氨基糖苷类

对MDR-TB的治疗主要依靠二线抗结核药物，主要有氨基糖苷类、多肽类、氟喹诺酮类等。

The treatment of MDR-TB largely relies on the second line anti-TB drugs , including aminoglycosides , polypeptides , thioamides and fluoroquinolones .

肠杆菌科细菌对头孢吡肟、酶抑制剂复合制剂、氨基糖苷类和喹诺酮类敏感率较高，对碳青霉烯类保持高度敏感。

Enterobacteriaceae species were sensitive to cefepime , the enzyme inhibitor complex , aminoglycosides and quinolones , and remained high sensitive to carbapenems .

常规的理化分析得出B组分为氨基糖苷类化合物。

B was identified as aminoglycoside compound by general analysis method .

母系遗传氨基糖苷类抗生素致聋家系的线粒体DNA突变分析

Mutation Analysis for Mitochondrial DNA in a Chinese Pedigree with Maternally Inherited Aminoglycoside Antibiotic-Induced Deafness

用PCR法检测氨基糖苷类药物修饰酶基因。

The PCR method were performed to determine the genotypes of aminoglycoside modifying enzymes .

鲍曼不动杆菌TEM基因及氨基糖苷类修饰酶基因初步研究

Study on the genes for TEM and aminoglycoside-modifying enzymes

采用聚合酶链反应（PCR）扩增4种氨基糖苷类药物修饰酶基因，并使用DNA测序加以证实。

Four aminoglycoside-modifying enzyme genes were amplified by polymerase chain reaction ( PCR ) and verified by DNA sequencer .

用离子交换柱分离氨基糖苷类抗生素妥布霉素、新霉素B和西梭霉素，用脉冲积分安培电化学检测器进行检测。

A new method was developed for detection of aminoglycoside antibiotics of tobramycin , neomycin and sisomycin by ion-exchange column with pulsed integrated amperometric detection .

结果1994～1998年氨基糖苷类、硫霉素、多粘菌素B、克拉霉素、麦迪霉素均无耐药菌；

RESULTS All of campylobacters were isolated from 1994 to 1998 . No strain was resistant to aminoglycosides , imipenem , polymycin B , clarithromycin , josamycin , midecamycin .

新疆地区鲍氏不动杆菌氨基糖苷类修饰酶与16SRRNA甲基化酶基因研究

Aminoglycoside-modifying Enzyme and 16S rRNA Methylase Gene Expressions in Acinetobacter baumannii

产ESBLs大肠埃希菌氨基糖苷类修饰酶基因的研究

Genotyping of Aminoglycoside-modifying Enzymes in ESBLs-producing Escherichia coli

方法应用PCR和DNA序列分析技术，对一个有明确氨基糖苷类抗生素应用史的母系遗传耳聋家系共18人（包括聋人和听力正常者）的线粒体DNA进行研究。

Methods The mutation of mitochondrial DNA from all 18 family members of a chinese pedigree with maternally inherited aminoglycoside antibiotic-induced deafness was detected by PCR and DNA sequencing .

紫外和红外谱图分析表明：组分a、c、d为氨基糖苷类物质，组分Be则更接近于核苷类物质的特点。

The analysis of ultraviolet spectrum and infrared spectrum indicated that components a , c , and d are aminoglycoside substances , and component Be is more identical to nucleosides substance in characteristics .

肺炎克雷伯菌（ESBLs）氨基糖苷类修饰酶基因的研究

Study on aminoglycosides-modifying enzymes gene of extended-spectrum beta-lactamases ( ESBLs ) - producing Klebsiella pneumoniae

多药耐药铜绿假单胞菌氨基糖苷类修饰酶和16SRRNA甲基化酶基因分析

Analysis on gene types of aminoglycoside modifying enzyme and 16S rRNA methylases in multidrug-resistant Pseudomonas aeruginosa

结果表明：BSA能替代化学表面活性剂用于氨基糖苷类抗生素的泡沫分离。

The results showed that BSA can be used in the foam separation of aminoglycosides antibiotics instead of chem-surfactants .

