脂磷壁酸

目的研究双歧杆菌表面分子细胞壁肽聚糖（WPG）、脂磷壁酸（LTA）对LPS体内诱导小鼠胸腺细胞凋亡的调节。

Objective To investigate the regulation of Bifidobacterium bifidum surface molecules whole peptidoglycan ( WPG ), lipoteichoic acid ( LTA ) on apoptosis of murine thymocytes induced by LPS in vivo .

双歧杆菌是人和动物肠道内重要的生理菌，其表面分子脂磷壁酸（lipoteichoicacid，LTA）已被证实具有抗肿瘤作用，但其在逆转肿瘤免疫逃逸中的作用尚未见报道。

Bifidobacteria is one of important intestinal physiological bacterium of human and animals , and its surface molecule lipoteichoic acid ( LTA ) has been proven to have anti-tumor effects , but the role of LTA in reversal tumor immune escape has not been reported .

双歧杆菌脂磷壁酸对NF-κB在结肠癌细胞中表达的影响

Effect of lipoteichoic acid of Bifidobacterium on NF - κ B expression in colon cancer cells

双歧杆菌脂磷壁酸对衰老小鼠胸腺Bcl-2、Fas基因表达的影响

Effect of Lipoteichoic Acid from Bifidobacterium on Bcl-2 、 Fas Gene Expression in Aging Mice

双歧杆菌脂磷壁酸（lipoteichoicacid，LTA）具有延缓衰老作用，但其延缓衰老的机制尚不清楚。

Lipoteichoic acid of Bifidobacterium have anti-aging effect , but its mechanism is not clear enough .

本实验通过体外研究Toll样受体在结肠癌细胞凋亡前后的表达，探讨Toll样受体在双歧杆菌脂磷壁酸体外诱导结肠癌细胞凋亡信号转导通路中的作用。

In the topic , we do experiments on Toll-like receptors in order to study the signal transduction pathway of bifidobacterium lipoteichoic acid in inducing apoptosis of colon cancer cells .

目的探讨A组乙型链球菌（GAS）脂磷壁酸（LTA）提取方法及其在风湿热发病过程中的意义。

Objective To search for new method of extracting and purifying lipoteichoic acid ( LTA ) from group A streptococcus ( GAS ), and evaluate its significance in the pathogenesis of rheumatic fever .

除LPS外，CD14还介导肽聚糖（PGN）、脂磷壁酸（LTA）、脂蛋白等多种病原体成分与细胞的反应，它是天然免疫中重要的模式识别分子。

Thus , CD 14 is an important component of the innate immune system and can be defined as pattern recognition receptor .

双歧杆菌脂磷壁酸激活巨噬细胞活性机制的研究

Study on the activating mechanisms of macrophages by LTA of Bifidobacteria

双歧杆菌脂磷壁酸延缓细胞衰老的作用机制

Effect and mechanism of lipoteichoic acid of Bifidobacterium on delaying cell aing

以脂磷壁酸为靶点的新抗筛选模型的建立和应用

Establishment and application of a novel anti-microbial screen model targeted on lipoteichoic acid

脂磷壁酸的提取纯化及抑菌活性研究

Study on extraction and anti-bacterial activity of Lipoteichoic acid

A组β溶血性链球菌脂磷壁酸抗体在风湿热诊断中的意义

Significance of antibody to group A streptococcal lipoteichoic acid in diagnosis of rheumatic fever

双歧杆菌脂磷壁酸对化疗荷瘤小鼠免疫功能的影响

Effect of lipoteichoic acid of Bifidobacterium on immune function of tumor-bearing mice with chemotherapy

因此，进一步证明冷酚法提取并通过凝胶色谱层析能够得到纯度较高的脂磷壁酸。

Therefore , phenol extraction and gel chromatography can get the higher purity lipoteichoic acid .

双歧杆菌脂磷壁酸联合5-氟尿嘧啶抗肿瘤的实验研究

The Experimental Study on Anti-Tumor Effects of Lipoteichoic Acid of Bifidobacterium in Combination with 5-Fluorouracil

双歧杆菌脂磷壁酸与5-氟尿嘧啶体内联用对肿瘤细胞凋亡的影响

Effect of lipoteichoic acid of Bifidobacterium on apoptosis of tumor cells in tumor-bearing in vivo

双歧杆菌脂磷壁酸抗体的制备及其在双歧制品中的检测应用

Production of Anti-Bifidobacteria Lipoteichoic Acid Antibodies and Their Application in the Detection of Bifidus Products

脂磷壁酸－葡糖基转移酶－葡聚糖相互作用对口腔链球菌粘附作用的影响

The effects of interaction of LTA , GTF and glucan on the adherence of oral streptococci

脂磷壁酸佐剂和蜂胶佐剂辅助P3035刺激产生的细胞免疫应答及免疫保护力低于拟菌颗粒佐剂和福氏完全佐剂。

The immune response and protective immunity induced by LTA adjuvant and propolis extra adjuvant were lower than that induced by bacteria - like particles adjuvant and CFA .