脂蛋白脂肪酶

脂蛋白脂肪酶基因突变的研究

Study on LPL Gene Mutations

应用RNA干扰技术体外抑制脂蛋白脂肪酶基因的表达

In Vitro Inhibition of Lipoprotein Lipase Gene Expression by RNA Interference

目的：获得STR位点脂蛋白脂肪酶基因（LPL）在浙南汉族群体中的等位基因频率。

Objective : To get the polymorphism of LPL in South Zhejiang Han population .

脂蛋白脂肪酶（LPL）在血浆脂蛋白的代谢中发挥了重要的作用。

Lipoprotein Lipase ( LPL ) plays an important role in plasma lipoprotein metabolism .

目的探讨国人脂蛋白脂肪酶基因外显子9特别是Ser447→stop变异对血脂水平的影响。

Aim To screen the mutations in lipoprotein lipase ( LPL ) gene exon 9 and to investigate the effect of mutation on triglyceride ( TG ) and high density lipoprotein cholesterol ( HDLC ) level .

脂蛋白脂肪酶Pro~（207）→Leu基因突变致高甘油三酯血症

Mutation of Lipoprotein Lipase Gene Pro ~ ( 207 ) Leu Result in Hypertriglyceridemia

合成药NO-1886是脂蛋白脂肪酶（LPL）的激动剂，能降低血浆甘油三酯（TG）并升高高密度脂蛋白胆固醇（HDL-c）水平。

Synthetic compound NO-1886 is a lipoprotein lipase activator which lowers plasma triglycerides and elevates high-density lipoprotein cholesterol ( HDL-C ) .

目的探讨肝脂酶（HL）和脂蛋白脂肪酶（LPL）在脂肪肝发病中的作用。

Objective To determine the possible role of hepatic lipase ( HL ) and lipoprotein lipase ( LPL ) in the pathogenesis of fatty liver .

NO-1886对过氧化体增殖物激活型受体、脂蛋白脂肪酶和肿瘤坏死因子α基因表达的影响

Effects of NO-1886 on Expression of Peroxisome Proliferator-Activated Receptor , Lipoprotein Lipase and Tumor Necrosis Factor - α

脂蛋白脂肪酶（lipoproteinlipase，LPL）是血浆脂蛋白代谢的关键酶，其可将乳糜微粒和极低密度脂蛋白中的甘油三酯水解为甘油和游离脂肪酸供组织利用。

Lipoprotein lipase ( LPL ) is a key enzyme of lipid metabolism , its major function is the hydrolysis of the core triglycerides of circulating chylomicrons and very low density lipoproteins .

目的：筛查国人脂蛋白脂肪酶（LPL）基因的突变，并探讨其与高甘油三酯血症的关系。

Objective : To screen mutations of the lipoprotein lipase gene in Chinese population and to study the possible effects of the mutations on serum lipids .

脂解产生的游离脂肪酸的放射活性与标本中脂肪酶的活性成正比。表达人脂蛋白脂肪酶的重组腺病毒感染培养的293A细胞后，肝素后培养液中表达很高的脂蛋白脂肪酶活性。

Results There was high LPL activity expression in cultured 293A cells infected with recombinant adenovirus encoding human LPL .

低氧训练对大鼠脂蛋白脂肪酶和甘油三酯影响的实验研究

The Effect of Hypoxic Training to Triglyceride and Lipoprotein Lipase in Rat

放射性同位素标记法检测脂蛋白脂肪酶活性及其应用

Determination of Lipoprotein Lipase Activity Using Radioactive Substrate Emulsion and Its Application

脂蛋白脂肪酶基因敲除小鼠脂代谢动态观察

Lipid metabolism in lipoprotein lipase gene knockout heterozygous mice

肝脂酶、脂蛋白脂肪酶在脂肪肝发病中的作用

The role of hepatic lipase and lipoprotein lipase in the pathogenesis of fatty liver

基因多态性对血浆脂蛋白脂肪酶浓度及甘油三酯水平的影响

The effect of lipoprotein lipase ( LPL ) polymorphism on plasma LPL concentration and triglyceride

脂蛋白脂肪酶在巨噬细胞代谢正常极低密度脂蛋白中的作用

The Role of Lipoprotein Lipase in The Metabolism of Normal Very Low Density Lipoproteins by Macrophages

胰岛素和甲状腺素对家兔脂蛋白脂肪酶和肝脂酶活性的影响

Effect of Insulin and Thyroxin on Lipoprotein Lipase Activity and Hepatic Triglyceride Lipase Activity in Rabbits

实验性动脉粥样硬化家兔主动脉脂蛋白脂肪酶活性与胆固醇沉积量的关系

The Relation of LPL Activity to the Content of Cholesterol in the Aorta of Experimental Atherosclerosis Rabbits

喂饲1周后各组大鼠激素敏感脂肪酶和脂蛋白脂肪酶活性。

The activity of hormone sensitive lipase and lipoprotein lipase ( LPL ) of rats in each group after feeding 1 week .

β2肾上腺素能受体和脂蛋白脂肪酶基因多态性作为自发性静脉血栓栓塞的风险决定因素：一项多位点、基于人群的前瞻性遗传分析

Polymorphism in the β _2-adrenergic receptor and lipoprotein lipase genes as risk determinants for idiopathic venous thromboembolism : A multilocus , population-based , prospective genetic analysis

脂肪肝；高脂血症；肝脂酶；脂蛋白脂肪酶；

Fatty liver Hyperlipidemia Hepatic lipase Lipoprotein lipase ;

脂蛋白代谢的研究&Ⅰ.脂蛋白脂肪酶的分离、提纯及其某些性质的研究

Studies on lipoprotein metabolism ⅰ . isolation , purification and characterization of milk lipoprotein lipase