血管紧张素转化酶抑制剂

目的建立高效毛细管电泳测定血管紧张素转化酶抑制剂captopril抑制活性的方法。

Aim To establish a method for determinate of the inhibitory activity of angiotensin-converting enzyme inhibitor captopril by high performance capillary electrophoresis .

目的探讨凋亡基因对大鼠心肌梗死的表达及血管紧张素转化酶抑制剂（ACEI）的干预作用。

Objective To investigate the expression of apoptosis - related genes in rats with myocardial infarction and effects of ACEI .

结果钙拮抗剂、肾上腺素受体阻滞药、血管紧张素转化酶抑制剂（ACEI）在用药金额、用药频度上分别占前三位。

Results The amount used DDDs of calcium antagonists , adrenergic receptor blockers and ACEI drugs were the head of three .

卡托普利（Cap）是血管紧张素转化酶抑制剂，是目前临床上用于治疗各种类型高血压病较为有效的常用药物之一。

Captopril ( Cap ) is one of the angiotensin converting enzyme inhibitor , Which is a commonly-used and relatively effective drug for the clinical treatment of different kinds of high blood pressure diseases .

研究血管紧张素转化酶抑制剂（ACEI）对沙土鼠缺血再灌注脑损伤的保护作用。

We investigated the protective effects of angiotensin converting enzyme inhibitor ( ACEI ) on ischemia reperfusion brain injury in a Mongolian gerbil model .

RAS系统的激活与二者的形成与发展密切相关，血管紧张素转化酶抑制剂（ACEI）能改善胰岛素的敏感性，降低血浆胰岛素水平。

RAS system activation is closely related to the formation and development between the two , angiotensin-converting enzyme inhibitors ( ACEI ) could improve insulin sensitivity , lower plasma insulin levels .

大型临床研究实验证实血管紧张素转化酶抑制剂（ACEI）可以通过多条途径保护血管内皮功能，从而改善动脉粥样硬化状态。

Large clinical studies have confirmed experimentally angiotensin converting into enzyme inhibitor ( ACEI ) can protect vascular endothelial function through various ways , thereby improving the atherosclerotic state .

目的：研究血管紧张素转化酶抑制剂（ACEI）苯那普利对原发性高血压（EH）患者肾功能储备（RFR）的影响。

Objective : To study the effects of benazepril ( ACEI ) on renal functional reserve ( RFR ) of patients with essential hypertension ( EH ) .

早期的临床研究显示，血管紧张素转化酶抑制剂（ACEI）可能减少恶性心律失常的发生而降低心肌肥厚，心衰病人死亡率。

Early clinical trials show that angiotensin-converting enzyme inhibitor ( ACEI ) could reduce the morbidity presumably caused by malignant arrhythmia in the patients with cardiac hypertrophy and heart failure .

目的观察犬急性心肌梗死（AMI）溶栓治疗时应用血管紧张素转化酶抑制剂（ACEI）对胰岛素敏感性的影响。

Objective To observe the effect of angiotensin-converting enzyme inhibitor ( ACEI ) on insulin sensiti - ( vity ) in dogs with acute myocardial infarction ( AMI ) after thrombolytic treatment .

结论（1）血管紧张素转化酶抑制剂（ACEI）和血管紧张素Ⅱ受体拮抗剂（ARB）均能减轻糖尿病大鼠的肾脏肥大，减少UPER。

Conclusion ( 1 ) Angiotension-converting enzyme inhibitor ( ACEI ) and angiotension ⅱ receptor blocker ( ARB ) can ameliorate renal hypertrophy and UPER in diabetic rats .

目的从蛋白质水平研究转化生长因子（TGFβ1）在梗阻性肾病中所起的作用及血管紧张素转化酶抑制剂-西那普利（Cilazapril）对其表达的影响。

Objective To evaluate the role of transforming growth factor β 1 ( TGF β 1 ) in obstructive nephropathy and the effect of an angiotension converting enzyme ( ACE ) inhibitor , cilazapril .

目的：观察慢性心力衰竭（心衰）患者应用血管紧张素转化酶抑制剂（ACEI）治疗中加用醛固酮受体拮抗剂螺内酯对血浆醛固酮和心功能的影响。

Objective : The aim of this study was to investigate the effects of extra spironolactone on the aldosterone ( Aldo ) level and heart function in patients with heart failure treated with angiotensin-converting enzyme inhibitor ( ACEI ) .

