梭形细胞

结果：培养的MSCs为形态学均一的梭形细胞，有时可见细胞融合。

RESULTS : The isolated subculturing MSCs displayed a fusiform cell like morphology .

Nissl染色结果显示人脑纹状体壳核内侧缘靠近苍白球外节边缘，可见有一条明显的梭形细胞带。

In the Nissl stained section , there is a distinct fusiform cell zone between the putamen and globus pallidus of the human striatum .

梭形细胞肉瘤B（22）（N-甲不敏感瘤），60.9%；

Spindle cell carcinoma B_ ( 22 )( NF-resistant ), 60.9 % .

梭形细胞变异型弥漫性大B细胞淋巴瘤1例报道及文献复习

Diffuse Large B Cell Lymphoma with Spindle Cell Variant : Report of 1 Case and Review of the Literature

目的探讨梭形细胞变异型弥漫性大B细胞淋巴瘤的临床病理特征、病变性质及鉴别诊断要点。

Objective : ? To investigate the clinical-pathological features , and differential diagnosis of diffuse large B cell lymphoma with spindle cell variant .

方法对1例梭形细胞变异型弥漫性大B细胞淋巴瘤的组织形态特征、免疫组化表型，结合临床预后进行分析。

Methods : ? A case of diffuse large B cell lymphoma with spindle cell variant was analyzed for histomorphology , immunohistochemical features and clinical prognosis .

混合细胞型、上皮样细胞型中染色体改变高于梭形细胞型的染色体改变（P0.05）。

( P0.05 ) Monosomy of mixed cell type and epithelioid cell type was more than that of spindle cell type .

而梭形细胞则Keratin、EMA和Vim阳性。

Keratin , EMA and Vim were identified in spindle cells .

培养14d时，梭形细胞融合成内皮细胞单层。

After 14 days ' culture , endothelial cells monolayer was formed .

培养72h后对照组细胞为贴壁的梭形细胞，细胞排列紧密。

After 72 h cultured , The control group cells were adherent spindle , tightly packed .

葡萄膜恶性黑色素瘤AgNORs面积则按梭形细胞型、混合细胞型及上皮样细胞型顺序增加（P＜0.05）。

The AgNORs ares in uveal malignant melanomas increased gradually in order of spindle-cell type , mixed-cell type and epithelial-cell type ( P < 0.05 ) .

梭形细胞型胸腺瘤Bcl2蛋白均为阳性。

Bcl 2 expression was highly associated with the spindle thymomas .

结果：单个核细胞培养3d后可见大量的附着细胞和少量梭形细胞，梭形细胞数量在第7天时达到高峰。

Results After the mononuclear cells were cultured for 3 days , a large amount of attached cells and some spindle shaped cells were observed . The number of spindle shaped cells increased until 7th day .

方法在光镜观察胃肠道非上皮性梭形细胞肿瘤的基础上，运用免疫组织化学方法检测vimentin、CD34、actin和S－100。

Method In addition to light microscopic observations immunohistochemical assays of vimentin , CD34 , actin and S & 100 were used .

CD34和FⅧRAg在血管瘤样型表达强，梭形细胞型表达弱（P0.01）。

CD34 and F ⅷ RAg expression was significantly different among three types ( P 0.01 ), strong in the angiomatous type , weak in the spindle cell type .

网状区的梭形细胞VEGF阳性表达。

Some spindle cells in ramified region of pterygium were stained brown by VEGF . The GAPDH gene expression was positive in all specimens . This expression pattern was further conformed by RT-PCR .

常规方法培养中窦房结梭形细胞所占比例为45%，而差速贴壁技术结合BrdU处理的纯化培养中梭形细胞达68%左右（P<0.01）。

The proportion of spindle cells increased from 45 % among the cells cultured with routine method to 68 % among cultured with differential attachment and BrdU treated method .

c-metmRNA表达与c-met蛋白相同，p53mRNA表达在血管瘤样型高于梭形细胞型。

The expression of c-met mRNA in three types was similar to the c-met protein , but the expression of p53 mRNA was stronger in angiomatous type than that in spindle all type .

