成熟卵泡

成熟卵泡数明显多于自然周期组（P＜0.01）；

The number of mature follicle ( D ≥ 18mm ) in CC cycle was much more as compared with natural cycle ( P0.01 ) .

PCOS患者双侧卵巢虽有大量窦卵泡，但是不能周期性形成成熟卵泡，目前虽有一些的病理研究，但其病理机制尚不十分清楚。

Both ovaries of PCOS patients contain a large number of antral follicle , but cannot form mature follicle .

3次免疫后大鼠成熟卵泡发育数比2次免疫后显著提高（35.2±2.73vs31.0±0.92，P0.05）。

The mature follicles after three times immunizations were remarkably more than that after twice immunizations ( 35.2 ± 2.73 Vs.31.0 ± 0.92 , P0.05 ) .

100μg剂量组2次和3次免疫的成熟卵泡发育数分别比对照组多6.9和7.5个（P<0.05）。

There were 6.9 and 7.5 more mature follicles in 100 μ g group after twice and three times immunizations of pCIS than that in the control ( P < 0.05 ) .

PCOS患者因卵泡发育停滞，无成熟卵泡，因此促使卵泡发育、成熟、诱发排卵是治疗PCOS不孕症的关键环节。

PCOS patients with follicular development stagnation , and no mature follicles , so the key treatment to PCOS patients is to promoting follicles development , and inducing ovulation .

目的通过自体血清和人成熟卵泡液来源的两种不同IVM培养系统对PCOS不孕患者行IVM治疗的病例对照研究，比较两者的临床结局。

Objective To compare the clinical outcome of study on PCOS women treated by IVM of oocytes maturated in two different IVM media , which include patient serum or human follicular fluid .

目的探讨培养液中添加人成熟卵泡液（HFF）、表皮生长因子（EGF）对人未成熟卵母细胞体外成熟（IVM）、体外受精（IVF）及其胚胎发育的影响。

Objective The experiment was carried out to study the effects of EGF and HFF in culture medium on in vitro maturation . fertilization and embryo developmental competence of human immatured oocytes . Mothods Human immatured oocytes came from patients with PCOS who were received IVM treatment .

结果：胎儿卵巢经组织培养后，较成熟卵泡比例增加，P0.005；加胎儿胰腺条件培养液组与未加胎儿胰腺条件培养液组相比，较成熟卵泡比例增加更为明显（P0.005）。

Results : The constituent ratio of more mature follicles increased after being cultured in vitro , and the ones increased more significantly after being cultured in conditioned culture medium of human fetal pancrease comparing with the group without conditioned culture medium ( P 0.005 ) .

在原始卵泡、初级卵泡、次级卵泡及成熟卵泡的颗粒细胞中都有mPGES免疫染色，其中原始卵泡中最强，初级卵泡、次级卵泡和成熟卵泡中较强。

There was detectable mPGES immunostaining in the granulosa cells of the different follicles . The strongest mPGES immunostaining was seen in the primordial follicles , while a strong level of the immunostaining was also observed in the primary follicles , the secondary follicles , and mature follicles .

探讨以人成熟卵泡液作为体外成熟培养液培养牛卵母细胞的可能性。

Effect of hyaluronic acid on in vitro maturation of bovine oocytes development of early embryos ;

米非司酮对小鼠成熟卵泡、囊胚发育及超微结构的影响

Effects of Mifepristone ( MP ) on the Development and Ultrastructure of Mouse Mature Follicle and Blastocysts

在三级卵泡和成熟卵泡的卵泡液中也有IFN-γ的表达；

The IFN - γ expression exists in the follicular fluid of late tertiary follicle and mature follicle , too .

20日龄时卵巢总数中有二分之一出现成熟卵泡，最大直径4.5mm。

At the 20th day , a half of the total ovaries tested had mature follicles with maximum diameter of 4.5 mm .

促排多胎素具有刺激成熟卵泡排卵，促进发情，调节发情周期，提高母畜受胎率的功效。

LHRH injection stimulates the ovulation and estrous and regulated the estrous cycle to in - crease the conception rate of cows .

牛蛙卵细胞在生长发育过程中可以分为卵原细胞期、初级卵泡期、生长卵泡期和成熟卵泡期。

The entire course of oogenesis can be divided into four stages , i.e.oogonium , primary follicles , growing follicles and mature follicles .

