可兴奋细胞
- 名excitable cell;excitation cell
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目的小电导钙激活的钾通道(SK3)介导了动作电位后的后超极化电位的产生,在调节可兴奋细胞的膜电位中起关键作用。
Objective Small conductance calcium-activated potassium channels ( SK3 ) have been thought to play an important role in excitable cells because they mediate the afterhyperpolarization following action potentials .
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钙和电压激活的大电导钾离子通道(Maxik通道,又名BK通道)广泛地存在于可兴奋细胞,特别是神经系统中,具有调节胞内钙浓度和膜电位等重要生理功能。
Calcium - and voltage - activated large conduction potassium channel ( Maxik channel , also termed BK channel ) extensively exists in excitable cells , especially in neural system . BK channel plays a significant physiological role in mediating the concentration of intracellular calcium ions and the membrane potential .
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动作电位,对于可兴奋细胞,包括神经元和一些内分泌细胞,是一种非常重要的生理信号。
Action potential ( AP ) is a very important physiological signal in excitable cells including neurons and neuroendocrine cells .
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于是我们实验室首次提出可兴奋细胞的反应性随放电动力学状态而改变的动态反应规律假说。
Based on above results we postulated the hypothesis that responsiveness of excitable cells changed following its firing dynamic states .
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离子通道的活动是可兴奋细胞传递信息的基础,膜片钳技术的发明导致了生命科学的一场革命。
Action of ion channel on membrane is the key events of messenger transduction for excitable cells , which can be detected by the patch clamp technique .
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蝎长链神经毒素由60~76个残基组成,含4对二硫键,主要作用于可兴奋细胞的Na+通道。
Long-chain scorpion neurotoxins consist of 60 ~ 76 amino acids crosslinked by 4 disulfide bridges , most of which can act on sodium channels of excitable cells .
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以钾通道为例,它参与可兴奋细胞动作电位的复极化。
A notable example of ion channels that plays an essential role in physiology is potassium channels that are involved in the repolarization of action potentials in excitable cells .
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对组织细胞进行刺激可以改变可兴奋细胞对Na~+(或Ca~(2+))通透性,从而产生动作电位,使其内部的Na~+、K~+离子通道发生变化引起内部环境的改变,最终改变细胞的状态。
The organic cells that have potential excitation can change the penetrability of Na ~ + ( or K ~ + ) if they receive stimulation from external , then Action potential occurs .
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可兴奋细胞,如神经细胞、肌肉细胞和腺体细胞等,均能产生动作电位响应外界刺激(如光、电、药物等)。
Electrogenic cells , such as neural tissues , cardiac muscle cells and adenoid cells , could response the exoteric stimulations ( such as light , electricity and medicine ) by generating the action potentials .
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味觉受体细胞具有神经细胞特性,也属于可兴奋性细胞,将其培养在LAPS芯片表面,味觉细胞电位的改变即可通过检测LAPS的光生电流得以测量。
Taste cells are cultured on the LAPS chip for several days and then the change of extracellular signals can be detected by measuring the change of LAPS photocurrent . The phenotype of those cells was NKH1 + CD16 - .
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电压门控钠通道(VGSC)在神经元及大多可兴奋性细胞动作电位的形成和传播过程中扮演着极为重要的角色。
Voltage gated sodium channels ( VGSC ) are responsible for the rising phase of the action potential in the membrane of neurons and most electrically excitable cells .
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混沌放电的可兴奋性细胞对外界刺激反应敏感的动力学机制
The dynamical mechanisms for the sensitive response of excitable cells with chaotic firing to external stimulation
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嗜铬细胞作为一种典型的可兴奋性细胞,在调节哺乳动物神经内分泌的过程中起着重要作用,它上面包含有多种调节细胞兴奋性的离子通道。
As a typical kind of electrical excitable cells , chromaffin cells play an important role in neural incretion . There are many kinds of ion channels in chromaffin cells which can regulate the excitability .
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非可兴奋性内皮细胞α7受体与血管新生
α 7 nicotinic receptors in non-excitable endothelium and angiogenesis
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双孔钾离子通道是一个膜蛋白家族,广泛分布于可兴奋和不可兴奋细胞中。
Two-pore ( 2P ) - domain potassium channels are a diverse family of membrane proteins present in both excitable and non-excitable cells .
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这些活性多肽可选择性地特异结合并调控可兴奋细胞膜上的离子通道。它作为十分有价值的探针被广泛应用于相关靶离子通道分子调控机理的研究。
Mainly neurotoxic proteins or peptides can interact specifically with various ionic channels in excitable membranes , so they have been used as valuable probes for the elucidation of structure and function of ion channels .