乙酰胆碱受体抗体

由于抗乙酰胆碱受体抗体的异质性，B淋巴细胞集合程度并不能反映临床症状的轻重。

The degree of B lymphocyte subgroup aggregation can not truly reflect clinical status because of the heterogenity of antibody against acetylcholine receptor .

经GC治疗后，大多数患者抗乙酰胆碱受体抗体滴度较治疗前明显降低。

Anti - acetylcholine receptor ( AChRAb ) titers were markedly decreased after GC therapy .

结论MG患者的自主神经功能障碍可能与乙酰胆碱受体抗体侵犯平滑肌和交感神经有关。

Conclusions It is related dysfunction of autonomic to the antibodies of acetylcholine receptor which involve on smooth muscle and sympathetic nerve in MG patients .

重症肌无力中乙酰胆碱受体抗体是针对N型乙酰胆碱受体（nAchR）糖蛋白的多克隆抗体。

In myasthenia gravis acetylcholine receptors antibody is n-type acetylcholine receptors ( nAchR ) glycoprotein polyclonal antibody .

重症肌无力（MG）是由乙酰胆碱受体抗体介导的细胞免疫依赖性和补体参与的神经肌接头部位的自身免疫性疾病，免疫应答异常是其发病本质。

Myasthenia gravis ( MG ) is cell immune-dependent and complement-participative autoimmune neuromuscular disease mediated by antibodies against the nicotinic acetylcholine receptor ( AChR ), Its essential pathogenesis is immune response dysfunction .

ABC-ELISA测定重症肌无力患者血清抗乙酰胆碱受体抗体水平的研究

Detection of anti-AChR antibody in myasthenia gravis patients with ABC-ELISA

目的采用中药黄芪复方调节重症肌无力（Myastheniagravis，MG）患者血清乙酰胆碱受体抗体（acetylcholinereceptorantibody，AChRAb）水平，以探讨其治疗MG的可能作用机制。

Objective To observe the mechanism of Huangqi compound by regulating the acetylcholine receptor antibody ( AChRAb ) level in blood of myasthenia gravis ( MG ) patients .

目的研究乙酰胆碱受体抗体（AChRAb）IgG对大鼠隔斜角带核区胆碱能神经元的损害作用。

Objective To investigate the injuries of the septo-diagonal bands cholinergic neurons of rats caused by acetylcholine-receptor antibody ( AChRAb ) IgG .

方法ELISA法检测32例MG患者在糖皮质激素治疗前和治疗3个月后的血清白细胞介素（IL）6和乙酰胆碱受体抗体（AChRab）水平。

Methods The sera interleukin ( IL ) - 6 and acetylcholine receptor antibody ( AChRab ) levels are measured with ELISA in 32 MG patients before and after treatment with glucocorticosteroid .

本实验为下一步构建AChRα四聚体并作为抗原检测乙酰胆碱受体抗体奠定了基础。

This experiment lays the foundation for constructing tetrameric AChR α to be used as antigen in the determination of anti-AChR antibodies .

目的探讨乙酰胆碱受体抗体（AchRab）IgG对大鼠隔-海马胆碱能系统的损害及对认知功能的影响。

Objective To investigate the injuries of the septo-hippocampal cholinergic system of rats caused by acetylcholine-receptor antibody ( AchRab ) IgG and the effects on cognitive functions of rats .

对100例临床确诊为重症肌无力（MG）、血清乙酰胆碱受体抗体阳性的患者进行血清可溶性白细胞介素-2受体（sIL－2R）检测。

In this report , soluble interleukin-2 receptor ( sIL-2 ) in sera of 100 myasthenia gravis ( MG ) patients was detected with ELISA , whose seral acetylcholine receptor antibody ( AchRab ) detection was positive .

方法：用ELISA方法检测34例重症肌无力病人、20例正常人和21例其他神经系统疾病病人血清中抗ω－芋螺毒素结合蛋白、抗突触前膜和抗乙酰胆碱受体抗体。

Methods : ELISA was used to test the antibodies to ω - conotoxin binding protein , pre-synaptic membrane ( Prsm ) and acetylcholine receptor ( AChR ) in sera from 34 MG patients , 20 healthy controls and 21 other neurological disorders ( OND ) .

