竞争性拮抗剂

结论该短肽可能作为TGFβ1II型受体的竞争性拮抗剂，抑制或降低了该生长因子对细胞的刺激作用。

CONCLUSION : This polypeptide can be taken as competitive antagonist of TGF β 1 receptor II to antagonize or decrease the stimulation of the growth factor to cells .

α4β2烟碱受体竞争性拮抗剂对注意缺陷多动障碍模型-SHR大鼠非选择性注意、记忆、行为及α4β2烟碱受体表达影响的对照研究

A Control Study of the Effect of α _4 β _2 Nicotinic Receptor Competitive Antagonist on Non-selective Attention , Activity , Memory and Expression of α _4 β _2 Receptor of SHR-an Animal Model of Attention Deficit Hyperactivity Disorder

MNDA受体拮抗剂主要分为二大类，即竞争性拮抗剂和非竞争性拮抗剂，本文综述了竞争性NMDA受体拮抗剂的研究进展。

The antagonists of the NMDA ( N-methyl-D-aspartate ) receptor are divided into two classes , the competitive antagonists and the non-competitive antagonists . In this article , the competitive antagonists of the NMDA receptor are reviewed .

α7nACh受体的竞争性拮抗剂对实验小鼠学习记忆能力的影响

Effects of MLA on Learning and Memory in Mouse

非竞争性拮抗剂可阻止激动剂在特定受体部位产生任何效应。

A noncompetitive antagonist prevents the agonist from producing any effect at a given receptor site .

血小板激活因子受体竞争性拮抗剂海风藤酮能抑制这种作用。

Kadsurenone which is a competitive antagonist of platelet activating factor ( PAF ) receptor could inhibit this effect .

本实验采用脑区埋管给药技术，在C57B1/6小鼠生后发育关键期内，在其左侧大脑听皮层定位、慢性施加NMDA受体NR2B亚单位非竞争性特异拮抗剂MK-801。

In this study , we implanted a pipe on the surface of the left auditory cortex in C57B1 / 6 mice , during their critical period , then chronically administrated the NMDA receptor 2B subunit antagonist MK-801 though the pipe for 10 days .

初期的抗炎症介质治疗研究主要集中在各种促炎因子的抗体、受体拮抗剂和竞争性受体拮抗剂上。

The earlier anti-inflammatory medium treatments had been concentrated to the antibodies , inhibitors , and receptor antagonists of pro-inflammatory factors .

竞争性NMDA受体拮抗剂

The Competitive Antagonists of the NMDA Receptor

有报道非竞争性NMDA受体拮抗剂能使精神分裂症患者和健康志愿者产生精神分裂样症状。

The non-competitive antagonist of NMDA / glutamate receptors has recently been shown to induce schizophrenia-like symptoms in healthy volunteers and in schizophrenic patients .

大量研究证实，非竞争性NMDA受体拮抗剂美金胺（Memantine）可以有效地减少缺氧缺血所导致的脑损伤。

It is reported that Memantine , an uncompetitive NMDA receptor antagonist , can dramatically reduce the degree of brain damage caused by hypoxic ischemia .

目的观察非竞争性NMDA受体拮抗剂地艹卓西平马来酸盐（MK-801）在低剂量时对小鼠焦虑、抑郁以及学习记忆能力的影响。

ObjectiveTo investigate the effect of low dose of N-methyl-D-aspartate ( NMDA ) receptor antagonist MK-801 on the ethology of anxiety , depression , learning and memory in mice .

将动物随机分为正常对照组、Glu-Na致痫组及D-AP-5（非竞争性NMDA受体拮抗剂）+GluNa组。

All rats were divided randomly into three groups : control group ; sodium glutamate group ; and D-AP-5 ( noncompetitive NMDA receptor antagonist ) + GluNa group .

目的研究非竞争性谷氨酸受体拮抗剂硫酸镁在大鼠局灶脑缺血中的作用。

Objective To investigate the effects of magnesium sulfate , a noncompetitive antagonist of glutamate receptor , in focal cerebral ischemic injury of rats .