氨茶碱

氨茶碱对人气道平滑肌细胞增殖抑制及NF-κB表达的影响

Effect of aminophylline on human airway smooth muscle cells apoptosis and the expression of NF - κ B

氨茶碱对哮喘豚鼠肺组织核因子-κB的表达作用

A Study of Aminophylline on the Expression of Nuclear Factor-Kappa B ( NF - κ B ) of the Pulmonary Tissue of Asthmatic Guinea Pigs

同时加入氨茶碱组则ET－1基因表达完全受抑制；

Theophylline entirely inhibited GM CSF induced ET 1 gene expression in the ASMC ;

观察3d，用药前后沙丁胺醇组与氨茶碱组血清钾浓度的变化。

The changes of serum potassium level between two groups before and after the treatment were observed for 3 days .

目的研究氨茶碱对哮喘小鼠气道树突状细胞（DC）的密度和分布的影响。

Objective To investigate the effect of aminophylline-treatment on the distribution and density of airway intraepithelial dendritic cells in murine models .

氨茶碱对K562细胞增殖与凋亡的影响

Effects of Aminophylline on Proliferation and Apoptosis in K562 Cells

结果头孢呋辛钠注射液与氨茶碱注射液配伍后pH值及含量显著下降；

Results The mixture of cefuroxime sodium injection with aminophylline resulted in significant drop in pH and the contents of cefuroxime sodium ;

氨茶碱虽增加Pt，但使膈肌疲劳所需的时间缩短，并延缓疲劳膈肌功能的恢复。

Although aminophylline could increase Pt , it shortened the fatigue inducing time and postponed the recovery .

同时总结COPD患者氨茶碱中毒的临床表现。

The manifestations of aminophylline intoxication on COPD patients were summed up in the same time .

老年COPD患者单剂量口服氨茶碱的药物动力学研究

Study on the Pharmacokinetics of single Oral dose of Aminophylli (?) e in elderly COPD Patient

氨茶碱对哮喘患儿Th亚群体外影响的实验研究

Experimental Study of Effects in Vitro of Aminophylline on Th Subsets from Children with Allergic Bronchial Asthma During Remission Period

结果①氨茶碱或8BrcAMP以时间和浓度依赖的方式降低存活的细胞数；

RESULTS ① Aminophylline or 8 Br cAMP decreased the number of viable cells in time and concentration dependent manner ;

目的：探讨氨茶碱对慢性阻塞性肺病（COPD）极量运动呼吸方式的影响。

? Objective : To investigate influence of aminophylline on breathing patterns in COPD after maximal exercise .

氨茶碱对COPD不同年龄患者生活质量及肺功能的影响

Effect of oral aminophylline on qulity of life and pulmonary function in different age groups of COPD patients

TNFα对人外周血CD（15）~+细胞表面粘附分子的诱生及氨茶碱的作用

The inductive effect of TNF α on cellular adhesion molecules in human peripheral CD 15 + cells and the effects of aminophylline on it

哮喘豚鼠肺组织SOD、MDA、IL-2及IL-6含量的变化及氨茶碱的影响

Alteration of SOD , MDA , IL-2 and IL-6 Level in lung Tissues of Asthmatic Guinea Pigs and the Effects of Aminophylline

氨茶碱对哮喘患儿TH2/TH1细胞因子的调节作用

Modulatory effect of aminophylline on T_H2 / T_H1 cytokines of asthmatic children

氨茶碱、环磷酸腺苷葡甲胺（MCA）对兔膈肌功能的影响

Effects of aminophylline and meglumine cyclic adenylate ( mca ) on diaphragmatic function in rabbits

免疫抑制大鼠腹腔感染致MODS发生机制及氨茶碱治疗的实验研究

Experimental Study on the Mechanisms and the Therapeutic Effect of Aminophylline for MODS Induced by Peritonitis in Rats with Immunosuppression

结论复苏早期合用腺苷受体拮抗剂氨茶碱可提高复苏成功率，改善心脏功能，降低血浆NO和心肌组织ET-1水平。

Conclusion Aminophylline as adenosine receptor antagonist used early in CPR would increase the successful rate of resuscitation and improve cardiac function .

结论氨茶碱可通过抑制eotaxin的表达减轻哮喘炎症。

Conclusion Aminophylline can ameliorate asthmatic inflammation by inhibiting eotaxin expression .

氨茶碱抑制哮喘缓解期患儿外周血单个核细胞体外合成IL-4和IL-10的观察

Effect of aminophylline on IL-4 and IL-10 released by peripheral blood mononuclear cells ( PBMC ) in asthmatic children during remission period

建立了复方甲氧那明胶囊中盐酸甲氧那明、氨茶碱、那可汀、马来酸氯苯那敏含量的RP-HPLC测定法。

A RP HPLC method for simultaneous determination of methoxyphenamine hydrochloride , aminophylline , narcotine and chlorphenamine maleate in compound methoxyphenamine capsules was established .

但氨茶碱组血浆中cAMP浓度不论第7d、28d均高于模型组。

The level of cAMP in plasma was higher than the model group whether on the 7 th or 28 th d.

结果表明，氨茶碱膜剂以零级动力学经皮渗透，0～12h累积渗透量44.7%，渗透速率16.58μg/cm2·h。

The permeation of aminophylline in the films through the mice skin followed zero-order kinetics . The permeation rate was 16.58 μ g / cm 2 · h .

CPB结束后1小时和8小时，对照组RI较基础值和氨茶碱组明显增高（P＜0.05）；

RI at 1 and 8h after CPB in control group was higher than the baseline value before CPB and that in the aminophylline group ( PO . 05 ) .

结论氨茶碱可能通过抑制肺组织TRAIL的表达来抑制TRAIL的促炎作用，同时还可以通过促进哮喘大鼠气道的T淋巴细胞凋亡发挥抗炎作用。

Conclusion Aminophyline could inhibit the inflammation of asthmatic airway by reducing the expression of TRAIL in rat lung and promoting the apoptosis of T-lymphocytes in asthmatic rat airway .

结论：COPD患者极量运动后气体交换参数恢复半衰期较正常人明显延长，常规剂量氨茶碱对此无明显影响。

Conclusions : Recovery half life of gas exchange in COPD is significantly longer than in the normal individuals and is not influenced by aminophylline in common dosage .

氨茶碱对TNF-α诱导下大鼠气道平滑肌细胞中RANTES的影响

Effects of Theophylline on the Expression of RANTES in the Airway Smooth Muscle Cells of Rats Induced by TNF-alpha

氨茶碱调节大鼠支气管平滑肌L型钙通道的活动性

Aminophylline modulates voltage sensitivity of calcium channels in bronchial smooth muscle of rats