氢氯噻嗪

液相色谱串联质谱法测定人血浆中氯沙坦/氢氯噻嗪的浓度及其人体相对生物利用度研究

Determination the concentration of losartan and hydrochlorothiazide in healthy volunteers and study on its relative bioavailability by LC-MS / MS

氢氯噻嗪与DNA相互作用的光谱研究

Spectroscopic Studies on the Interaction of Hydrochlorothiazide with Calf DNA

复方卡托普利片中卡托普利和氢氯噻嗪的HPLC测定

Determination of Captopril and Hydrochlorothiazide in Compound Captopril Tablets by HPLC

目的：建立反相液相色谱法测定复方利血平片中维生素B6、氢氯噻嗪、硫酸双肼屈嗪、维生素B1、氯氮章和利血平的含量。

Objective : RP - HPLC method was developed to separate and determine six components in compound reserpine tablets .

HPLC测定复方利血平片中氢氯噻嗪的含量

Content determination of Hydrochlorothiazide in Compound Reserpine Tablets by HPLC

HPLC法测定复方罗布麻片Ⅰ中氢氯噻嗪和硫酸双肼屈嗪的含量

Determination of Hydrochlorothiazide and Dihydralazine Sulfate in Compound Kendir Leaves Tablets ⅰ by HPLC

HPLC法测定复方降压胶囊中氢氯噻嗪、地巴唑、氯氮（艹卓）和盐酸异丙嗪的含量

HPLC Determination of Hydrochlorothiazide , Dibazol , Chlordiazepoxide and Promethazine Hydrochloride in Compound Dibazol Capsules

HPLC法测定氯沙坦钾-氢氯噻嗪复方分散片中药物及有关物质的含量

Determination of the contents of drugs and related substances in losartan potassium-hydrochlorothiazide dispersible tablets by HPLC

建立同时测定复方厄贝沙坦片中厄贝沙坦和氢氯噻嗪含量的HPLC方法。

A HPLC method for determination of irbesartan ( 1 ) and hydrochlorothiazide ( 2 ) in compound irbesartan tablets was established .

缬沙坦/氢氯噻嗪治疗原发性高血压有效性和安全性的Meta分析

Meta-analysis of efficacy and safety of valsartan / hydrochlorothiazide in the treatment of essential hypertension

氢氯噻嗪在Caco-2细胞模型中的体外转运研究

Transport characteristics of hydrochlorothiazide in the human intestinal cell line Caco-2

神经干细胞体外三维培养及其模型研究氢氯噻嗪在Caco-2细胞模型中的体外转运研究

Study of 3-D Culture in Vitro and Modeling of NSCs Transport characteristics of hydrochlorothiazide in the human intestinal cell line Caco-2

采用荧光光度法研究了不同酸度下，降压利尿药氢氯噻嗪（Hydrochlorothiazide）与人血清白蛋白（HSA）间的相互作用。

The interaction of human serum albumin ( HSA ) with hydrochlorothiazide by fluorescence quenching method at different pH and temperature was studied .

结论本实验结果表明，用毛细管区带电泳（CZE）法进行氯沙坦钾复方制剂中氢氯噻嗪、氯沙坦钾两种成分的含量测定，方法准确、可靠，简便易行。

CONCLUSION Capillary zone electrophoresis may be an accurate and simple method for the determination of the two components in compound losartan potassium tablets .

目的评价两种氯沙坦/氢氯噻嗪（50mg/12·5mg）复方片剂在中国男性健康志愿者体内的生物等效性。

Aim To evaluate the bioequivalence of two brands of losartan / hydrochlorothiazide ( 50 mg / 12.5 mg ) compound tablets in healthy Chinese male volunteers .

结论联合应用氢氯噻嗪、依那普利、美托洛尔、螺内酯治疗小儿DCM能明显延缓或防止心肌重塑进展，改善心脏功能，提高生存质量。

Conclusion Therapeutic alliance with dihydrochlorothiazide , enalapril , metoprolol and spironolactone may help to postpone or prevent myocardium remodeling , and to recover heart function and raise existing quality in children with DCM .

目的研究氢氯噻嗪（hydrochlorothiazide，Hyd）对大鼠胰岛β细胞功能影响的机制。

Objective To explore the function changes of pancreatic beta cells of rats and its mechanism which were induced by longtime-use of hydrochlorothiazide ( Hyd ) .

相似病例30例（男性23例，女性7例；年龄66±6a）采用氢氯噻嗪25～50mg，po，加螺内酯20～40mg，po，tid，共10～16mo作为对照。

A similar group of 30 patients ( M 23 , F 7 ; age 66 ± 6 a ) received hydrochlorothiazide 25-50 mg po , tid and spironolactone 20-40 mg , po , tid , for 10-16 mo.

选择30名轻中度高血压患者，复方厄贝沙坦（厄贝沙坦150mg/氢氯噻嗪12.5mg）口服，1/d，共8周，观察治疗前后的随测血压和生化指标。

30 patients were treated for 8 weeks with irbesartan ( 150mg ) / hydrochlorothiazide ( 12.5mg ) combination , once daily . Resting blood pressure , biochemical parameters including liver / kidney function , blood electrolyte , and urine analysis were evaluated before and after the treatment .

本法简单、快速、准确、重现性好，适用于复方利血平氢氯噻嗪片中氯化钾含量的测定。

The method is simple , rapid , accurate and reproductive .

3种不同配比的比索洛尔/氢氯噻嗪制剂健康人体药动学研究

Pharmacokinetics of Three Combinations of Bisoprolol with Hydrochlorothiazide in Healthy Volunteers

氢氯噻嗪在小鼠体内的组织分布及药动学研究

Tissue distribution and pharmacokinetics of hydrochlorothiazide in mice by HPLC-MS / MS

双氢氯噻嗪对狗的条件反射的影响

The effect of hydrochlorothiazide on the conditioned reflex in dogs

健康受试者口服复方替米沙坦片后氢氯噻嗪的药物动力学

Pharmacokinetics of Hydrochlorothiazide After Received Tested Compound Telmisartan Tablets in Healthy Volunteers

氢氯噻嗪治疗轻中度高血压病的疗效和安全评价

Clinical Effects and Safety of Hydrochlorothiazide on Essential Hypertension

氢氯噻嗪的抗利尿作用及其对大鼠组织含水量的影响

Antidiuretic effect of hydrochlorothiazide and its influence on tissue water content in rats

氢氯噻嗪与其他药合用的降压作用

Hypotensive effect of combination of chlorothiazide with other drugs

人血浆中氢氯噻嗪的LC-MS/MS测定及药动学

Determination of Hydrochlorothiazide in Human Plasma by LC-MS / MS and Its Pharmacokinetics

熔融高速搅拌法制备氢氯噻嗪缓释微丸

Sustained-release pellets of hydrochlorothiazide prepared by the melt pelletization in a high-speed mixer

α-内收蛋白基因多态性与氢氯噻嗪降压疗效的相关性研究

Association of polymorphism in α - adducin gene with antihypertensive effect of Hydrochlorothiazide