妊娠率，外加成熟卵泡数，取消的周期数，必须的促性腺激素的总量。

Pregnancy rates ( PR ) . In addition , number of mature follicles , cycle cancellations , amount of required gonadotropins were documented .

计数成熟卵泡、生长卵泡的数目、卵巢颗粒细胞层面积、黄体数量。

And the numbers of mature follicles , growing follicles and corpora lutea were calculated , and also the surface area of granule cells of ovaries was calculated .

而空白对照组则初级卵泡量少，可见次级卵泡，成熟卵泡很少，结缔组织增生，且卵巢血管少，血管的密度也小，形状不规则。

The control group were less primary follicle , that secondary follicles and mature follicles little connective tissue hyperplasia and ovarian vascular less vascular density of small , irregular in shape .

目的通过超声观察药物诱发排卵卵泡发育情况、卵泡大小与妊娠率、妊娠结局的关系，旨在探索促排卵正常成熟卵泡大小范围值及最易妊娠卵泡径线范围值。

Objective To study the relationship between ovarian follicle size induced by drug ovulation facilitation and pregnant rate and pregnant outcome , and to find the common and easy-pregnant follicle size value in the ovary treated with drug ovulation facilitation .

结果：1.普通HE染色结果表明：用药组大鼠卵巢皮质内有较多的原始卵泡，与其对照组比较，典型的生长卵泡和成熟卵泡明显减少。

Results : 1 . The results of HE staining showed that : compared with control group , there were more primordial follicles and less typical growing follicles and mature follicles in cortex of rat ovary in the drug-given group .

光镜下，染毒组小鼠卵巢中的原始卵泡、闭锁卵泡数目较多，而初级卵泡、次级卵泡和成熟卵泡数目明显减少。

Observing minute structure of ovary by the light microscope , compare to the control group , primitive follicles and atresic follicles of the lead treatment groups had increased , and the primary follicles , secondary follicles and mature follicles were significant decreased .

颗粒细胞对卵母细胞成熟、卵泡发育有至关重要的作用。

Granulosa cells are crucial to oocyte maturation and follicular development .

PMSG对性成熟前小鼠卵泡发育的影响及牛卵母细胞体外培养技术研究

Effect of PMSG on Prepubertal Mouse Follicular Development of Ovary and in Vitro Maturation of Bovine Oocytes

结论：PCOS患者窦状卵泡自身卵母细胞结构异常导致卵泡未能发育成熟为优势卵泡，是顽固性PCOS患者不孕的主要因素之一。

Conclusions : The abnormality in oocyte itself cause that the antral follicle fail to develop dominant follicle is one of the main reasons for some PCOS women with refractory infertility .

病理切片发现高、中剂量组小鼠成熟及闭锁卵泡有轻度变性；

High and medial dose groups ' mature follicle and atretic follicle have low-grade degeneration .

将体外成熟的小腔卵泡卵母细胞与体外获能精子进行受精，其受精率为35.7%（51／143）。

SAF oocytes maturated were fertilization in vitro with capacited sperm and in vitro fertilization rate is 35.7 % ( 51 / 143 ) .

尽管哺乳动物卵巢含有的卵泡甚多，但其一生能成熟排卵的卵泡数很少，绝大多数（约有99.9%）的卵泡在腔前卵泡阶段闭锁、退化，这无疑是极大的资源浪费。

Although many follicles is in the mammalian ovary , few can develop the ovulatory follicles in life and the vast majority ( about 99.9 % ) are atresia or degradation in preantral phase among them . This is a great waste .

本研究以水牛卵母细胞和卵泡液为实验材料，通过双向电泳、液相色谱和质谱技术分析卵母细胞体外成熟过程中以及卵泡在发育过程中蛋白质表达的差异性。

In this study , two-dimensional electrophoresis , liquid chromatography , and mass spectrometry were used to analysis the different protein expression in buffalo oocytes during in vitro maturation and during development .

在性成熟前小鼠，卵泡细胞能够分泌少量雌激素；性成熟后，在下丘脑-垂体-性腺轴的调控下，雌激素分泌量增加，加速卵泡发育至性成熟。

In mice , follicle cells secreted a small amount of estrogen during prepuberty , and estrogen secretion increased sharply under the control of hypothalamus-pituitary-gonadal axis to accelerate follicular development up to sex maturation .