细菌对氨基糖苷类药物耐药基因四重PCR检测试剂盒研制与应用四种虫媒病毒多重RT-PCR方法的初步建立

Study on a Multi-PCR Amplification Kit of Detection Bacteria Aminoglycoside Resistance Genes and Its Application ; The Initial Establishment of Multiplex RT-PCR for Detection Four Kinds of Arboviruses

以期为基于MSW理论的新的临床用药策略提供科学依据，遏制铜绿假单胞菌对氨基糖苷类药物的耐药。

So as to provide scientific evidences for the new clinical medication based on MSW theory , to restrain the resistance of .

MRSA和MSSA氨基糖苷类药物耐药性和耐药基因检测

Detection of Aminoglycoside-resistance and the Presence of Resistant Genes between MRSA and MSSA

大肠埃希菌氨基糖苷类耐药株aac（3）-Ⅱ基因保守区分析

Conserved Region Analysis of aac ( 3 ) - ⅱ Gene From E.coli Aminoglycoside Resistance Strain

armA和rmtB可以导致细菌对氨基糖苷类抗生素的高水平耐药。

ArmA and rmtB can induce high-level resistance to aminoglycosides .

氨基糖苷类药物高水平耐药16SRRNA甲基化酶基因在动物源大肠杆菌中的检测

Detection of 16S rRNA Methylase Genes Which Mediated High Level Resistance to Aminoglycosides among Escherichia coli Strains Isolated from Animals

目的：探讨甲氧苄啶（TMP）与3种氨基糖苷类抗生素（庆大霉素、阿米卡星、妥布霉素）的联合抗生素后效应（PAE）。

Objective : To explore the post-antibiotic effects ( PAE ) of trimethoprim ( TMP ) combined with aminoglycosides .

目的：1.探讨鲍曼不动杆菌（Acinetobacterbaumannii，AB）对氨基糖苷类抗生素的耐药性及其耐药机制。

Objective : 1 . Explore on the drug resistance and its mechanism of Acinetobacter baumannii ( AB ) to aminoglycoside antibiotics . 2 .

甲氧西林敏感表皮葡萄球菌（MSSE）对头孢菌素类、氨基糖苷类、喹诺酮类依然保持较低的耐药率。

MSSE still kept low resistance to cephalosporins , aminoglycosides and quinolones .

新霉素（neomycin，NEO）是一种氨基糖苷类抗生素（aminoglycosides），因其具有高效、广谱的抗菌作用，广泛应用于医药和兽药领域。

Neomycin is an aminoglycoside antibiotic which was widely used in veterinary medicine because of its broad-spectrum antibacterial effect .

tenebrariusH6产生多种氨基糖苷类抗生素，主要有阿泊拉霉素、妥布霉素及卡那霉素B。

Streptomyces tenebrarius H_6 produces a complex of aminoglycoside antibiotics , such as apramycin , tobramycin and kanamycin B etc.

临床治疗MP感染主要选择抑制或影响蛋白质和核酸合成的药物，如大环内酯类、四环素类、氨基糖苷类、喹诺酮类。

Antibiotics which can affect the protein and nucleic acid synthesis , including macrolide , quinolone , aminoglycosides , and tetracycline , were effective for the therapy for MP infection .

链霉菌的氨基糖苷类抗生素3′&磷酸化酶APH（3′）抑制剂性质初探

Primary Studies on the Property of Aminoglycoside Antibiotic 3 ' - Phosphotransferase Inhibitor from Streptomyces

结果：PCR结果显示TEM、GES型β-内酰胺酶基因，aac（6′）-Ⅰ、ant（2〃）-Ⅰ氨基糖苷类修饰酶基因扩增阳性。

Results : β - lactams genes of TEM and GES , aminoglycoside genes of aac ( 6 ' ) - ⅰ and ant ( 2 ″) - ⅰ were positive .