切除修复

DNA切除修复标志物在肺癌、食管癌组织中的表达

Study on the Expression of DNA Excision Repair Biomarkers In Lung And Esophageal Cancer Tissues

切除修复交叉互补酶1在非小细胞肺癌中的表达及其对术后铂类辅助化疗的影响

Expression of excision repair cross-complementation group 1 in non-small-cell lung cancer and its contribution to Cisplatin-based adjuvant chemotherapy

DNA切除修复酶的表达及与肺癌预后的关系

Expression of DNA excision repair enzymes and lung cancer prognosis

结果发现，这5例病人淋巴细胞中的DNA切除修复功能都有不同程度的缺陷。

The result shows that DNA excision repair capacity is defective in these patients .

急性脑梗死发生后，机体启动以碱基切除修复为主的DNA损伤修复机制。

Base-excision repair , the main DNA repair mechanism is initiated after acute cerebral ischemia .

RNA干扰技术抑制切除修复交叉互补基因1对卵巢上皮性癌细胞顺铂敏感性的影响

Enhanced cisplatin cytotoxicity by RNA interfering the excision repair cross-complementing 1 gene in ovarian cancer cell lines

目的以人卵巢转移瘤及癌旁正常组织为研究对象，探求DNA切除修复基因ERCC2表达与人卵巢转移瘤发生、预后的关系。

Objective To investigate the expression of tumor 's ERCC 2 in human ovarian metastatic tumor and its relationship with the incidence and prognosis .

诱导分化的人食管癌细胞DNA聚合酶β和碱基切除修复功能的改变

Expression of DNA polymerase β induced by all-trans retinoic acid and dimethyl sulfoxide and change of the base excision repair in human esophageal cancer cells

针灸对CTX小鼠骨髓细胞DNA切除修复相关蛋白的调节

Effects of acupuncture and moxibustion on DNA excision repair-related proteins of bone marrow cell in Cyclophosphamide-induced mice

DNA聚合酶β（polymeraseβ，polβ）主要是单个碱基切除修复中的关键酶之一。

DNA polymerase B ( pol B ) is the key enzyme for single base excision repair .

它在DNA的碱基切除修复、对转录因子的氧化还原调控和活性氧簇的调控等多个重要的生物学过程中发挥着主要的作用。

APE1 / Ref-1 plays a central role in DNA base excision repair , redox-dependeent regulation of specific transcriptional factors and production control of reactive oxygen species .

目前已鉴定的这一基因家族的多数成员均参与几种重要的DNA修复途径，包括碱基切除修复、同源重组修复和非同源末端重接。

Most members of the XRCC genes family participated in several DNA repair pathways , including base excision repair , homologous recombination repair and non-homologous end joining .

针对不同的DNA损伤。细胞内有许多不同的修复方式对其进行修复，包括碱基切除修复、核苷酸切除修复、错配修复、同源重组修复等。

There are many DNA repair pathways to different DNA lesions , including base excision repair , nucleotide excision repair , mismatch repair and homologous recombination repair .

在DNA损伤的众多修复途径中，核苷酸切除修复（NER）途径能广谱识别大多数严重损伤造成的DNA螺旋扭曲，是DNA损伤的主要修复系统，也是机体抵抗致癌效应的主要防御机制。

Nucleotide excision repair ( NER ) can recognize a broad spectrum of helix-distorting lesions and is a major repair system of DNA damage .

已知细胞中DNA氧化性损伤主要通过碱基切除修复（BER）来完成，许多修复酶参与了这一修复过程。

The DNA oxidative damage is believed that it is repaired mainly by the base excision repair ( BER ) mechanism with many repairing enzymes .

在恢复阶段的早期5天内，DNA损伤持续的增加，这应该是由于对DNA损伤的修复造成的，例如，碱基切除修复或者核苷酸切除修复。

At the first five days of the recovery period , the increased DNA damage may be due to the repair of DNA damage , such as base or nucleotide excision repair .