目的：观察乙酰胆碱受体抗体（AChRab）脑室内注射对大鼠脑电图的影响，并探讨其发生机制。

Objective : To observe the effect of nicotinic acetylcholine receptor antibody ( AChRab ) on rats electroencephalography ( EEG ) and to try to investigate its mechanism .

75%的重症肌无力患者伴有胸腺异常，增生胸腺存在AChR特异反应性T、B细胞，胸腺瘤中存在着T细胞的分化，有乙酰胆碱受体抗体（AChRAb）滴度升高。

75 % of patients with myasthenia gravis have disorders in their thymus glands . There are specific response of T and B cells to AChR in hyperplasia thymus and differentiation of T cells with higher titer of AChRAb in thymoma .

重症肌无力患者的乙酰胆碱受体抗体和循环免疫复合物的研究

Studies on Acetylcholine Receptor Antibody and Circulating Immune Complex in Myasthenia Gravis

胸腺切除后血清乙酰胆碱受体抗体改变及与疗效关系

Correlations Between Clinical Effects and Changes in Serum Acetylcholine Receptor Antibody after Thymectomy

抗乙酰胆碱受体抗体的补体结合功能去除

Removal of Complement Binding Activity of an Anti-acetylcholine Receptor Antibody by Site Directed Mutagenesis

黄芪复方对重症肌无力患者血清乙酰胆碱受体抗体水平的影响

The Regulating Effects of Huangqi Compound on Acetylcholine Receptor Antibody in Myasthenia Gravis Patients

重症肌无力乙酰胆碱受体抗体与猴神经烟碱型乙酰胆碱受体之间的免疫结合反应

Immunoreactivity of acetylcholine receptor antibody from myasthenia gravis with monkey neuronal nicotinic acetylcholine receptor

重症肌无力的临床分型、电诊断及乙酰胆碱受体抗体的比较

Comparative Analysis of Clinical Classification , Electrodiagnosis and Antibody Titre of Acetylcholine Receptor in Myasthenia Gravis

乙酰胆碱受体抗体量与眼型重症肌无力病情关系的实验观察

Relationship between the contents of acetylcholine receptor antibody and patient 's condition of ocular myasthenia gravis

β-银环蛇毒素结合蛋白抗体和乙酰胆碱受体抗体亲和性及其在重症肌无力致病中的意义

Affinity Distribution of Antigen-Specific IgG in Rats Immunized with Acetylcholine Receptor and β - bungarotoxin Binding Protein

肌肉特异性酪氨酸激酶抗体与乙酰胆碱受体抗体阳性重症肌无力患者四肢与面肌的单纤维肌电图

Single-fiber electromyography in limb and facial muscles in muscle-specific kinase antibody and acetylcholine receptor antibody myasthenia gravis

单链抗体对重症肌无力致病性抗乙酰胆碱受体抗体的抑制

Inhibition of pathogenic antibodies to the binding of acetylcholine receptor by a single chain variable fragment in myasthenia gravis

乙酰胆碱受体抗体与大鼠中枢神经元烟碱型乙酰胆碱受体之间免疫结合反应

Immunoreaction between Acetylcholine Receptor Antibodies Purified from Myasthenia Gravis Sera and Neuronal Nicotinic Acetylcholine Receptors in Rats ' Central Nervous System

血清乙酰胆碱受体抗体、突触前膜抗体和胸腺瘤相关抗体与重症肌无力发病关系的研究

A Study on Correlation of Myasthenia Gravis with Seral Acetylcholine Receptor Antibody , Pre-synaptic Membrane Antibody , and Citric Acid Extract Antibody

固定液浓度与固定时间对人乙酰胆碱受体抗体与大鼠神经元-nAchR之间免疫结合反应的影响

Influence of the concentration of fixative and the time of fixation on the immunohistochemical reaction between the antibody against human AChR and rat nAChR

目的：制备出无补体结合功能的免疫球蛋白样抗乙酰胆碱受体抗体，用于重症肌无力的特异性免疫治疗。

Objective : To develop an immunoglobulin-like anti-acetylcholine receptor ( AChR ) antibody without complement-binding activity , which can be used in the specific immunotherapy for myasthenia gravis .

血清抗乙酰胆碱受体抗体阴性，重复神经刺激出现肌电图波幅低频递减，远端肌电图显示神经源性损害。

Electromyography ( EMG ) showed neurogenic features in the distal muscles and decrement response was showed with low frequency repetitive nerve stimuli . The acetylcholine receptor antibody test was negative .