鸟苷酸环化酶

低O2高CO2对大鼠肺中小动脉可溶性鸟苷酸环化酶基因及其蛋白表达的影响

Effects of hypoxia and hypercapnia on expression of soluble guanylate cyclase in rat pulmonary artery

吗啡依赖小鼠脑组织cGMP水平、鸟苷酸环化酶及磷酸二酯酶活性的调节

Modulation of cGMP levels , soluble guanylate cyclase and phosphodiesterase activities in brain of morphine dependent mice

鸟苷酸环化酶C及尾型同源盒转录因子-2在胃腺癌中的研究进展

Research progress of GC-C and CDX-2 in the gastric adenocarcinoma

鸟苷酸环化酶C研究进展

Progression of guanylyl cyclase - C

大肠癌患者外周血中鸟苷酸环化酶C的表达及其意义

Expression of guanylyl cyclase C mRNA in peripheral blood from patients with colorectal cancers and its significance

利用这一特点，使用与ST连接的纳米颗粒结合近红外线或无线电频率能量吸收热烧蚀术，使得鸟苷酸环化酶C成为了转移瘤消融的一个潜在靶。

This makes GCC a potential target for metastatic tumor ablation using ST-bound nanoparticles in combination with thermal ablation with near-infrared or radiofrequency energy absorption .

鸟苷酸环化酶抑制剂ODQ对星形胶质细胞cGMP及GFAP的影响

The effects of guanylate cyclase inhibitor ODQ on astrocytes cGMP and GFAP

NO这些作用通过的通路不涉及到鸟苷酸环化酶和cGMP依赖的蛋白激酶。

NO exerted these effects through a pathway that does not involve guanylate cyclase and cGMP dependent protein kinase .

目的观察创伤性休克兔血浆一氧化氮（NitricOXide，NO）的动态变化及鸟苷酸环化酶抑制药亚甲蓝（methyleneblue，MB）的干预作用。

Objective To observe the changes of plasma nitric oxide in rabbits with traumatic shock and the intervention of methylene blue ( MB ), a guanylate cyclase inhibitor .

目的观察鸟苷酸环化酶抑制药亚甲蓝（MB）对感染性休克犬血液动力学和氧合功能的影响。

Objective To study the effects of methylene blue ( MB ), a guanylate cyclase inhibitor , on hemodynamics and oxygenation in dog with septic shock .

目的：探讨慢性低O2高CO2时大鼠肺动脉可溶性鸟苷酸环化酶（sGC）基因及其蛋白表达的变化。

AIM : To investigate the expression of soluble guanylate cyclase protein and its mRNA in rat pulmonary artery after exposure to hypoxia and hypercapnia .

AA增高可激活鸟苷酸环化酶、抑制腺苷酸环化酶，使cGMP增多，cAMP减少而引起表皮细胞增殖。

Elevation of AA may activate the guanyl cyclase and inhibit the adenyl cyclase , causing increase in cGMP and decrease in cAMP , and hence cause proliferation of epidermal cells .

目的：探讨鸟苷酸环化酶（sGC）抑制剂甲基蓝（MB）对阿片耐受和依赖的阻断作用。

AIM : To explore the mechanism of blockade of opiate tolerance and dependence by methylene blue ( MB ), a soluble guanylyl cyclase ( sGC ) inhibitor .

目的观察大鼠慢性缺氧高二氧化碳（CO2）肺动脉高压模型肺动脉可溶性鸟苷酸环化酶（sGC）的表达及其活性。

Objective To investigate the mRNA and protein expressions of soluble guanylate cyclase ( sGC ) and its enzyme activity in pulmonary hypertension rat model which was reproduced by hypoxia and hypercapnia .

目的探导可溶性鸟苷酸环化酶（sGC）α1、β1亚基蛋白在大鼠脑缺血再灌注后血管平滑肌中的表达及其意义。

Objective To explore the expressions of α 1 and β 1 subunits of the soluble guanylate cyclase ( sGC α 1 , β 1 ) in the vascular smooth muscle after cerebral ischemia-reinfusion in rats and their significance .

心房肽A型受体基因表达及受体鸟苷酸环化酶活性的调节研究

Regulation of Natriuretic Peptide Receptor-A Gene Expression and Guanylyl Cyclase-A Activity

大鼠慢性缺氧高二氧化碳肺动脉高压模型可溶性鸟苷酸环化酶的表达

Study on soluble guanylate cyclase in pulmonary hypertension rat model

可溶性鸟苷酸环化酶的卟啉结合域结构模拟及计算分析

The Modelling and Computation Analysis of the Soluble Guanylate Cyclase Heme Binding Domain

哺乳动物可溶性鸟苷酸环化酶的表达及其调控

Expression and Regulation of Soluble Guanylate Cyclases in Mammalian

肺动脉高压大鼠一氧化氮及过氧化氢依赖的可溶性鸟苷酸环化酶通路的变化

Changes of NO - and H_2O_2-dependent soluble guanylate cyclase pathway in the hypoxic hypercapnic pulmonary hypertension rats

可溶性鸟苷酸环化酶α1、β1在脑缺血再灌注后血管平滑肌中表达的实验研究

Expressions of Soluble Guanylate Cyclase α _1 and β _1 in Vascular Smooth Muscle after Cerebral Ischemia-reinfusion in Rats

可溶性鸟苷酸环化酶α1和β1亚基在雄性大鼠生殖系统中表达的研究

Expression Pattern of Soluble Guanylate Cyclase α 1 and β 1 Subunits in the Male Reproductive System of Rat

其机制可能是，细胞巯基耗竭，使鸟苷酸环化酶活性降低，致血管平滑肌松弛作用减弱。

The mechanism is probably that the consumption of cell mercapto lowers the activity of guanylate cyclase , thus weakening the slackness of blood vessel 's smooth muscles .

心房利钠肽属于利钠肽家族，其通过与受体结合激活鸟苷酸环化酶，促进细胞内环鸟苷酸水平升高而发挥生物学功能。

Atrial natriuretic peptide ( ANP ) is a member of the natriuretic peptide family . By binding with its receptor and thereafter activating guanylate cyclase , ANP increases intracellular cGMP level and hence produces biological effects .

结论：①在基础状态下纹状体的环鸟苷酸约50%来源于可溶性鸟苷酸环化酶的激活。

CONCLUSION : ① The results suggest that under basal condition , about 50 % of the cGMP in the striatum seem to originate from the soluble guanylyl cyclase .