人类细胞内存在着完整的修复系统，其中包括碱基切除修复系统（baseexcisionrepair，BER）和同源重组修复系统（HomologousRecombination，HR）。

There are complete repair system in normal cells , including base excision repair system ( BER ) and homologous recombination repair system ( HR ) .

碱基切除修复基因SNP的鉴定及其与食管癌的关联研究

Identification of Genetic Variants in Base Excision Repair Pathway and Their Associations with Risk of Esophageal Squamous Cell Carcinoma

其主要功能是碱基切除修复（baseexcisionrepair，BER），在单核苷酸缺口的填补中起重要作用。

The primary function of which is the base excision repair ( Base excision repair , BER ) process , playing an important part in filling the single nucleotide gap .

结果表明，该多糖能显著增强辐射引起DNA损伤的切除修复活性和程序外DNA合成（UDS）。

The results showed that the presence of the polysaccharide enhanced significantly both UV damaged DNA incision activity and UDS in the root-tip cells of Vicia faba irradiated with gamma-rays .

背景与目的：XPC基因参与核苷酸切除修复，该基因存在单核苷酸多态性（SNP）位点，并可能通过SNP位点碱基的改变影响其修复能力及疾病易感性。

BACKGROUND & OBJECTIVE : Xeroderma pigmentosum group C ( XPC ) gene is involved in nucleotide excision repair ( NER ) .

狗及大鼠精巢细胞的PNA切除修复能力与其核内非组蛋白含量的关系

The relationship between the DNA excision repair ability and the content of non-histone nuclear proteins of male germ cells of dog and rat

碱基切除修复对结核分枝杆菌等胞内致病菌尤其重要。fpg是碱基切除修复的关键酶。

This is particularly important for Mycobacterium tuberculosis and other intracellular pathogens , fpg is the key enzyme in base excision repair .

2例胰头癌因与下腔静脉（IVC）前壁粘紧不能分开则合并下腔静脉前壁部分切除修复。

Partial inferior vena cava ( IVC ) reconstruction was done in 2 cases as the tumor adhered to the anterior wall of the IVC .

碱基切除修复（BER），是清除细胞内DNA损伤的主要途径。碱基切除修复基因SNP的鉴定及其与食管癌的关联研究

Genes encoding enzymes involved in DNA replication are potential targets for mutations leading to cancer . Identification of Genetic Variants in Base Excision Repair Pathway and Their Associations with Risk of Esophageal Squamous Cell Carcinoma

目的探讨RNA干扰技术抑制切除修复交叉互补基因（ERCC）1对卵巢上皮性癌（卵巢癌）细胞顺铂敏感性的影响。

Objective To study changes of cisplatin sensitivity by RNA interfering the excision repair cross-complementing ( ERCC ) 1 gene in ovarian cancer cell lines .

目的氧化/还原因子1（ref1），也称为AP核酸内切酶（APE），是氧化还原和DNA碱基切除修复途径中的重要一员。

Objective Redox factor 1 ( ref-1 ), also known as AP endonuclease ( APE ), is one of the very important components of DNA base excision repair and redox .

GzmA靶向作用于一种与内质网结合的特殊的复合体&SET复合体，其包含3种GzmA底物：核小体装配蛋白SET、DNA结合蛋白HMG-2、具有碱基切除修复作用的核酸内切酶Apel。

A special target of the granzyme A cell death pathway is an endoplasmic reticulum-associated complex , called the SET complex , which contains three granzyme A substrates , the nucleosome assembly protein SET , the DNA-binding protein HMG-2 , and the base excision repair endonuclease Apel .

目的探讨辐射损伤后HR24L修复蛋白复合物的形成，为HR24L参与切除修复和重组修复提供生化证据。

Objective To investigate HR24L repair complex after DNA damage induced by radiation and provide biochemical evidence of the participation of HR24L in DNA excision repair and recombination repair .

人脱细胞羊膜移植物用于兔膀胱切除修复的研究

Reconstruction of rabbit urinary baldder with human acellular amniotic membrane grafts