致敏

肾移植受者HLA体液致敏因素

Factors resulting in HLA humoral sensitization in candidates of renal recipients

HLAⅡ类抗原是致敏的主要原因；

HLA class II antigens take main responsibility for sensitization .

以北京为例，春季最常见的致敏花粉包括榆树、杨树、白蜡、合欢树和白桦的花粉。

In Beijing , for example , the most common allergenic pollens in spring include those from the large-fruited elm tree , Cathay poplar , ash , acacia and white birch .

实验组行RFA+冻融抗原致敏DC治疗。

Experimental group was treated with RFA and antigen-pulsed DCs .

肝癌细胞裂解物致敏DC疫苗诱导的肿瘤特异抗瘤效应

The tumor specific anti - tumor effects mounted by hepatoma cell lysates pulsed DC

HPLC法测定纺织品中八种致敏禁用分散染料

Determination of Eight Banned Sensitizing Disperse Dyes in Textiles with HPLC

实时荧光PCR快速检测食品中致敏原芹菜成分

Rapid Detection of celery in Food by Real-Time PCR

结果：肿瘤抗原致敏DC能有效刺激同基因型T淋巴细胞增殖反应；

Result : The tumor antigen-pulsed DCs could effectively stimulate the proliferation of T cells .

以该肿瘤抗原致敏外周血DC，诱导T细胞转变为CTL；

T cells and DCs were separated from peripheral blood .

用MTT比色法检测DC疫苗刺激小鼠未致敏脾细胞的增殖。

Proliferation of non - sensitized splenocytes stimulated by transfected DC was calculated by MTT .

肿瘤抗原冲击致敏的IL-2基因修饰的巨噬细胞治疗肾癌的实验研究

Therapy of renal cancer with tumor antigen-pulsed , IL-2 gene-modified macrophages

建立了HPLC法测定纺织品中8种致敏禁用分散染料的方法。

A method for measuring eight banned sensitizing disperse dyes in textiles by HPLC was developed .

SEA致敏组和自然感染组各期虫卵肉芽肿内IgG抗体均呈阳性。

Immunohistochemical assay indicated IgG was positive in all granulomas of SEA sensitized group and cercariae infected group .

树突状细胞（Dendriticcells，DC）能够刺激并致敏初始T细胞和启动早期免疫反应而被认为是最重要的抗原呈递细胞。

Dendritic cells ( DC ) are specialized antigen-presenting cells that prime naive T cells to induce initial immune responses .

目前用DC进行肿瘤特异性主动免疫治疗主要有：1）应用肿瘤相关抗原（肽）体外致敏DC；

DC-based specific active immunotherapy include : 1 ) DC induced by tumor associated antigen ( peptide ) in vitro .

HBsAg致敏的树突状细胞体外抗乙型肝炎病毒的效应

Human CTLs-mediated anti-HBV effects of dendritic cells sensitized by HBsAg in vitro

方法：采用抗体致敏红细胞花环法和ELISA法对40例丙型肝炎患者T淋巴细胞亚群及抗-HCV-IgM进行检测。

Method : The T lymphocyte subsets and anti-HCV-IgM were detected by EA rosette and ELISA .

目的研究肝癌细胞裂解物致敏的树突状细胞（DC）疫苗诱导的体内、外抗瘤效应。

Objective To study the anti-tumor effects elicited by hepatoma cell lysates pulsed DC vaccine both in vitro and in vivo .

单克隆抗体固相致敏红细胞吸附技术检测HBsAg的研究

Study on SPASE for Detecting HBsAg with Monoclonal Antibodies

LC的主要生物学作用是在针对各种类型抗原而发生的皮肤免疫反应中提供致敏信号。

Its main biological function is to provide sensitization signals to various antigens .

应用致敏SPA菌体提高CAV/CPVPCR检出率的研究

Improvement of PCR detection rate of CAV / CPV in feces using sensitized Staphylococcus aureus

致敏DC诱导CTL特异性杀伤HL-60细胞的实验研究

Investigation on specific Anti-HL-60 cell reaction with CTL induced by sensitive dendritic cells

组胺H＿1受体拮抗剂特非那定对正常和致敏豚鼠气管螺旋条的作用

A study on the effect of terfenadine , a histamine H_1 receptor antagonist , on normal and sensitized guinea-pig tracheal spirals in vitro

衣霉素诱导的内质网应激可能在衣霉素对TRAIL的这种致敏性中发挥作用。

Tunicamycin-induced ER stress seems to play an important role in tunicamycin-mediated up-regulation of TRAIL receptors .

而卵清蛋白致敏激发并给予裸DNA组与卵清蛋白致敏激发组比较差异无显著性，表明裸DNA难以通过气道内注入在活体动物气道表达。

There is no significant difference between OVA group and DNA group , indicating that bare DNA is hard to express in the animals via airway .

HLA体液致敏与肾移植

HLA sensitization and renal transplantation

良好的HLA配型和CERG配型可提高致敏受者肾移植的成功率。

Improved HLA and CREG matching can heighten the chance of success for renal transplantation in sensitized recipients .

目的：观察经肿瘤细胞裂解物致敏的白细胞介素18（IL-18）基因修饰的树突状细胞（DC）体内诱导的抗肿瘤免疫应答反应。

Objective : To investigate the induction of antitumor immune response of tumor cell lysate sensitized interleukin 18 gene-modified DC .

目的变应性接触性皮炎（allergiccontactdermatitis，ACD）是T细胞介导的针对皮肤接触致敏原的免疫反应。

Objectives Allergic contact dermatitis ( ACD ) is a T cell-mediated cutaneous immune / inflammatory reaction to haptens .

结论：用OVA致敏、激发，可以成功建立小鼠慢性哮喘模型。

The research established the chronic asthma model of mice .