免疫性疾病

结论MS是一种涉及中枢神经系统多种细胞的复杂免疫性疾病，可能与病毒感染有关。

Conclusion MS is a complex immunological disease in which many kinds of cells of the CNS take part in and may be related to the infection of virus of the CNS .

SEB可能主要活化银屑病患者hl细胞分泌IFN－Y、IL－18，银屑病为hl细胞介导的免疫性疾病。

5 % SEB may stimulate ThI cell in patients with psoriasis to secrete IFN-y > IL-18 , and psoriasis is an immunological disease mediated by Thl cell .

检测血清B因子在自身免疫性疾病中的意义

Significance of Serum Factor B in Autoimmune Disease

B淋巴细胞活化因子及其受体的发现在一定程度上促进了对自身免疫性疾病的研究。

The found of B lymphocytes activating factor and its receptors promote the researches about autoimmune hepatitis in certain degree .

重症肌无力（MG）是神经肌肉接头损害为主的自身免疫性疾病，其发病机理仍不清楚，一般认为遗传和环境因素共同作用的结果。

Objective : Myasthenia gravis ( MG ) is a neuromuscular disorder of autoimmune disease .

DNA甲基化异常可影响某些基因的表达，导致自身免疫性疾病的发生发展。

Abnormal DNA methylation can influence the expression of certain genes , inducing occurrence and development in autoimmune diseases .

另外，TALL1在转基因鼠中的过量表达可引起严重的B细胞增生以及与狼疮有关的自身免疫性疾病。

Moreover , the overexpression of TALL 1 in transgenic mice can result in severe B cell hyperplasia and autoimmune lupus like disease .

多胺改变了染色体的正常结构，干扰了DNA的甲基化过程，在自身免疫性疾病中的发病作用近来引起了人们的关注。

Polyamines change structure of chromosome and interfere with DNA methylation process , which is involved in the pathogenesis of autoimmune diseases .

Toll样受体在自身免疫性疾病中的作用机制研究现状

Research status of the mechanism of action about toll-like receptors in autoimmune disease

Tim基因家族及其与自身免疫性疾病和过敏性疾病的关系

Relationship between the TIM Gene Family and with Autoimmune and Allergic Diseases

系统性红斑狼疮（SLE）属于自身免疫性疾病。

Systemic lupus erythematosus is belong to autoimmune disease .

自体纯化CD（34）~+细胞移植治疗严重自身免疫性疾病的初步研究

A preliminary study on the treatment of severe autoimmune disease with autologous peripheral CD_ ( 34 ) ~ + cell transplantation

合并自身免疫性疾病患者MDS的分型以环形铁粒幼细胞性难治性贫血（RAS）最多见（4例）。

The commonest MDS was refractory anemia with ringed sideroblasts ( RAS ) .

应用TCRVβ基因谱分析血液病与免疫性疾病的T细胞克隆性

T Cell Clonality in Hematological Disease and Autoimmune Disease Using Analysis of TCR V β Gene Repertoire

Graves病（简称GD）是一种常见的自身免疫性疾病。

Objective Graves'diease ( GD ) is a kind of normal autoimmune thyroid disorder .

多发性硬化症与自身免疫性疾病：意大利东北部人群流行病学与HLA-DR之间的联系

Multiple sclerosis and autoimmune diseases : Epidemiology and HLA-DR association in North-east Italy

提示对于存在DC过度活化的一些自身免疫性疾病的治疗中，CCK-8可能是一种潜在的有效治疗因子。

Taken together , CCK-8 might be a potential therapeutic agent for autoimmune diseases with excessive activation of DCs .

应大力鼓励开展有关MMF与自身免疫性疾病之间潜在相关性的研究。

Research on the potential association with autoimmune diseases was strongly encouraged .

大疱性类天疱疮（Bullouspemphigoid，BP）是一种自身免疫性疾病，好发于老年人，组织病理为表皮下水疱。

Bullous pemphigoid ( BP ) is an autoimmue disease , which mainly affects the elderly .

结果60例MDS患者中，5例合并自身免疫性疾病，其中格雷夫斯病3例；

Results 5 of 60 MDS patients had AID , of which 3 had Graves ' disease .

白癜风的遗传特性以及白癜风患者常常伴发其他自身免疫性疾病，促使国内外学者研究HLA与白癜风的相关性。

The inherited nature of vitiligo and its frequent association with autoimmune diseases have prompted studies on the association between HLA and vitiligo .

TAO的发病机制尚未完全明了，但该病是一种免疫性疾病的概念已得到普遍公认，其发病是遗传因素与环境因素综合作用所致。

TAO is generally considered to have an autoimmune etiology and is thought to result from a complex interplay of genetic and environmental factors .

目的探讨血清葡萄糖-6-磷酸异构酶（GPI）水平与各种自身免疫性疾病（AID）的关系。

Objective To investigate the relationship between glucose - 6 - phosphate isomerase ( GPI ) and autoimmune disease ( AID ) .

此外，有多项研究表明Mal的自然变异跟一些免疫性疾病有关。

Recently , several studies have associated natural variants of Mal with various infectious diseases .

研究背景系统性红斑狼疮（Systemiclupuserythematosus，SLE）是一种典型的自身免疫性疾病，其临床特征是产生大量自身抗体和多系统、器官受累。

Background Systemic lupus erythematosus ( SLE ) is prototype of autoimmune disease characterized by high level of autoantibody production and multiple organ systems involvement .

进一步研究显示，MBL基因缺陷在感染性和自身免疫性疾病中发挥作用。

MBL deficiency is believed to play an important role in infectious and autoimmune disease .

幼年特发性关节炎（JIA）是儿童时期致残率最高的慢性自身免疫性疾病，至今病因不明。

Juvenile idiopathic arthritis ( JIA ) is a chronic autoimmune disease in childhood with high incidence of disability . The etiology is still unknown .

ANA滴度、抗ds-DNA滴度检测与自身免疫性疾病相关性及临床应用价值探讨

Detection of ANA 、 ds-DNA concentration and its correlation with diseases and clinical application

而未被清除的凋亡细胞会积聚诱发二次坏死，细胞质膜破裂释放出大量内容物，如核小体碎片、DNA、蛋白质、组蛋白成分，引发炎症反应及自身免疫性疾病。

Accumulation of uncleared apoptotic cells results in " secondary necrosis " and the release of cytoplasmic content , such as pieces of nucleosome , DNA , protein , histone composition , causing inflammation and autoimmune diseases .

类风湿性关节炎（Rheumatoidarthritis，RA）是一种常见且致残率极高的严重危害人类身心健康的系统性自身免疫性疾病。

Rheumatoid arthritis ( RA ) is one of the most common systemic autoimmune diseases with high deformity , which is seriously harmful to the human health .