学拆分法、生物化学拆分法、色谱拆分法、萃取拆分法、膜拆分法等六大类方法。

This article reviews resolution methods of raceme which includes six categories , such as mechanical , chemical , biochemical , chromato-graphic , extractive and membranous methods .

综述了近年来含氨基酸的手性化合物外消旋体的制取方法，并展望了其研究发展的前景。

Recent research progresses of method of preparation in chiral compound 's racemate of amino acids were reviewed in this paper , the possible development future of it was predicted .

手性氨基醇在不对称合成领域中是一类重要的手性源，同时，手性氨基醇在药物合成、外消旋体拆分等领域也具有广泛的用途。

Chiral aminoalcohol is an important kind of chiral substance in the asymmetric synthesis , meanwhile , it is widely used in the field of medicine synthesis and the resolution of raceme .

目的研究氧氟沙星对映体在手性环境中的萃取分配行为，为外消旋体膜萃取拆分提供理论和设计依据。

AIM Distribution behavior of ofloxacin enantiomers was examined in the aqueous and organic solvent of a two-phase system containing a chiral selector , and the theory was provided for separation of racemic mixtures by solvent extraction .

分别往正己烷/乙醇或正己烷/异丙醇中添加四氢呋喃和二氯甲烷，系统地考察了四氢呋喃和二氯甲烷的含量对安息香外消旋体拆分的影响。

The primary composition of mobile phase was ( hexane / ethanol ) or hexane / isopropanol . Then the tetrahydrofuran ( THF ) or dichloromethane was added into such mobile phase and the effects of content of THF and dichloromethane on the separation were investigated .