内毛细胞

谷氨酸是内毛细胞（IHC）和初级听觉传入神经元之间的主要神经介质。

The researches suggest that glutamate is the primary neurotransmitter between IHCs and primary auditory afferent neurons .

而内毛细胞的缺失是发生在注射卡铂后72h。

However , The reduction of the inner hair cells occurred within 72 hours .

耳蜗各回内外毛细胞均呈NOS阳性反应，内毛细胞区较外毛细胞区染色深；

Both internal and external hairy cells of cochlear nucleus show NOS positive reaction . The stain of internal hairy cells were darker than that of the external .

B组：L-乙酰半胱氨酸（NAC）的外毛细胞平均损伤率为65%，内毛细胞平均损伤率为60%。

The mean outer hair cell ( OHC ) loss rate was 65 % in group B , and its mean inner hair cell ( IHC ) loss rate was 60 % .

结果：CGRP阳性反应物分布于螺旋神经元，骨螺旋板神经孔，内毛细胞、外毛细胞与外支持细胞交界区，螺旋韧带血管纹。

Result : CGRP immunoreactivity was located in SGN , nerve fibers at osseous spiral lamina , stria vascularis , IHC , adjacent area of OHC and Deiters ' cells .

谷氨酸（glutamate，Glu）是耳蜗内毛细胞/传入神经突触的神经递质，同时又是一种神经毒物质。

Glutamate ( Glu ) is known to be an excitatory neurotransmitter between inner hair cells ( IHC ) and the afferent neurons of the mammalian cochlea and to produce toxic effects upon the cochlea .

结论：（1）噪声性听损伤的ABR变化反映了声损伤始于外毛细胞，逐渐累及内毛细胞、听神经和脑干听觉通路的病变过程。

Conclusions ( 1 ) The ABR results of noise-induced hearing loss are correlated with a gradual pathological process from outer to inner hair cells , then to auditory nerve and brainstem auditory pathway .

照射后15～30d，外毛细胞纤毛除具有照射后早期变化外，还出现外毛细胞纤毛重组，以及内毛细胞边缘球形物隆起。

From 15 to 30d after radiation , reconstruction of cilia besides early changes , and ball shape materials on the side of inner hair cells were found .

从动物实验中可推断针刺在修复突发性耳聋者Corti器内毛细胞变性从而改善听力方面有积极的作用。

From the animal experiment can be inferred , acupuncture in the repair of sudden hearing loss of Corti inner hair cell degeneration , improve the hearing has positive effect .

目的：建立耳蜗器官体外培养模型，观察缺氧对体外培养耳蜗内毛细胞（IHC）及外毛细胞（OHC）的影响。

Objective To establish a practical model for Wistar rat cochlea organ cultivated in vitro and observe the effect of hypoxia on the inner hair cells ( IHC ) and outer hair cells ( OHC ) .

卡铂引起的灰鼠耳蜗内毛细胞缺损模式

Carboplatin-induced injury patterns of inner hair cells missing in chinchilla cochlea

内毛细胞缺损对噪声引起外毛细胞损害的潜在影响

Inner Hair Cell Missing Potentiates Noise Induced Outer Hair Cell Lesion

应用胰蛋白酶分离豚鼠耳蜗内毛细胞

Isolation of Cochlear Inner Hair Cells from Guinea Pigs by Trypsin

外毛细胞静纤毛副毛与列外内毛细胞。

Extra stereocilia on outer hair cell and extra inner hair cell .

内毛细胞为1排。

The inner hair cells form only a single row .

卡铂损伤灰鼠耳蜗内毛细胞对其耳蜗核神经元的影响

The Influence of Cochlea Injury on Cochlear Neucleus of Chinchilla

这些结果表明了内毛细胞或者第八对脑神经紊乱。

These results suggest a disorder of inner hair-cell and or eighth-nerve function .

噪声暴露后豚鼠耳蜗内毛细胞谷氨酸样免疫反应的改变

Effects of noise exposure on glutamate-like immunoreactivity of inner hair cells in guinea pigs

目的探讨庆大霉素对耳蜗内毛细胞带状突触数量的影响及其意义。

Objective To investigate the change of the ribbon synapses in inner hair cells by using gentamicin .

经鼓室注射庆大霉素后豚鼠前庭囊斑内毛细胞数的变化

Changes of Hair Cell Number in the Vestibular Utricles of Guinea Pigs Following Transtympanic Injection of Gentamycin

结论：听神经病的发病部位在耳蜗的内毛细胞。

Conclusion : Inner hair cells of cochlea is the site of pathological changes of auditory neuropathy .

提示在内毛细胞变性之前.卡铂可通过抑制内毛细胞的脱氢酶干扰其能量的代谢。

The results indicate that energy metabolism of the inner hair cells could be disturbed before hair cell degeneration .

螺旋器外毛细胞坏死较多，而内毛细胞及支持细胞病变较轻。

The outer hair cells in Corti 's organ were destroyed to a greater extent while inner hair cells and supporting elements were well preserved .

15年前，你的叔叔比尔是某位研究麻雀耳内毛细胞再生的著名学者的实验室里的高年级博士班学生。

15 years ago , your Uncle Bill was a senior graduate student in the lab of a famous researcher studying hair cell regeneration in sparrows .

内毛细胞、外毛细胞从立方体状渐分化为烧瓶状、试管状。

The inner hair cell ( IHC ) and outer hair cell ( OHC ) differentiated from shape of cube to flask and test tube respectively .

外毛细胞静纤毛束转位，静纤毛副毛与列外内毛细胞是遗传变异引起的。

The rotation of stereociliary bundles and extra stereocilia on the outer hair cell as well as the extra inner hair cell are induced by genetic variation .

结果：将卡铂耳中毒灰鼠的耳蜗标本与正常灰鼠进行比较，显示内毛细胞，神经纤维和螺旋神经节的损失百分比基本一致。

Results : Compared to normal ears , the carboplatin treated ears showed missing hair cells , nerve fibers and spiral ganglion cells , with the same percentage of loss at different levels .

提前30天给12只灰鼠按照100mg/kg的剂量腹腔注射卡铂，以达到预先选择性破坏其内毛细胞的目的。

12 chinchillas were injected with carboplatin ( 100 mg / kg , IP ) to eliminate inner hair cells . Six of them were terminated 30 days post-carboplatin as carboplatin control group .

谷氨酸由内毛细胞释放到突触间隙中，被支持细胞膜上的谷氨酸&天冬氨酸转运体转运进入支持细胞，在谷氨酰胺合成酶作用下转变为谷氨酰胺并被释放到细胞外。

Glutamate is released from the inner hair cells , and taken up by supporting cells through the glutamate transporter ( GLAST ) . Glutamate is converted to glutamine ( Gln ) by glutamine synthetase ( GS ) and then transferred to inner hair cells .

方法将3、13、28、43d龄罗曼小鸡用4000Hz半周正弦波刺激进行ABR测试后，采用透射电镜观察其耳蜗近端0.4～0.8mm区域内的毛细胞神经支配。

Methods After the measurement of ABR , the innervation on cochlea hair cells in 3,13,28,43 days'old chickens was observed by using transmission electron microscope .