采集对照组循环外周血进行内皮祖细胞（EPCs）的分离培养，7d后搜集贴壁的梭形细胞，采用改良的Boyden小室检测VEGF对于EPCs迁移功能的影响。

After 7 days culture , attached cells were collected . The effect of VEGF on the migration of endothelial progenitor cells ( EPCs ) were assayed with modified Boyden chamber assay .

结果：培养早期（1～3代）MCC以多角形为主，5～6代后梭形细胞增多；

Results : The majority of MCCs in earlier passages ( 1 ~ 3 passage ) were polygonal , while more fusiform and spindle shaped cells were found after 5 ~ 6 passages .

并可见NADPH－d阳性的梭形细胞呈背腹方向排列，突起由细胞背腹方向伸出很长距离。

Numerous NADPH-d positive fusiform cells were ranked dorsoventrally between the putamen and globus pallidus , and the dendrites of NADPH-d positive cells were extended long distance from the cell body dorsally and ventrally .

利用裸鼠建立人前列腺梭形细胞瘤细胞系PC-98106的研究

Study on establishment of a human prostate tumor cell line PC-98106 by nude mice

结果39例胃肠及胃肠外间质瘤主要由梭形细胞和上皮样细胞构成，其中38例CD117阳性，32例CD34阳性。

Results The GIST and parenteral interstitialoma in the 39 cases were mainly composed of spindle cells and epithelioid cells in which CD117 was positive in 38 cases and CD34 was positive in 32 cases .

具有罕见轻微临床表现的梭形细胞黑素瘤患者的XPA基因新突变

A novel mutation in the XPA gene associated with unusually mild clinical features in a patient who developed a spindle cell melanoma

结果滑膜肉瘤一般具有双向分化特点，由上皮样细胞和梭形细胞组成，免疫组化可表达Vimentin、广谱CK、低分子量CK、bcl-2、S-100、CD99等。

Results Synovial sarcoma possessed bi-phases differentiation characters usually , composed of epithelioid cells and spindle cells , which expressed Vimentin , CK-pan , low molecular CK , bcl-2 , S-100 protein and CD99.Conclusion Synovial sarcoma has diverse histological features ;

结论原发性肾脏滑膜肉瘤罕见，需要与肾脏其他一些梭形细胞肿瘤相鉴别，分子遗传学检测SYT-SSX融合mRNA有助于其诊断和鉴别诊断。

Conclusions Primary synovial sarcoma of the kidney is rare . It should be differentiated from the other spindle cell tumors of the kidney . SYT-SSX mRNA detection by molecular genetics can be useful in its diagnosis and differential diagnosis .

其组织病理特征：真皮层表达CD34的梭形细胞增殖并向下扩展到皮下脂肪组织，间质黏蛋白和弹性纤维轻度增加并伴弹性组织离解；

The skin-biopsy specimen shows a proliferation of CD34-expressing dermal fibrocytic spindle-cells which extend into subcutaneous fat , a slight increase of interstitial mucin and elongated elastic fibers with elastolysis . A colloidal iron stain reveals the deposition of a small amount of mucin in the superficial dermis .

结果显示：将bFGF与BDNF的组合分别加到10%和5%血清的OE培养基（OEM）中，增加了双极细胞的数量和比例，刺激了双极细胞突起的发育，减少了大细胞和梭形细胞。

The results showed that the combination of bFGF and BDNF added to 10 % and 5 % serum OE medium increased the bipolar cell number and percentage , stimulated the process outgrowth of bipolar cells , and decreased the numbers of giant cells and fusiform cells .

4wk时可见大面积出血性坏死，汇管区明显增宽，窦壁细胞增生显著，有大量的长梭形细胞附着，窦壁增厚，肝窦甚至扭曲；

On 4 wk , the lesion consisted of a large areas of hemorrhagic necrosis and enlarged portal tracts , sinusoid wall cells intensely proliferated , and attached with numerous long fusiform cells ;

胃肠梭形细胞肿瘤49例临床病理分析

Gastrointestinal spindle cell tumors : a clinicopathologic analysis of 49 cases