喹唑啉

抗癌性吲哚喹唑啉衍生物3D-QSAR研究及其分子设计

3D-QSAR Study of a Series of Indolo [ 1,2-b ] quinazoline Derivatives with Antitumor Activity and their Molecular Design

具有抗肿瘤作用的2,4-二氨基-6-取代氨基喹唑啉类化合物

Antitumor effects of 2,4-diamino-6 - ( n-substituted amino ) quinazoline derivatives

2-取代-4（3H）-喹唑啉酮类化合物合成研究进展

Progress on Synthesis of 2-Substituted-4 ( 3H ) - quinazolinone Derivatives

微波辐射合成7-硝基-4（3H）-喹唑啉酮

Synthesis of 7-nitro-4 ( 3H ) - quinazolinone under microwave irradiation

2-取代的6-溴甲基-4（3H）-喹唑啉酮的合成

Syntheses of 2-Substituted 6-Bromomethyl 4 ( 3H ) - Quinazolinones

抗球虫药常山酮中间体7-溴-6-氯-4（3H）-喹唑啉酮的合成

Synthesis of Anticoccidial Drug Halofuginone Intermediate of 7-Bromo-6-chloro-4 ( 3H ) - quinazolinone

禽兔抗球虫药常山酮的合成研究&Ⅰ.中间体6-氯-7-溴-4（3H）喹唑啉酮的制备

Study on the Synthesis of Halofuginone ⅰ . Preparation of Intermediate 7-bromo-6-chloro-4 ( 3H ) - quinazolinone

吡唑啉及其衍生物的合成与抗菌活性研究2,3-二取代-4（3H）-喹唑啉酮衍生物的合成研究进展

Synthesis and Antibacterial Activity of Pyrazoline and Its Derivatives Progress on Synthesis of 2,3-Disubstituted-4 ( 3H ) - quinazolinone Derivatives

合成五种喹唑啉类EGFR-TK抑制剂的新方法

A new approach to synthesizing five quinazolines as EGFR inhibitors

研究以硝基苯为起始原料，经过溴化、还原、缩合、环化等七步反应，合成了7-溴-6-氯-4（3H）-喹唑啉酮，总收率为60%。

7-bromo-6-chloro-4 ( 3H ) - quinazolinone is an important intermediate of anticoccidial drug halofuginone , which was prepared from nitrobenzene by bromination , reduction , condensation , cyclization and so on . The overall yield of the seven-step is 60 % .

2,4-二氨基-6-[N-甲基（对氯苄基）氨基]喹唑啉盐酸盐（SIPI-759）属非经典叶酸拮抗剂。

2,4-Diamino-6 - [ N-methyl ( 4-chlorobenzyl ) amino ] quinazoline ( SIPI-759 ) is a non-classic antagonist of folic acid .

用HF/6-31G（d）方法优化了1,2,3,4-四氢喹唑啉（THQ）衍生物的结构，并进行了频率分析以保证优化的结构是稳定的。

The structures of the derivatives of 1,2,3,4-tetrahydroquiazoline ( THQ ) are optimized at the HF / 6-31G ( d ) level . Vibrational frequency analysis is performed at the same level to ensure that the optimized geometry is stable .

微波辐射下2-氨基苯并[h]喹唑啉衍生物的合成

Synthesis of 2-Amino-benzo [ h ] quinazoline Derivatives under Microwave Irradiation

六取代三环喹唑啉分子可以作为液晶半导体材料。

Hexa-substituted tricycloquinazoline molecule has been regarded as liquid crystalline semiconductors .

喹唑啉分子印迹聚合物微球的吸附特性

Study of Binding Characteristics of Quinazoline Molecularly Imprinted Polymeric Microspheres

α-硫羰基膦酸衍生化喹唑啉酮含磷类似物的研究

Studies of α - Thiocarbonyl Phosphonic Acid Derivative Quinazolone Analogues Containing Phosphorus

喹唑啉稠合螺杂环化合物的合成及晶体结构

Synthesis and Crystal Structure of the Fused Quinazoline Spiro-heterocyclic Compounds

苯腈类母体化合物缓蚀性能的量子化学计算喹唑啉酮类化合物的合成

Quantum chemistry calculation on inhibition behavior of parent compounds of benzene nitriles

2,4-二氨基-6-取代氨基磺酰喹唑啉类化合物抗鼠疟作用的研究

Antimalarial activity of some 2,4-di amino - 6-substituted amino sulfonyl quinazoline derivatives

新型喹唑啉类酪氨酸激酶化学抑制剂的设计与合成

Design and Synthesis of Novel Quinazoline Derivatives as Tyrosine Kinase Chemical Inhibitors

二环己基二甲氧基硅烷的合成抗肿瘤喹唑啉衍生物的定量构效关系

Quantitative Structure-activity Relationship of Quinazoline Derivatives with Antitumor Activity

喹唑啉类杂环化合物的化学&Ⅲ.N~1，N~3-二氧化-4-羟基喹唑啉的分子重排反应

Chemistry of the quinazoline series ⅲ . molecular rearrangement of 4-hydroxy quinazoline di-N-oxide

色胺酮属吲哚喹唑啉类生物碱。

Tryptanthrin is a kind of indole quinazoline alkaloid .

6-氟-4-（N-芳基）胺基喹唑啉类化合物的微波合成及生物活性研究

Synthesis and Bioactivity of 6-Fluoro-4 - ( N-aryl ) aminoquinazoline Compounds under Microwave Irradiation

该研究为喹唑啉类抗肿瘤药物的开发提供了新的思路。

This study provides new insights for the development of quinazolines as anti-cancer agents .

尤其是在抗肿瘤药物研究领域，喹唑啉类化合物发挥了重要作用。

Quinazolines have particularly played important roles in the discovery and development of anticancer drugs .

方法：以邻甲苯胺为原料设计并合成喹唑啉类化合物；

Methods : 2 methyl aniline as the material , quinazolines were designed and synthesized ;

喹唑啉类衍生物定量结构保留关系的研究

On quantitative structure-retention relationship for quinazoline derivatives

2,4-二氨基-6-（N-甲基-取代苄氨基）喹唑啉类化合物的合成和抗疟以及抗肿瘤活性

Synthesis and antimalarial as well as antitumor activities of 2,4-diamino-6 - ( n-methyl-substituted benzylamino ) quinazolines

研究了10种2,4-二氨基-6-取代磺酰胺喹唑啉类药物的电子电离及场解吸质谱。

The electron impact and field desorption mass spectra of 10 2,4-diamino-6-substituted quinazoline sulfonamides were investigated .