双硫仑

综述了双硫仑及其制剂的研究进展，包括其合成和理化性质、制剂研究、分析方法、药代动力学、作用机制、临床应用和新用途等。

The synthesis , physico-chemical properties , research on dosage forms , analysis , pharmacokinetics , mechanisms , clinical uses and new development in uses of disulfiram were reviewed .

双硫仑样反应出现于使用头孢菌素的过程中及疗程结束后72h内。

Disulfiram-like reaction appears when cephalosporin was being used or within 72 hours after cephalosporin had been used .

目的测定双硫仑羟丙基β环糊精（DSFβCDHP）的包合常数；研究包合物形成的热力学性质。

Objective To study the thermodynamic properties of disulfiram-hydroxypropyl - β - cyclodextrin ( DSF - β - CD_ ( HP )) inclusion complexes and determine the equilibrium constants of the inclusion complex .

头孢哌酮钠治疗期间饮酒致双硫仑样反应2例

Two cases of drinking induced disulfiram like reaction during cefoperazone sodium treatment

60例头孢菌素致双硫仑样反应临床分析

60 cases of Cephalosporin-induced disulfiram-like reaction analysis of the clinical

美国仿制药管理的法制历程及其对我国的启示戒酒药双硫仑

Legal Course of Generic Drug Management in USA and Its Enlightenment to China

急诊救治双硫仑样反应92例临床分析

Emergency salvage of 92 patients who suffered disulfiram-like reactions

头孢曲松钠静滴致双硫仑样反应

Disulfiram-like reactions during intravenous infusion of ceftriaxone sodium

甲硝唑引起双硫仑样反应

Disulfiram-like reaction induced by metronidazole

导致双硫仑样反应的药物见于头孢唑啉、头孢哌酮、头孢哌酮加舒巴坦、拉氧头孢等。

Disulfiram-like reaction can be caused by cephazolin , cefoperazone , cefoperazone and sulbactam , latamoxef and so on .

头孢哌酮舒巴坦用药过程中饮酒致双硫仑样反应1例头孢哌酮钠/舒巴坦钠致过敏性休克

Case of similar reaction to the medicine for drinking alcohol at using the cefoperazone sodium and sulbactam sodium Anaphylactic shock under cefoperazone / sulbactam therapy

本文就头孢类药物的主要不良反应如过敏性休克、溶血反应、双硫仑样反应、神经毒性和出血反应机制做出总结和归纳。

This paper will sum up the mechanisms of cephalosporin 's major adverse reactions such as anaphylactic shock , hemolytic reaction , disaffirm-like reaction , neurotoxicity and bleeding .