原弹性蛋白

大鼠大脑中动脉原弹性蛋白mRNA表达的增龄变化

Aging changes of tropoelastin mRNA expression in middle cerebral artery in rats

目的：检测各年龄组大鼠大脑中动脉原弹性蛋白mRNA表达的变化。

Objective : To study the changes of tropoelastin mRNA expression in middle cerebral artery ( MCA ) in rats of different ages .

肺动脉高压及高肺血流对肺小动脉壁弹性蛋白离解与原弹性蛋白mRNA表达的影响

Effects of the pulmonary hypertension and high lung blood flow on elastolysis and the expression and distribution of tropoelastin mRNA in pulmonary arteriole walls

结论：左向右分流型先心病肺高压时出现原弹性蛋白mRNA再表达且蛋白积聚位置异常，肺血管壁高张力（高压力）是弹性蛋白合成增加的主要促成因素。

It is concluded that hypertension of pulmonary arteriole , that is main factor to promote the increase of elastin synthesis , can lead to both of re-expression of tropoelastin mRNA and accumulation of elastin in abnormal sites .

研究脉动脉压力对肺小动脉壁原弹性蛋白表达与分布的影响以帮助阐明先天性心脏病（先心病）肺动脉高压（肺高压）肺血管重建的发病机制。

To explore the pathogenesis of pulmonary vascular remodeling in the existence of pulmonary hypertension ( PAP ) complicated by congenital heart diseases ( CHD ) in children .

结果显示：（1）直径为0.1～0.2μm原纤维是弹性蛋白基本结构单位。

The results revealed that : ( 1 ) The basic structural unit of the elastin was fibril with a diameter of 0.1 ~ 0.2 μ m.