结论AngⅡ在DED大鼠血浆及海绵体组织中显著升高，在DED的发病中可能具有重要作用，血管紧张素转化酶抑制剂（ACEI）或AngⅡ受体拮抗剂有望成为治疗DED的重要方法之一。

Conclusion : Ang ⅱ may play an important role in the pathogenesis of DED , and the Ang ⅱ antagonist or inhibitor of the angiotensin-converting enzyme ( ACEI ) may become a therapeutic method for DED in the future .

本文简述了高血压病的现状与致病机理以及各种抗高血压药物的作用机制和研究进展，重点介绍了血管紧张素转化酶抑制剂（ACEI）的构效关系、药代动力学性质以及主要副作用。

The situation and nosogenesis of hypertension were described briefly in this paper . The action mechanism and development of antihypertensive drugs were also introduced , especially of the structure-activity relationships , pharmacokinetic properties and main side-effects of angiotensin converting enzyme inhibitors ( ACEI ) .

背景血管紧张素转化酶抑制剂（ACEI）引起干咳的机制尚不完全清楚，有报道认为可能是由一氧化氮（NO）介导的，而补充铁剂能减少NO的生成并能降低NO相关的细胞损害。

Background The mechanism of angiotensin converting enzyme inhibitor ( ACEI ) induced cough has not been fully elucidated . One of possible mechanisms is ACEI increase nitric oxide ( NO ) generation , iron supplementation can inhibit this increase and NO related cell damage .

亲和色谱法筛选中药中血管紧张素转化酶抑制剂

Screening of angiotensin converting enzyme inhibitors from traditional chinese Medicines by affinity chromatography

此外，服用他汀类药物和血管紧张素转化酶抑制剂也会出现类似效果。

A similar effect is seen with drugs such as statins and ACE inhibitors .

基于定量构效关系预测血管紧张素转化酶抑制剂活性

Activity Prediction of Angiotensin Converting Enzyme Inhibitors Based on the Quantitative Structure-Activity Relationship Method

缬沙坦在血管紧张素转化酶抑制剂不能耐受患者中的多中心临床试验

Multicenter trial of valsartan in patients of being intolerant of angiotensin converting enzymes inhibitor

第三代血管紧张素转化酶抑制剂盐酸喹那普利的合成研究

Studies on the Synthesis of Quinapril , the Third Generation Angiotensin Converting Enzyme Inhibitor

大豆蛋白体外酶解物中血管紧张素转化酶抑制剂活性肽研究

Study on angiotensin converting enzyme inhibitory peptides from digestion of soy protein in vitro

新型血管紧张素转化酶抑制剂的合成

Synthesis of new angiotensin converting enzyme inhibitors

脓毒症时大鼠心脏的变化及血管紧张素转化酶抑制剂的保护作用

The protective effects of angiotensin-converting enzyme inhibitor ( ACEI ) on the heart in sepsis rats

非甾醇类抗炎药物、磺胺药、血管紧张素转化酶抑制剂等老药也在血管形成中扮演新角色；

The role of nonsteroidal anti-inflammatory drugs , sulfonamides and angiotension converting enzyme inhibitors in tumor angiogenesis ;

术前用药需结合使用α肾上腺素能受体阻滞剂（酚苄明）和血管紧张素转化酶抑制剂（卡托普利）。

Preliminary preparation needed to use alpha-adrenergic blocking agent ( Phenoxybenzamine ) and angiotensin converting enzyme inhibitor ( Captopril ) .

急性心肌梗死后的老年患者应用不同血管紧张素转化酶抑制剂对死亡率的影响：是药物种类的影响吗？

Mortality rates in elderly patients who take different angiotensin-converting enzyme inhibitors after acute myocardial infarction : A class effect ?

对第二代血管紧张素转化酶抑制剂依那普利的药理作用及临床应用作一简要综述。

The purest of the writing is to summarize the pharmacal effect and clinical practice of the second angiotensin-converting enzyme inhibitors enalapril .

促红细胞生成素治疗肾性贫血的红细胞抵抗血管紧张素转化酶抑制剂合用的影响

The observation on the erythrocyte resistance during the erythropoiesis treating the anemia of chronic renal failure and the effect using angiotensin-converting enzyme inhibitor

近年来，许多学者对血管紧张素转化酶抑制剂抑制率的测定方法开展了大量的研究工作。

A lot of research work has been carried out about the analytical method for inhibitory activity of the angiotensin-converting enzyme in recent years .