囊膜病毒

病毒囊膜与宿主细胞膜的融合是囊膜病毒入侵宿主细胞的关键步骤。

Membrane fusion between the virus envelope and host cells is the key step of the enveloped virus to enter into the host cells .

腮腺炎病毒（MuV）同其他囊膜病毒相似，在融合蛋白（F）中具有两个七肽重复序列结构域（HR）。

Like other enveloped viruses , Mumps virus ( MuV ) fusion protein ( F ) may possess two heptad repeat domains ( HR ) .

但目前并不清楚MuV是否有类似于其他囊膜病毒的侵染机制。

However , it is unknown whether the MuV has a membrane fusion mechanism similar to that of the other enveloped viruses in the course of host infection .

囊膜病毒膜融合的分子机制

The Molecular Mechanism of Enveloped Virus-cell Membrane Fusion

这是一株无囊膜的RNA病毒。

This is a new RNA virus without envelope .

ND的病原为新城疫病毒（NDV），属副黏病毒科腮腺炎病毒属的成员，是一种具有囊膜的RNA病毒，严重地危害着养鸡业的发展。

The pathogen of ND is Newcastle disease , a member of the paramyxovirus Division mumps virus , and is an enveloped RNA virus , seriously harm the development of the chicken industry .

E2囊膜糖蛋白为病毒最主要的保护性抗原，可以诱导机体产生保护性抗体。

E2 glycoprotein of CSFV , which is the protecting antigen and induces the neutralizing antibody during the infection of CSFV , is 1119 base pairs in length and encodes 373 amino acid residues .

猪圆环病毒属圆环病毒科，是一种小型、无囊膜，单链DNA病毒。

Porcine circovirus ( PCV ), a member of the Circoviridae family , is a small , non-enveloped , spherical single-stranded DNA virus .

鸭肠炎病毒属于α-疱疹病毒科，gB和gC是其两种重要的囊膜糖蛋白，在病毒感染宿主细胞过程中的受体识别和吸附过程中起重要作用。

DEV belongs to alpha herpesvirus families . Glycoprotein B and C plays an important role in receptor recognition and adsorption to host cells during DEV infection .

科Megapodagriidae：藏（？）猪轮状病毒（PRV）属于呼肠孤病毒科轮状病毒属，为无囊膜、双股RNA病毒。

Porcine Rotavirus ( PRV ) is a member of Rotavirus of Reoviridae family , a kind of no capsule membrane , double helix RNA virus .

囊膜蛋白为疱疹病毒的主要保护性抗原，它在介导病毒进入细胞，以及病毒的成熟与释放中均起重要的作用。

Envelope protein is the major protective antigen of herpesvirus .

假型病毒与提供囊膜蛋白的真病毒一样，对宿主细胞有同样的侵染性。

Pseudotyped virus has true virus envelope protein , so it has the same infection to host cells .

此病毒的形态发生起始于细胞核，并可分为4个阶段：病毒基质的形成、囊膜的形成、病毒的装配和完整的病毒粒子的形成。

Beginning in the nuclei the viral morphogenesis process was composed of four stages : formation of viral stroma , formation of membrane , assembly of the virus and formation of complete virons .