伤寒沙门菌

伤寒沙门菌基因组DNA芯片基因表达谱分析技术的建立与优化

Development and optimization of DNA microarray-based Salmonella enterica serovar Typhi gene expression profiling

伤寒沙门菌基因组DNA芯片的制备与基因表达谱分析应用

Preparation of Salmonella enterica Serovar Typhi Genomic DNA Microarrays for Gene Expression Profiling Analysis

携带幽门螺杆菌尿素酶B亚单位的重组减毒鼠伤寒沙门菌核酸疫苗的构建

Construction of a recombinant attenuated Salmonella typhimurium nucleic acid vaccine carrying Helicobacter pylori urease B subunit

抗伤寒沙门菌SOD血清的制备及其免疫保护作用的研究

Preparation of anti-Salmonella typhi Fe-SOD and its immuno protection

甲型副伤寒沙门菌质粒DNA图谱与耐药性的关系

To determine and analyze the relation of plasmid DNA printing and drug resistance of 150 strains of S. Paratyphi A

副溶血性弧菌全基因组DNA芯片和比较基因组学研究伤寒沙门菌基因组DNA芯片基因表达谱分析技术的建立与优化

Comparative and Evolutionary Genomic Analysis of Vibrio Parahaemolyticus Development and optimization of DNA microarray-based Salmonella enterica serovar Typhi gene expression profiling

目的制备抗伤寒沙门菌FeSOD血清，研究其免疫保护作用，探讨SOD与沙门菌毒力的关系。

Objective To prepare the anti Salmonella typhi Fe SOD and to study the immuno protection of this antiserum .

广西伤寒沙门菌16SRRNA的基因多态性分析

Analysis of genomic diversities of 16s rRNA of salmonella typhi in Guangxi

贵州省伤寒沙门菌分离株16s核糖体基因型的多态性及其流行病学意义

Diversity of 16s rDNA ribotypes of the Salmonella typhi strains isolated in Guizhou province

目的探讨伤寒沙门菌Vi抗原作为毒力因子在致病机理中的作用。

Objective To research the role of Vi antigen of S.typhi as a virulence factor in pathogenic mechanisms of S.typhi .

目的研究以减毒鼠伤寒沙门菌为载体构建的重组幽门螺杆菌（Hp）疫苗诱导小鼠产生保护性免疫应答的机制。

Objective To study the protective immune response induced by attenuated Salmonella typhimurium expressing Helicobacter pylori ( H. pylori ) antigens in mice .

Vi抗原影响产肠毒素大肠杆菌菌毛在人伤寒沙门菌表面的装配

Effect of Vi antigen on assembly of colonization factor antigens from enterotoxigenic Escherichia coli on the cell surface of Salmonella typhi

贵州省2000年甲型副伤寒沙门菌分离株16SRRNA基因型分析

Analysis on 16s rRNA Ribotype of Salmonella paratyphi A Strains Isolated from Guizhou Province , 2000

方法对伤寒沙门菌CWDMs染色体的特异性PCR扩增产物进行限制性内切酶谱分析。

Methods PCR products of the chromosome DNA of the CWDMs were analysed by restriction zymogram .

2007年四川省鼠伤寒沙门菌PFGE分型及溯源

PFGE-typing of Salmonella Typhimurium Isolates for Source Identification in Sichuan Province , 2007

PCR快速检测甲型副伤寒沙门菌鞭毛抗原H-a研究

A Study on the Rapid Detection of Flagellum Antigen H-a of S. Paratyphi A by PCR

背景：幽门螺杆菌（H.pylori）是慢性活动性胃炎和消化性溃疡的重要致病菌，以减毒鼠伤寒沙门菌为载体构建活疫苗已成为探索新型H。

Background : Helicobacter pylori ( H. pylori ) is an important pathogen of chronic active gastritis and peptic ulcer .

云南省玉溪市甲型副伤寒沙门菌PFGE数据库的建立及其应用

Establishment and application of PFGE database on Salmonella enterica serotype Paratyphi A in Yuxi , Yunnan

结果PMA分化的THP-1细胞内化和杀伤Vi阴性伤寒沙门菌的活性明显高于内化和杀伤Vi阳性伤寒沙门菌的活性。

Results Vi negative S.typhi strains were internalized and killed significantly by PMA differentiated THP-1 cells by contrast to Vi positive S.typhi strains .

目的了解细胞壁缺陷对伤寒沙门菌苹果酸脱氢酶（MDH）活性的影响。

Objective To understand the activity of MDH and which would by influenced deficiency of cell wall .

伤寒沙门菌耐药质粒pR（ST98）spv毒力基因的研究

Identification and molecular analysis of Salmonella plasmid virulence genes ( spv ) on antibiotic resistance plasmid pR_ ( ST98 ) from S.typhi

伤寒沙门菌质粒pR（ST98）spv毒力基因与树突状细胞在免疫反应中关系的研究

Study on the Relationship between spv Gene on Salmonella Typhi Plasmid pR _ ( ST98 ) and the Dendritic Cells in Immune Response

方法：应用鼠伤寒沙门菌回复突变实验（Ames实验）、哺乳动物培养细胞染色体畸变（ChromosomeAberration，CA）实验、小鼠微核（Micronucleus，MN）实验和哺乳动物骨髓细胞CA实验。

Method : salmonella typhimurium mutagenicity test ( Ames test ), chromosome aberration ( CA ) test of cultivated cells of mammalian , micronucleus test in mice and mammalian bone marrow CA test were used .

目的：探讨鼠伤寒沙门菌的L型变异对噬菌体敏感性的影响。

Objective : To investigated the effect on phage sensitivity resulting from the Lforms variation of Salmonella typhimurium .

AcrAB-TolC电泵系统介导的鼠伤寒沙门菌多重耐药机理研究

Mechanism of AcrAB-TolC system mediated multiple antimicrobial resistance in Salmonella typhimurium

伤寒沙门菌mig-14基因功能研究

Research on the Function of mig-14 Gene in Salmonella Enterica Serovar Typhi

目的运用脉冲场凝胶（PFGE）电泳研究广东省伤寒沙门菌的分子流行病学。

Objective To molecular epidemiological study on the typing of Salmonella typhi in Guangdong province by the tech - nique of pulsed-field gel electrophoresis ( PFGE ) .

淋球菌膜抗原CppB基因的克隆及在大肠杆菌和减毒鼠伤寒沙门菌中的表达

Cloning of the Gonococcal CppB Antigen Gene and its Expression in E. coli and Attenuated S.typhimurium

方法采用Dot-ELISA测定伤寒沙门菌包膜抗原V、菌体抗原O和鞭毛抗原Hd的特异性抗体，并与肥达氏反应相比较。

Methods A Dot-ELISA method was used to determine the specific antibodies of envelope antigen , O antigen and H d antigen in Salmonella . Then the results were compared with the results of Widal 's reaction .

金黄色葡萄球菌和大肠埃希菌对萘啶酸和诺氟沙星的耐药升至50%以上，甲型副伤寒沙门菌则高达96%～97%，对氨苄西林、头孢唑林也都有明显升高（P0.01）；

Staphylococcus aureus and Escherichia coli resistant to nalidixic acid and norfloxacin were above 50 % , while Salmonella paratyphi A was 96 97 % , whose drug resistance to ampicillin and cefazolin had an obvious rise also ( P0.01 );