分子标志物

  • 网络biomarker;molecular marker
分子标志物分子标志物
  1. 结论Livin表达与TCC的发生有关,可作为TCC的分子标志物,可能成为TCC诱导凋亡治疗的新靶点。

    Conclusions It is indicated that Livin may play a significant role in the TCC development . Livin might be a biomarker for the detection of TCC and served as a new target for apoptosis-inducing therapy of TCC .

  2. 氮芥所致DNA损伤分子标志物探讨

    Study on molecular biomarker of DNA lesion induced by nitrogen mustard

  3. 正常妊娠妇女血中活化的蛋白C抵抗、狼疮样抗凝物质与血栓前状态分子标志物测定

    Measurement of activated protein C resistance , lupus-like anticoagulant and prethrombotic markers in normal gestation

  4. 活化血小板分子标志物:P-选择素、糖盏蛋白和糖蛋白V的研究进展

    The Study Progress of P-selectin , Glycocalicin and Glycoprotein V of Activated Platelet Molecular Markers

  5. 纤维蛋白原、超敏C反应蛋白、转化生长因子β1等分子标志物增高可能是搭桥术后吻合口内膜增生的危险因素。

    Higher levels of FIB , HsCRP , TGF - β 1 may be the major high risk factors resulting in neointima hyperplasia of anastomotic restenosis .

  6. 天津表层土壤PAHs分子标志物参数的空间特征

    Spatial characteristics of PAHs molecular marker indices in surface soil of Tianjin

  7. 结论TM作为新的血管内皮损伤的分子标志物对临床有重要价值。

    Conclusions TM can be used as a new molecular marker to detect the injury of endothelial cells .

  8. 血液系分子标志物检测在DIC前期诊断中的应用

    Application of monomolecular label detecton of blood in the diagnosis of DIC protophase

  9. FPA与D-dimer二种分子标志物检测对糖尿病肾病早期诊断的意义研究

    The early diagnosis meaning study of FPA and D-dimer examination of DN

  10. 通过更加深入的大样本和长期随访研究将有可能发现肝癌早期预警的微RNA分子标志物。

    It is possible to find the miRNA biomarkers for liver cancer early diagnosis if there are large enough samples and long-term follow-up study .

  11. 结论:血栓分子标志物的检测对DM病人高凝状态的诊断具有很高的临床指导意义。

    Conclusion : The alteration of thrombus molecular markers would reveal a higher sensitivity for diagnosis of high coagulation state in DM patients .

  12. 结论(1)mRNA表达水平在24h内反映出含药与无药的区别,是检测和判定结核分枝杆菌死活的分子标志物。

    Conclusions ( 1 ) The levels of mRNA were shown the differences exposure to drugs with no drug , and nearly parallel with CFU .

  13. WT1异常高表达可能是诊断卵巢癌的分子标志物。

    The overexpression of WT1 might be the molecular marker for the epithelial ovarian carcinoma .

  14. 因此,弄清DS的病因,确立DS发病及进展相关的分子标志物,从而找到有效预测和防治侧凸加重的方法对于该病的临床诊治具有重大意义。

    Therefore , It is very important to ascertain the etiology of degenerative scoliosis and establish related molecular markers predicting and controlling the scoliosis .

  15. 直肠癌分子标志物OPN、N-cadherin和MMP-9的蛋白及基因水平研究

    Protein and Genomic Study on Molecular Signature ( OPN , N-cadherin and MMP-9 ) of Rectal Cancer

  16. 结论:通过本实验证实了哮喘时有血小板活化现象,GP可作为血小板活化的分子标志物。

    In conclusion , GP can act as a molecular sign of platelet activation and takes part in attack of asthma through platelet activation .

  17. 止血和凝血分子标志物检测有助于APL病情和疗效观察。

    The detection of hemostatic and coagulative molecular markers can help to observe the state and curative effect of APL .

