代谢酶

毒物代谢酶、DNA修复基因多态与儿童白血病遗传易感性

Study on polymorphisms in metabolic enzyme genes , DNA repair genes and individual susceptibility to childhood leukemia

庚肝病毒复制时嘌呤代谢酶活性及IL-6和IL-8的浓度变化

Changes of serum purine metabolic enzyme activities and two cytokinin concentrations in patients with hepatitis G virus replication

药物代谢酶及转运体与前列腺癌药物治疗蛋白激酶C在肾细胞癌多药耐药中的作用

Drug-Metabolizing Enzymes and Transporters : Roles in the Human Prostate Cancer Chemotherapy

[目的]观察蒿甲醚（Art）对日本血吸虫糖代谢酶活性的影响。

Objective To study the effect of artemether on several enzymes involved in carbohydrate metabolism of Schistosoma japonicum .

银杏内酯B对大鼠中性白细胞花生四烯酸代谢酶和细胞内钙水平的影响

Effects of Ginkgolide B on arachidonic acid metabolizing enzymes and level of intracellular calcium in rat polymorphonuclear leukocytes

氯乙烯接触工人DNA损伤与代谢酶基因多态关系研究

Study on the relationship between DNA damage and polymorphisms of metabolizing enzymes of vinyl chloride monomer-exposed workers

结论：ASP具有调节肝脏药物代谢酶活性作用。

Conclusion : ASP can modulate the activities of drug metabolism enzymes .

应用多因素Logistic回归分析，对在食管癌发生中代谢酶基因与修复酶基因的交互作用以及环境-环境、基因-环境的交互作用进行了分析。

The interaction between genes and environmental risk factors was analyzed by multivariate logistic regression model .

槟榔碱代谢酶分布于SD大鼠肝细胞内各亚细胞组分。

Arecoline metabolic enzymes distributed in the subcellular fractions of SD rat liver cells subcellular fractions . 3 .

目的：探讨精神分裂症自由基代谢酶超氧化物歧化酶（SOD）在氟哌啶醇治疗前后的变化。

Objective : To study of effect of haloperidol treatment on superoxide dismutase ( SOD ) in chronic schizophrenic patients .

当受到水稻品种、CO2浓度水平和取食时间的综合影响时，以上代谢酶和保护酶活力会发生显著变化。

There were significant interactions on the activity of metabolism and protective enzymes among CO2 level , rice variety and sampling time .

人群中DNA存在多态性，与药物反应相关的基因多态性可能产生药物效应的个体差异，例如药物代谢酶、药物作用受体以及其它一些与疾病相关基因等。

Polymorphisms exist in human genomic DNA . And some polymorphisms such as metabolic enzymes , drug receptors , and some other genes correlated with diseases may affect the drug responsiveness .

方法DNA损伤采用单细胞凝胶电泳（彗星实验）法，代谢酶活性采用分光光度法，肝功能测定使用自动生化分析仪。

Methods DNA damages were detected by single cell gel electrophoresis ( comet assay ) . The activities of metabolizing enzymes were measured by spectrophotography , and hepatic function was determined by biochemical analyser .

有机酸相关代谢酶的活性表现为：柠檬酸合酶（CS）活性变化与有机酸含量相关性不大；

The activities of organic acids-metaboling enzymes showed : There was no relation between the activity of citrate synthase ( CS ) and organic acids concentration .

漂白纸浆废水对鲫鱼（Carassiusauratus）肝脏微粒体代谢酶的影响

Effects of Bleached - Kraft Pulp Mill Effluent on Microsome Enzyme in Carp ( Carassius auratus ) Liver

Nrf2/ARE对Ⅱ相代谢酶的调节涉及PI3K、MAPK、PKC等细胞内重要信号传导途径。

Regulation of Phase ⅱ enzyme by Nrf2 / ARE is also involved with PI3K , MAPK and PKC signal transduction pathways .

一般认为大肠杆菌RNA聚合酶合成大肠杆菌编码乳糖代谢酶（5300bp的乳糖操纵子）的基因的第一次转录要多长时间？

How long would it take for the E.coli RNA polymerase to synthesize the primary transcript for the E.coli genes encoding the enzymes for lactose metabolism ( the5,300 base pair lac operon )?

MPTP对小鼠黑质及纹状体活性氧自由基代谢酶基因表达的影响

Gene expression of reactive oxygen species scavenging enzymes in substantia nigra and striatum of MPTP treated C57BL mice

冻融使VX非氧化代谢酶活性丧失，但不影响对氧磷水解酶的活性。

These results indicate that the anaerobic VX-metabolizing enzyme is different from soman and paraoxon hydrolases .

大鼠血清中的VX非氧化代谢酶

Anaerobic vx-metabolizing enzyme in rat serum

方法采用社区为基础的病例对照研究，代谢酶基因多态性的检测用PCR和PCRRFLP方法，资料分析用SAS软件进行多因素Logistic回归分析。

Methods Using community based case control design , combined with molecular biological techniques ( PCR and PCR RFLP ), SAS statistics package was applied for multiple variables logistic regression models .

目的研究18α甘草酸二铵（18αGL）对肝脏药物代谢酶的影响。

AIM To study the effect of 18 α glycyrrhizic acid ( 18 α GL ) on hepatic microsomal drug metabolizing enzymes in rats .

目的：研究和探讨吸烟所致宫内发育迟缓（IUGR）大鼠母体肝脏药物代谢酶活性和抗氧化功能的改变及其所带来的毒理学和药理学意义。

AIM : To evaluate the alterations of maternal hepatic drug-metabolizing enzymes and antioxidative function in tobacco-induced intrauterine growth retardation ( IUGR ) .

结论：GSH、GSH-PX、CAT和c-AMP这四项血氧代谢酶在急进高原时，有着较为明显的改变，可反应急性缺氧状态。

Conclusions : The changes of GSH , GSH-PX , CAT and c-AMP level could suggest some acute hypoxic reaction after acute exposed to high altitude .

酸性磷酸酯酶和1-NA是DDVP的重要代谢酶。

Acid-phosphatase and 1-NA were the important metabolic enzymes .

低氧、耐力训练对大鼠代谢酶及肌球蛋白Ca-ATPase的影响

Effects of Hypoxia and Endurance Exercise on Metabolic Enzyme and Myosin Ca-ATPase of Rat

结论VLBW出生时已有骨代谢酶的异常，动态监测ALP的变化可早期发现VLBW骨代谢病。

Conclusions VLBW has abnormal bone metabolism at birth , monitoring serum ALP level change can detect early bone metabolism abnormality .

[方法]大鼠染毒12周，分别在第3、6、9和12周处死动物，DNA损伤采用单细胞凝胶电泳（彗星试验）法，代谢酶活性测定采用分光光度法。

VC was given to rats by in injection 3 times a week for 12 weeks , and rats were killed at the 3rd , 6th , 9th and 12th week . DNA damage was detected by single cell gel electrophoresis ( comet assay ) .

[结论]三唑磷农药亚慢性毒性可能累及代谢酶、免疫、应激和细胞结构成分等方面的变化。浓度为40mg/L的HGS能够抑制HL-60细胞DNA损伤后的修复；

[ Conclusion ] The mechanism of subchronic triazophos poisoning may be involved in metabolism enzymes , immune response-related genes , DNA damage repair genes , stress response genes and membrane proteins .

背景和目的人类N-乙酰基转移酶2（N-acetyltransferase2，NAT2）是催化芳香胺或杂环胺类化合物和磺胺等肼类药物乙酰化灭活的重要代谢酶。

Background and Aims N-acetyltransferase 2 ( NAT2 ) gene is highly polymorphic .