顺反异构酶

102的基因转录调节和翻译调控相关蛋白表达也出现下降：如肽基脯氨酰顺反异构酶，PPR基因家族（102，D21）；多聚ADP-核糖水解酶（102，D22）。

102 regulation of gene transcription and translation control related protein expression also decreased : such as peptidyl-prolyl cis-trans isomerase , PPR gene family ; poly-ADP-ribose hydrolase .

CyPs具有肽脯氨酰顺反异构酶活性，催化蛋白质折叠过程，尤其是富含脯氨酸的蛋白质折叠，并且起着分子伴侣的作用，同时参与相关的生物学过程如细胞繁殖和细胞间信号传导。

CyPs possess peptidyl-prolyl cis-trans isomerase activity , which can catalyse the process of protein folding and work as chaperones . CyPs are also involved in other correlated biological process such as cellar multiplication and intercellular communication .

43个蛋白质中有4个表达量变化显著的被成功鉴定，分别为钴胺素生物合成蛋白、肽基脯氨酰顺反异构酶、核苷二磷酸激酶和N-乙酰-γ-谷氨酰磷酸脱氢酶。

Four proteins of cobalamin biosynthesis protein , N-acetyl-gamma-glutamyl-phosphate reductase , peptidyl prolyl cis-trans isomerase and nucleoside diphosphate kinase were successfully identified .

亲环素A（CyPA）是免疫抑制药物环孢素A的受体，是胞质内一种具有肽基-脯氨酸顺/反异构酶活性的蛋白质。

Cyclophilin A ( CyPA ) is a cytoplasmic protein which binds to immunosuppressive drug & cyclosporin A and possesses peptidyl prolyl cis trans isomerase activity .

同时表达下调的蛋白质有磷酸丙糖异构酶、神经鞘氨醇磷酸化受体、热休克蛋白10、肽酰-脯氨酰-顺反式异构酶A。

Meanwhile , triose-phosphate isomerase ( TPIS ), sphingosine 1-phosphate receptor 1 ( S1P1 ), heat-shock protein 10 ( HSP10 ), peptidyl-prolyl cis-trans isomerase A ( PPIase A ) were down-regulated .