  18. 目前CARP已经被确定为一个新的心血管疾病的分子标志物,它在胚胎期、新生期和成年哺乳动物心脏中高水平表达。

    Recently , CARP has been identified as a novel marker of cardiovascular disease . There is a high expression of CARP in fetal , neonatal and adult heart .

  19. 结论Gadd基因的表达可以作为判断DNA损伤的比较敏感的分子标志物。

    Conclusion It is possible of expression level of Gadd genes to function as molecular biomarker of DNA damage induced by nitrogen mustard .

  20. 乳腺癌是全世界妇女中发病率最高的恶性肿瘤,在乳腺癌中雌激素受体(ER)常作为一个重要分子标志物用于评估激素依赖性、预测内分泌治疗的效果。

    Objective : Breast cancer is the most common cancer in women . estrogen receptor is usually an important molecule marker to evaluate hormonal dependence and predict the effect of endocrine therapy .

  21. 结论bcl-2、Bax蛋白在肺癌中的表达率较高,bcl-2、Bax可能会成为肺癌的重要分子标志物。

    Conclusion The amount of bcl 2 mRNA and Bax protein increased obviously in lung cancer , bcl 2 and Bax gene can become molecular markers of lung cancer .

  22. 因为并不是所有的肿瘤共有一个特殊的分子标志物,故ATA指南建议使用其他分子标志物。

    He noted that because not all tumors have a particular marker , the ATA guidelines suggest using additional markers .

  23. 方法以纤维蛋白原受体(FIBR)、P选择素(CD62P)作为分子标志物,FCM三色免疫荧光分析CAP。

    Methods The fibrinogen receptor ( FIB R ) and P selectin ( CD62P ) were used for molecular marker of CAP , which were analyzed by flow cytometric 3 color immunofluorescence .

  24. 目的:检测急性早幼粒细胞白血病(APL)患者止血和凝血分子标志物含量变化及其临床意义。

    Objective : To observe the changes of hemostatic and coagulative molecular markers in acute promyelocytic leukemia ( APL ), and explore the clinical significances .

  25. 目的观察急性白血病(AL)止凝血分子标志物的变化以探索其在前DIC(preDIC)诊断中的意义。

    Objective To study the changes of hemostatic molecular markers in acute leukemia ( AL ) patients , for elucidating their significance on diagnosis of pre disseminated intravascular coagulation ( pre DIC ) .

  26. HHcy患者血栓前状态分子标志物的变化

    Changes of Plasma Prethrombotic State Related Molecular Markers Levels in Patients with Hyperhomocysteinemia

  27. 结论常规凝血指标及凝血分子标志物不仅可用于诊断产妇DIC,也是产妇DIC治疗过程中很好的监测指标。

    Conclusions Routine coagulation parameters and coagulation makers are useful indexes not only for the diagnosis of DIC , but also to monitor therapeutic effect of DIC in obstetrics .

  28. Hellyer等比较了mRNA、rRNA和DNA在结核病化疗过程中的变化规律,认为mRNA是结核杆菌活菌诊断的良好分子标志物,优于DNA和rRNA。

    Has studied the changes of mRNA , rRNA and DNA during anti-tuberculosis therapy and drawn a conclusion that mRNA should be a good molecule marker for viable Mycobacterium tuberculosis diagnosis compared with DNA and rRNA .

  29. 结论人类第9号染色体微卫星改变在NSCLC中普遍存在,有可能成为肺癌早期诊断和转移判断的分子标志物。

    Conclusion Microsatellite alteration on chromosome 9p in NSCLC appears to be a common and specific event , and may be a valuable molecular marker for determination of early diagnosis and metastasis of NSCLC .

  30. 结论mdm-2扩增与胃癌的淋巴转移关系较密切,它可能成为监测胃癌淋巴转移的潜在性分子标志物。

    Conclusion The amplification of mdm-2 is well correlated with lymph node metastasis of GC . Mdm-2 gene may be served as a potential genetic marker for monitoring lymph name metastasis of GC .