伤害性刺激

VEGF在神经病理性疼痛大鼠脊髓的表达及其对伤害性刺激反应的易化作用

The Expressions of VEGF in the Spinal Cords of Rats with Neuropathic Pain and the Facilitating Effects on Noxious Stimuli

结果（1）伤害性刺激使大鼠丘脑PF的PEN诱发放电频率增加；

Results ( 1 ) When the noxious stimuli were administered , the frequency of evoked discharge of PEN was increased ;

P物质具有强大的血管扩张活性，其参与皮肤伤害性刺激的感受与局部血管功能的调节。

P-substance has strong vasodilative activity and is involved in the sensation of the skin to traumatic stimulation and the modulation of local vascular function .

外周P物质受体介导伤害性刺激所致脊髓背角c-fos基因的表达

Peripheral substance P receptor mediating c-fos gene expression in the spinal dorsal horn induced by peripheral noxious stimulation

胃伤害性刺激对大鼠下丘脑乳头体前区内SPmRNA阳性神经元的影响

Noxious stimulation to stomach effects on neurons containing SP mRNA in premamillary region of rat hypothalamus

后角CGRP可能与伤害性刺激传导有关。

CGRP in posterior horn may be related to noxious stimulation conduction .

内脏伤害性刺激后Fos在大鼠脑内NOS阳性神经元内的表达

Expression of Fos in NOS-positive neurons in rat brain following visceral noxious stimulation

方法：选用SD大鼠，采用直结肠扩张（CRD）作为内脏的伤害性刺激。

Methods In SD rats CRD was used as noxious visceral stimuli .

大鼠牙髓伤害性刺激诱导延髓内Fos表达

Noxious dental pulp stimulation induced Fos expression in the medulla oblongata of the rat

大鼠腹膜伤害性刺激c-fos在中枢神经系统表达的实验研究

Empirical study of the rat peritoneal noxious stimulation inducing expression of c-fos in central nervous system

大鼠胃肠道伤害性刺激引起的中枢神经系统c-fos表达

C-fos expression within central nervous system of the rat following gastrointestinal ( visceral ) noxious stimulation

伤害性刺激电针后中缝背核生长抑素mRNA的表达及其与5-HT的共存

Expression of SOM mRNA and Coexistence of SOM mRNA and 5-HT in Nucleus Raphe Dorsalis Following Noxious Stimulation and Electroacupuncture Analgesia

鼠尾伤害性刺激与颧髎穴电针后弓状核-导水管周围灰质-延髓头端腹内侧区的前脑啡肽原mRNA的表达及与Fos蛋白共存

Expression of preproenkephalin mRNA and its coexistence with FOS in rat ar-pag-rvm following tail nociceptive stimulation and acupuncture in Quanliao point

胃伤害性刺激诱导大鼠脑干星形胶质细胞GFAP蛋白表达及其与神经元的关系

Expression of GFAP in rat brain stem astrocytes induced by stomachic nociception and relationship to neurons

吗啡－3－葡糖苷酸（M3G）对伤害性刺激诱导大鼠脊髓c－fos表达的影响

Morphine-3-glucuronide ( m3g ) potentiates noxious stimulus-evoked FOS protein-like immunoreactivity in the rat spinal cord

胃肠道伤害性刺激诱导中缝背核触液神经元Fos表达

Gastrointestinal noxious stimulation induced expression of Fos protein in the cerebrospinal fluid contacting neurons of dorsal raphe nucleus

大鼠脑干内向杏仁中央核投射的神经元对胃肠道伤害性刺激的FOS表达

The gastrointestinal noxious stimulation induced Fos expression of brainstem neurons projecting to the central amygdaloid nucleus in the rat

外周伤害性刺激后颈髓和三叉神经脊束核尾侧亚核中向中缝背核投射神经元的c-fos表达

Peripheral noxious stimulation-induced c-fos expression in neurons of cervical cord and caudal spinal trigeminal nucleus projection to the dorsal raphe nucleus

吗啡对非伤害性刺激后CCI大鼠脊髓c-fos表达的影响

Effect of morphine on expression of c-fos induced by innoxious touch-stimulus in the spinal cord in CCI rat

结论：GIRI的伤害性刺激影响了PVN、NTS的功能。

Conclusion : The function of PVN and NTS could be affected by the GI / RI noxious stimulation .

大鼠延髓内脏带向杏仁核投射的儿茶酚胺神经元对内脏伤害性刺激的FOS表达

Visceral noxious stimulation induced Fos expression of catecholaminergic neurons in the " medullary visceral zone " projecting to the central amygdaloid nucleus

电生理研究显示ACC部分神经元对伤害性刺激或预示伤害性刺激的环境信息产生反应。PET研究表明，伤害性刺激和疼痛引起的不愉快可以激活ACC。

Electrophysiological studies showed that some neurons within the ACC responded to either noxious stimulus per se or environmental cues that predict a painful stimulus .

大鼠延髓至下丘脑室旁核的儿茶酚胺能投射神经元在胃伤害性刺激后的FOS表达

Catecholaminergic neurons in medullary projecting to the paraventricular nucleus of the hypothalamus display Fos expression visceral noxious stimulation of stomach in the rat

结论大鼠磨牙移动时对牙齿产生伤害性刺激，引起牙髓末梢神经兴奋大量释放CGRP等神经肽，导致牙髓神经纤维中CGRP含量发生动态变化。

Conclusion The rat tooth movement stimulates the pulp nerves to release CGRP , which cause the variation of CGRP in the rat tooth pulp .

胃肠道伤害性刺激引起大鼠孤束核与中脑导水管周围灰质神经元表达FOS

Reciprocal projection neurons between the midbrain periaqueductal gray and nucleus of the solitary tract express FOS after noxious stimulation of the stomach and intestines in the rat

大鼠孤束核和延髓腹外侧区至下丘脑外侧区的儿茶酚胺能投射神经元在胃伤害性刺激后的FOS表达

Visceral noxious stimulation of stomach induced Fos expression in catecholaminergic neurons of the nucleus tractus solitarii and ventrolateral medulla projecting to the lateral hypothalamic area in the rat

伤害性刺激使痛兴奋神经元（PEN）诱发放电频率增加，使痛抑制神经元（PIN）诱发放电频率降低，并出现完全抑制时程，两类神经元相互配合活动；

When the noxious stimuli were administered , the frequency of induced discharge of pain excited neuron ( PEN ) was increased while the frequency of pain inhibited neuron was decreased and the perfectibility inhibition was presented .

目的观察正常和胃伤害性刺激大鼠下丘脑乳头体前区（PMH）内P物质（SP）mRNA阳性神经元的分布和变化。

AIM To observe the distribution and changes of neurons expressing substance P ( SP ) mRNA in the rat premamillary region of the hypothalamus ( PMH ) by visceral noxious stimulation to the stomach .

上述结果提示：（1）Vc及MRF内直接向VPM投射的部分神经元感受面口部伤害性刺激信息；

These results suggested that : ( 1 ) There were some neurons in the Vc and MRF receiving orofacial noxious information and projecting directly to the VPM ;

文中对缺蛋再灌引起CFos-及ODC基因表达的机制进行了分析与讨论，并提出神经元应激状态这一概念以描述神经元对伤害性刺激的反应历程。

In this article , we analysed the mechanism that recirculation after ischemia induces c-fos and ODC genes expression , and proposed the concept - neuronal stress state to describe neuronal response to destructive stimulation .